Wnt beta Catenin TCF

The role of Wnt signalling in cardiac development and tissue remodelling in the mature heart.
[16860783] Cardiovasc Res 72(2): 198-209 (2006)

The wnt-frizzled cascade in cardiovascular disease.
[12062705] Cardiovasc Res 55(1): 16-24 (2002)

Wnt/beta-catenin signaling: a novel target for therapeutic intervention of fibrotic kidney disease.
[20162391] Arch Pharm Res 32(12): 1653-62 (2009)

Regulating the regulators: routing the Wnt-beta-catenin--Lef signals.
[15245452] J Invest Dermatol 123(2): VIII-X (2004)

Wnt signaling from development to disease: insights from model systems.
[20066091] Cold Spring Harb Perspect Biol 1(2): a002881 (2009)

Wnt signaling and stem cell control.
[18392048] Cell Res 18(5): 523-7 (2008)

Wnt signaling control of bone cell apoptosis.
[18212734] Cell Res 18(2): 248-53 (2008)

Regulation of hematopoiesis and the hematopoietic stem cell niche by Wnt signaling pathways.
[17768401] Cell Res 17(9): 746-58 (2007)

Wnt signaling in disease and in development.
[15686623] Cell Res 15(1): 28-32 (2005)

Wnt/Frizzled signaling in angiogenesis.
[18253847] Angiogenesis 11(1): 63-9 (2008)

Wnt signaling in the vasculature.
[12549854] Angiogenesis 5(1-2): 1-9 (2002)

Wnt trafficking: new insights into Wnt maturation, secretion and spreading.
[20477987] Traffic 11(10): 1265-71 (2010)

From individual Wnt pathways towards a Wnt signalling network.
[18192173] Philos Trans R Soc Lond B Biol Sci 363(1495): 1333-47 (2008)

Wnt signaling inside the nucleus.
[18177486] Cancer Sci 99(4): 631-7 (2008)

Tumor formation due to abnormalities in the beta-catenin-independent pathway of Wnt signaling.
[18271916] Cancer Sci 99(2): 202-8 (2008)

Wnt signaling and neurite outgrowth: insights and questions.
[17627619] Cancer Sci 98(9): 1311-7 (2007)

Tumor formation by genetic mutations in the components of the Wnt signaling pathway.
[12824913] Cancer Sci 94(3): 225-9 (2003)

Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways.
[10630639] Oncogene 18(55): 7860-72 (1999)

Is there more to Wnt signalling in breast cancer than stabilisation of beta-catenin?
[19664193] Breast Cancer Res 11(4): 105 (2009)

Links between transforming growth factor-beta and canonical Wnt signaling yield new insights into breast cancer susceptibility, suppression and tumor heterogeneity.
[19519951] Breast Cancer Res 11(3): 103 (2009)

Wnt signalling via the epidermal growth factor receptor: a role in breast cancer?
[14979908] Breast Cancer Res 6(2): 65-8 (2004)

Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know?
[16126938] Endocr Rev 26(7): 898-915 (2005)

Mechanistic insights from structural studies of beta-catenin and its binding partners.
[17881495] J Cell Sci 120(Pt 19): 3337-44 (2007)

Wnt signalling: variety at the core.
[17251379] J Cell Sci 120(Pt 3): 385-93 (2007)

Wnt signaling: complexity at the surface.
[16443747] J Cell Sci 119(Pt 3): 395-402 (2006)

Secreted antagonists of the Wnt signalling pathway.
[12775774] J Cell Sci 116(Pt 13): 2627-34 (2003)

Plakoglobin and beta-catenin: protein interactions, regulation and biological roles.
[10954412] J Cell Sci 113 ( Pt 18)(-): 3127-39 (2000)

Antiangiogenesis to treat cancer and intraocular neovascular disorders.
[17259997] Lab Invest 87(3): 227-30 (2007)

To beta or not to beta: canonical beta-catenin signaling pathway and ovarian development.
[18985752] Dev Dyn 237(12): 3672-80 (2008)

The Wnt connection to tumorigenesis.
[15349822] Int J Dev Biol 48(5-6): 477-87 (2004)

A tight control over Wnt action.
[10668977] Int J Dev Biol 43(7): 675-80 (1999)

Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal.
[18263841] Development 135(5): 789-98 (2008)

