Signal transduction

Signaling takes a breath--new quantitative perspectives on bioenergetics and signal transduction.
[11672532] Immunity 15(4): 497-502 (2001)

A functional proteomics approach to signal transduction.
[12795412] Recent Prog Horm Res 58(-): 1-24 (2003)

Signalling: basics and evolution.
[15218530] Acta Biochim Pol 51(2): 281-98 (2004)

Lipids and signal transduction in the nucleus.
[11732623] Acta Biochim Pol 48(2): 541-9 (2001)

Intracellular transduction using cell-penetrating peptides.
[20237640] Mol Biosyst 6(4): 628-40 (2010)

Receptor tyrosine kinase signaling: a view from quantitative proteomics.
[19756300] Mol Biosyst 5(10): 1112-21 (2009)

Sensory cilia and integration of signal transduction in human health and disease.
[17241444] Traffic 8(2): 97-109 (2007)

Current Screens Based on the AlphaScreen Technology for Deciphering Cell Signalling Pathways.
[19794881] Curr Genomics 10(2): 93-101 (2009)

Signal transduction pathways that regulate cell survival and cell death.
[9916983] Oncogene 17(25): 3207-13 (1998)

Anti-apoptotic versus pro-apoptotic signal transduction: checkpoints and stop signs along the road to death.
[9779994] Oncogene 17(11 Reviews): 1475-82 (1998)

Transcriptional regulation by extracellular signals: mechanisms and specificity.
[7834740] Cell 80(2): 199-211 (1995)

Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus.
[7583121] Curr Biol 5(7): 747-57 (1995)

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging.
[21422497] Aging (Albany NY) 3(3): 192-222 (2011)

Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells.
[19895837] Adv Enzyme Regul 50(1): 285-307 (2010)

Dysregulation of janus kinases and signal transducers and activators of transcription in cancer.
[22016828] Am J Cancer Res 1(6): 806-16 (2011)

Na(+)/H(+) exchanger NHE1 as plasma membrane scaffold in the assembly of signaling complexes.
[15355855] Am J Physiol Cell Physiol 287(4): C844-50 (2004)

The mitochondrial component of intracrine action.
[20622110] Am J Physiol Heart Circ Physiol 299(3): H577-83 (2010)

Molecular and mechanical synergy: cross-talk between integrins and growth factor receptors.
[15276463] Cardiovasc Res 63(3): 381-90 (2004)

Regulation of epidermal growth factor receptor signalling by inducible feedback inhibitors.
[21576352] J Cell Sci 124(Pt 11): 1785-93 (2011)

Trafficking of signaling modules by kinesin motors.
[12730289] J Cell Sci 116(Pt 11): 2125-35 (2003)

Signalling complexes and clusters: functional advantages and methodological hurdles.
[20130139] J Cell Sci 123(Pt 3): 309-20 (2010)

Signaling threshold regulation by the Ras effector IMP.
[19091743] J Biol Chem 284(17): 11007-11 (2009)

The Hsp90 chaperone machinery regulates signaling by modulating ligand binding clefts.
[18515355] J Biol Chem 283(34): 22885-9 (2008)

Nuclear mode of the EGFR signaling network: biology, prognostic value, and therapeutic implications.
[20670598] Discov Med 10(50): 44-51 (2010)

Pharmacology of intracellular signalling pathways.
[16402119] Br J Pharmacol 147 Suppl 1(-): S38-45 (2006)

Lipid signaling in T-cell development and function.
[20943760] Cold Spring Harb Perspect Biol 2(11): a002428 (2010)

Transport of exogenous growth factors and cytokines to the cytosol and to the nucleus.
[12506129] Physiol Rev 83(1): 163-82 (2003)

Signal transduction pathways that function in both development and innate immunity.
[20131356] Dev Dyn 239(5): 1330-6 (2010)

Endosomes: a legitimate platform for the signaling train.
[19822761] Proc Natl Acad Sci U S A 106(42): 17615-22 (2009)

Spatially distributed cell signalling.
[19800332] FEBS Lett 583(24): 4006-12 (2009)

4E-binding protein 1: a key molecular "funnel factor" in human cancer with clinical implications.
[17699757] Cancer Res 67(16): 7551-5 (2007)

Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways.
[15179030] Mol Cells 17(2): 188-202 (2004)

Endocytosis and signalling: intertwining molecular networks.
[19696798] Nat Rev Mol Cell Biol 10(9): 609-22 (2009)