The making of Wnt: new insights into Wnt maturation, sorting and secretion.
[17138665] Development 134(1): 3-12 (2007)

Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface.
[14530294] Development 130(22): 5297-305 (2003)

Catenins: keeping cells from getting their signals crossed.
[17084354] Dev Cell 11(5): 601-12 (2006)

Wnt signaling and the activation of myogenesis in mammals.
[10601008] EMBO J 18(24): 6867-72 (1999)

Regulation of Wnt protein secretion and its role in gradient formation.
[18787559] EMBO Rep 9(10): 977-82 (2008)

Wnt pathway: a new role in regulation of inflammation.
[18296599] Arterioscler Thromb Vasc Biol 28(3): 400-2 (2008)

Canonical WNT signalling controls hair follicle spacing.
[19262137] Cell Adh Migr 1(3): 149-51 (2007)

Re-evaluating the role of Frat in Wnt-signal transduction.
[16082208] Cell Cycle 4(8): 1065-72 (2005)

Beta-catenin nuclear activation: common pathway between Wnt and growth factor signaling in vascular smooth muscle cell proliferation?
[17158343] Circ Res 99(12): 1287-9 (2006)

Wnt/Notch signalling and information processing during development.
[18192283] Development 135(3): 411-24 (2008)

LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way.
[15084453] Development 131(8): 1663-77 (2004)

Curbing the nuclear activities of beta-catenin. Control over Wnt target gene expression.
[11256619] EMBO Rep 1(1): 24-8 (2000)

Pathophysiological aspects of Wnt-signaling in endocrine disease.
[19246555] Eur J Endocrinol 160(5): 731-7 (2009)

Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice.
[18765787] Genes Dev 22(17): 2308-41 (2008)

Wnt signaling: is the party in the nucleus?
[16751178] Genes Dev 20(11): 1394-404 (2006)

CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling.
[16481469] Genes Dev 20(4): 399-410 (2006)

Wnt signaling in the intestinal epithelium: from endoderm to cancer.
[15833914] Genes Dev 19(8): 877-90 (2005)

Wnt signaling and cancer.
[10921899] Genes Dev 14(15): 1837-51 (2000)

Wnt signaling: a common theme in animal development.
[9407023] Genes Dev 11(24): 3286-305 (1997)

Signal transduction through beta-catenin and specification of cell fate during embryogenesis.
[8895655] Genes Dev 10(20): 2527-39 (1996)

Canonical Wnt signaling: high-throughput RNAi widens the path.
[16168092] Genome Biol 6(9): 231 (2005)

Wnt signaling in polycystic kidney disease.
[17429050] J Am Soc Nephrol 18(5): 1389-98 (2007)

Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors.
[16793760] J Biol Chem 281(32): 22429-33 (2006)

Sclerostin and Wnt signaling--the pathway to bone strength.
[16330810] J Clin Endocrinol Metab 90(12): 6741-3 (2005)

Wnt signaling in neural circuit development.
[16280576] J Neurosci 25(45): 10376-8 (2005)

The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus.
[18599616] Mol Endocrinol 22(11): 2383-92 (2008)

Gone with the Wnts: beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism.
[17622581] Mol Endocrinol 21(11): 2605-14 (2007)

Wnt/beta-catenin signaling in development and disease.
[17081971] Cell 127(3): 469-80 (2006)

A dedicated Wnt secretion factor.
[16678089] Cell 125(3): 432-3 (2006)

Wnt pathway activation: new relations and locations.
[15652476] Cell 120(1): 11-4 (2005)

Linking colorectal cancer to Wnt signaling.
[11057903] Cell 103(2): 311-20 (2000)

Wnts as retrograde signals for axon and growth cone differentiation.
[10721986] Cell 100(5): 495-7 (2000)

Structurally related receptors and antagonists compete for secreted Wnt ligands.
[9118212] Cell 88(6): 725-8 (1997)

beta-Catenin: a pivot between cell adhesion and Wnt signalling.
[15668160] Curr Biol 15(2): R64-7 (2005)

Heads or tails: Wnts and anterior-posterior patterning.
[11553348] Curr Biol 11(17): R713-24 (2001)

Wnt signaling: an embarrassment of receptors.
[11137030] Curr Biol 10(24): R919-22 (2000)

Wnt signaling: Moving in a new direction.
[10959830] Curr Biol 10(15): R562-4 (2000)

Wnt signalling shows its versatility.
[10508601] Curr Biol 9(18): R684-7 (1999)

Wingless signaling: the inconvenient complexities of life.
[9501979] Curr Biol 8(4): R140-4 (1998)

A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling.
[12967557] Dev Cell 5(3): 367-77 (2003)

WNT/beta-catenin signaling in liver health and disease.
[17464972] Hepatology 45(5): 1298-305 (2007)

Regulation of Wnt signaling by protein-protein interaction and post-translational modifications.
[16520547] Exp Mol Med 38(1): 1-10 (2006)

The adenomatous polyposis coli tumor suppressor and Wnt signaling in the regulation of apoptosis.
[19928354] Adv Exp Med Biol 656(-): 75-84 (2009)

Wnt signaling and pulmonary fibrosis.
[12707021] Am J Pathol 162(5): 1393-7 (2003)

Wnt signaling, lgr5, and stem cells in the intestine and skin.
[19197002] Am J Pathol 174(3): 715-21 (2009)

Development of small molecules targeting the Wnt pathway for the treatment of colon cancer: a high-throughput screening approach.
[20508156] Am J Physiol Gastrointest Liver Physiol 299(2): G293-300 (2010)

The various roles of ubiquitin in Wnt pathway regulation.
[20930545] Cell Cycle 9(18): 3700-9 (2010)

Multiple roles of canonical Wnt signaling in cell cycle progression and cell lineage specification in neural development.
[15118414] Cell Cycle 3(6): 701-3 (2004)

Turning the tables: Myc activates Wnt in breast cancer.
[17726380] Cell Cycle 6(21): 2625-7 (2007)

Wnt signaling molecules in left ventricular remodeling: focus on dishevelled 1.
[20176999] Hypertension 55(4): 852-4 (2010)

Cardiac hypertrophy and the Wnt/Frizzled pathway.
[17210831] Hypertension 49(3): 427-8 (2007)

WNT signaling in adult cardiac hypertrophy and remodeling: lessons learned from cardiac development.
[21071717] Circ Res 107(10): 1198-208 (2010)

Wnt signaling and aging-related heart disorders.
[21106946] Circ Res 107(11): 1295-303 (2010)

The role of Dickkopf-1 in bone development, homeostasis, and disease.
[18687985] Blood 113(3): 517-25 (2009)

The Wnt/beta-catenin signaling pathway as a target in drug discovery.
[17721040] J Pharmacol Sci 104(4): 293-302 (2007)

Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: inhibitors of the Wnt/beta-catenin signaling pathway as novel anticancer drugs.
[19179804] J Pharmacol Sci 109(2): 179-83 (2009)

Lithium and neuropsychiatric therapeutics: neuroplasticity via glycogen synthase kinase-3beta, beta-catenin, and neurotrophin cascades.
[19423950] J Pharmacol Sci 110(1): 14-28 (2009)

Mesodermal fate decisions of a stem cell: the Wnt switch.
[18528633] Cell Mol Life Sci 65(17): 2658-74 (2008)

Wnt/beta-catenin signaling in adipogenesis and metabolism.
[17997088] Curr Opin Cell Biol 19(6): 612-7 (2007)

Wnt/beta-catenin signaling: new (and old) players and new insights.
[18339531] Curr Opin Cell Biol 20(2): 119-25 (2008)

Regulation of bone mass by Wnt signaling.
[16670761] J Clin Invest 116(5): 1202-9 (2006)

Wnt signalling during limb development.
[12455630] Int J Dev Biol 46(7): 927-36 (2002)

Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway.
[19761865] Semin Cell Dev Biol 20(8): 986-97 (2009)

Wnt signalling in development and disease. Max Delbrück Center for Molecular Medicine meeting on Wnt signaling in Development and Disease.
[18188179] EMBO Rep 9(2): 134-8 (2008)

Cross-talk between transforming growth factor-beta and Wingless/Int pathways in lung development and disease.
[20219694] Int J Biochem Cell Biol 42(6): 809-12 (2010)

Role of Wnt/β-catenin signaling in liver metabolism and cancer.
[19747566] Int J Biochem Cell Biol 43(7): 1021-9 (2011)

Organ patterning in the adult stage: the role of Wnt/beta-catenin signaling in liver zonation and beyond.
[19705440] Dev Dyn 239(1): 45-55 (2010)

Wnt modulators in the biotech pipeline.
[20014100] Dev Dyn 239(1): 102-14 (2010)

Ror-family receptor tyrosine kinases in noncanonical Wnt signaling: their implications in developmental morphogenesis and human diseases.
[19530173] Dev Dyn 239(1): 1-15 (2010)

Crosstalk between Wnt and bone morphogenic protein signaling: a turbulent relationship.
[19544585] Dev Dyn 239(1): 16-33 (2010)

Regulation of Wnt/beta-catenin signaling by protein kinases.
[19623618] Dev Dyn 239(1): 34-44 (2010)

Interactions between SOX factors and Wnt/beta-catenin signaling in development and disease.
[19655378] Dev Dyn 239(1): 56-68 (2010)

Wnt signaling modulates pre- and postsynaptic maturation: therapeutic considerations.
[19681159] Dev Dyn 239(1): 94-101 (2010)

Wnt won the war: antagonistic role of Wnt over Shh controls dorso-ventral patterning of the vertebrate neural tube.
[19681160] Dev Dyn 239(1): 69-76 (2010)

Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis.
[19681164] Dev Dyn 239(1): 77-93 (2010)

Targeting Wnt signaling: can we safely eradicate cancer stem cells?
[20530697] Clin Cancer Res 16(12): 3153-62 (2010)

Wnt/beta-catenin signaling in T-cell immunity and cancer immunotherapy.
[20688898] Clin Cancer Res 16(19): 4695-701 (2010)

WNT signaling pathway and stem cell signaling network.
[17634527] Clin Cancer Res 13(14): 4042-5 (2007)

Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment.
[21668411] Biochem J 437(1): 1-12 (2011)

Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia.
[21289065] Genes Dev 25(3): 201-13 (2011)

Wnt signaling pathways meet Rho GTPases.
[19204114] Genes Dev 23(3): 265-77 (2009)

Drug discovery approaches to target Wnt signaling in cancer stem cells.
[21317452] Oncotarget 1(7): 563-77 (2010)

GSK3: a multifaceted kinase in Wnt signaling.
[19884009] Trends Biochem Sci 35(3): 161-8 (2010)

WNT signaling in lung disease: a failure or a regeneration signal?
[19329555] Am J Respir Cell Mol Biol 42(1): 21-31 (2010)

Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton.
[17395698] Endocrinology 148(6): 2635-43 (2007)

In vivo analysis of Wnt signaling in bone.
[17395705] Endocrinology 148(6): 2630-4 (2007)

mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer.
[15851011] Mol Ther 11(5): 724-33 (2005)

On growth and form: a Cartesian coordinate system of Wnt and BMP signaling specifies bilaterian body axes.
[20179091] Development 137(6): 845-57 (2010)

Towards an integrated view of Wnt signaling in development.
[19736321] Development 136(19): 3205-14 (2009)

The what, where, when and how of Wnt/β-catenin signaling in pancreas development.
[18953422] Organogenesis 4(2): 81-6 (2008)

Wnt signaling in skin organogenesis.
[19279724] Organogenesis 4(2): 123-33 (2008)

Wnt signaling in breast organogenesis.
[19279723] Organogenesis 4(2): 116-22 (2008)

Wnt signaling in limb organogenesis.
[19279722] Organogenesis 4(2): 109-15 (2008)

Wnt signaling in lung organogenesis.
[19279721] Organogenesis 4(2): 100-8 (2008)

Wnt/beta-catenin signaling in hepatic organogenesis.
[19279720] Organogenesis 4(2): 92-9 (2008)

Striking the target in Wnt-y conditions: intervening in Wnt signaling during cancer progression.
[20211149] Biochem Pharmacol 80(5): 702-11 (2010)

AHR-dependent misregulation of Wnt signaling disrupts tissue regeneration.
[18938144] Biochem Pharmacol 77(4): 498-507 (2009)

Wnt signaling in prostate development and carcinogenesis.
[21475372] Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 155(1): 11-8 (2011)

Wnt signaling and skeletal development.
[18164181] Cell Signal 20(6): 999-1009 (2008)

The canonical Wnt signalling pathway and its APC partner in colon cancer development.
[16840506] Gut 56(3): 417-25 (2007)

A Wnt survival guide: from flies to human disease.
[19177135] J Invest Dermatol 129(7): 1614-27 (2009)

Role of Wnt canonical pathway in hematological malignancies.
[20843302] J Hematol Oncol 3(-): 33 (2010)

Rogue proliferation versus restorative protection: where do we draw the line for Wnt and forkhead signaling?
[18554157] Expert Opin Ther Targets 12(7): 905-16 (2008)

Wnt signaling as a therapeutic target for bone diseases.
[19335070] Expert Opin Ther Targets 13(4): 485-96 (2009)

WNT/beta-catenin signaling in nephron progenitors and their epithelial progeny.
[18633347] Kidney Int 74(8): 1004-8 (2008)

Winding through the WNT pathway during cellular development and demise.
[16267791] Histol Histopathol 21(1): 103-24 (2006)

A re-evaluation of the "oncogenic" nature of Wnt/beta-catenin signaling in melanoma and other cancers.
[20603725] Curr Oncol Rep 12(5): 314-8 (2010)

Hear the Wnt Ror: how melanoma cells adjust to changes in Wnt.
[19708915] Pigment Cell Melanoma Res 22(6): 724-39 (2009)

Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis.
[12481159] Digestion 66(3): 131-44 (2002)

Wnt signalling in implantation, decidualisation and placental differentiation--review.
[20716463] Placenta 31(10): 839-47 (2010)

The Wnt-dependent signaling pathways as target in oncology drug discovery.
[16683072] Invest New Drugs 24(4): 263-80 (2006)

Wnt signaling and colon carcinogenesis: beyond APC.
[21483657] J Carcinog 10(-): 5 (2011)

The emerging role of Wnt/PCP signaling in organ formation.
[19250029] Zebrafish 6(1): 9-14 (2009)

Wnt signaling in development and disease.
[19765659] Neurobiol Dis 38(2): 148-53 (2010)

Convergence between Wnt-β-catenin and EGFR signaling in cancer.
[20828404] Mol Cancer 9(-): 236 (2010)

MicroRNA roles in beta-catenin pathway.
[20858269] Mol Cancer 9(-): 252 (2010)

Epithelial stem cells: an epigenetic and Wnt-centric perspective.
[20564229] J Cell Biochem 110(6): 1279-87 (2010)

Wnt signaling and human diseases: what are the therapeutic implications?
[17211410] Lab Invest 87(2): 97-103 (2007)

Targeting mediators of Wnt signalling pathways by GnRH in gonadotropes.
[20133385] J Mol Endocrinol 44(4): 195-201 (2010)

Cystic kidney disease: the role of Wnt signaling.
[20576469] Trends Mol Med 16(8): 349-60 (2010)

Epigenetic gene silencing in the Wnt pathway in breast cancer.
[18398311] Epigenetics 3(2): 59-63 (2008)

Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers.
[19633433] Epigenetics 4(5): 307-12 (2009)

TCF1 and beta-catenin regulate T cell development and function.
[20082155] Immunol Res 47(1-3): 45-55 (2010)

Evolution of the Wnt pathways.
[19109698] Methods Mol Biol 469(-): 3-18 (2008)

The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis.
[18581335] Eur J Immunol 38(7): 1788-94 (2008)

Wnt signal transduction pathway and apoptosis: a review.
[20591184] Cancer Cell Int 10(-): 22 (2010)

Wnt/beta-catenin signaling: components, mechanisms, and diseases.
[19619488] Dev Cell 17(1): 9-26 (2009)

Wnt up your mind - intervention strategies for S100A4-induced metastasis in colon cancer.
[20093727] Gen Physiol Biophys 28 Spec No Focus(-): F55-64 (2009)

Effects of thiazolidinediones on differentiation, proliferation, and apoptosis.
[17579114] Mol Cancer Res 5(6): 523-30 (2007)

The links between transcription, beta-catenin/JNK signaling, and carcinogenesis.
[19671687] Mol Cancer Res 7(8): 1189-96 (2009)

Wnt/Planar cell polarity signaling: a new paradigm for cancer therapy.
[19671746] Mol Cancer Ther 8(8): 2103-9 (2009)

Targeting Wnt signaling in colon cancer stem cells.
[21159886] Clin Cancer Res 17(4): 647-53 (2011)

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