Four-dimensional organization of protein kinase signaling cascades: the roles of diffusion, endocytosis and molecular motors.
[12756289] J Exp Biol 206(Pt 12): 2073-82 (2003)

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health.
[21411864] Oncotarget 2(3): 135-64 (2011)

Paracrystals of STAT proteins and their dissolution by SUMO: how reduced transcription factor solubility increases cytokine signaling.
[21795761] Oncotarget 2(7): 527-8 (2011)

Scaffold proteins: hubs for controlling the flow of cellular information.
[21551057] Science 332(6030): 680-6 (2011)

Cell signaling in space and time: where proteins come together and when they're apart.
[19965465] Science 326(5957): 1220-4 (2009)

Using plasma membrane nanoclusters to build better signaling circuits.
[18620858] Trends Cell Biol 18(8): 364-71 (2008)

A vital link between energy and signal transduction.
[16156778] FEBS J 272(18): 4561-4 (2005)

Examining multiprotein signaling complexes from all angles.
[16262684] FEBS J 272(21): 5426-35 (2005)

Methods of analysis for chemicals that promote/disrupt cellular signaling.
[12036116] Anal Sci 18(5): 503-16 (2002)

Cellular signaling perturbation by natural products.
[19298854] Cell Signal 21(11): 1541-7 (2009)

Intracellular signal pathways: potential for therapies.
[19772834] Curr Rheumatol Rep 11(5): 378-85 (2009)

Computational molecular biology approaches to ligand-target interactions.
[20119480] HFSP J 3(4): 228-39 (2009)

Protein and lipid kinase inhibitors as targeted anticancer agents of the Ras/Raf/MEK and PI3K/PKB pathways.
[18523868] Purinergic Signal 5(1): 117-25 (2009)

Imaging of persistent cAMP signaling by internalized G protein-coupled receptors.
[20378719] J Mol Endocrinol 45(1): 1-8 (2010)

Shuffling the cards in signal transduction: Calcium, arachidonic acid and mechanosensitivity.
[21537474] World J Biol Chem 2(4): 59-66 (2011)

Structural analysis of hubs in human NR-RTK network.
[21974810] Biol Direct 6(-): 49 (2011)

Protein kinases and phosphatases in the control of cell fate.
[21904669] Enzyme Res 2011(-): 329098 (2011)

Vinexin, CAP/ponsin, ArgBP2: a novel adaptor protein family regulating cytoskeletal organization and signal transduction.
[11937713] Cell Struct Funct 27(1): 1-7 (2002)

Interplay between cell adhesion and growth factor receptors: from the plasma membrane to the endosomes.
[19722108] Cell Tissue Res 339(1): 111-20 (2010)

Reciprocal regulation of metabolic and signaling pathways.
[20334672] BMC Genomics 11(-): 197 (2010)

Cross-regulation of signaling pathways: an example of nuclear hormone receptors and the canonical Wnt pathway.
[20138864] Exp Cell Res 316(11): 1763-72 (2010)

Trafficking of receptor tyrosine kinases to the nucleus.
[18951890] Exp Cell Res 315(9): 1556-66 (2009)

Enhanced interrogation: emerging strategies for cell signaling inhibition.
[20520657] Nat Struct Mol Biol 17(6): 646-9 (2010)

Signal integration through blending, bolstering and bifurcating of intracellular information.
[20495562] Nat Struct Mol Biol 17(6): 653-8 (2010)

Theoretical considerations on the topological organization of receptor mosaics.
[19751189] Curr Protein Pept Sci 10(6): 559-69 (2009)

The Dynamical Systems Properties of the HOG Signaling Cascade.
[21637384] J Signal Transduct 2011(-): 930940 (2011)

Role of stromal-epithelial interactions in hormonal responses.
[15781983] Arch Histol Cytol 67(5): 417-34 (2004)

Membrane catalysis of peptide-receptor binding.
[20453923] Biochem Cell Biol 88(2): 203-10 (2010)

Quantitative understanding of cell signaling: the importance of membrane organization.
[20829029] Curr Opin Biotechnol 21(5): 677-82 (2010)

Computational modeling of mammalian signaling networks.
[20836022] Wiley Interdiscip Rev Syst Biol Med 2(2): 194-209 (2010)

Four-dimensional dynamics of MAPK information processing systems.
[20182652] Wiley Interdiscip Rev Syst Biol Med 1(1): 28-44 (2009)

Understanding the temporal codes of intra-cellular signals.
[20956081] Curr Opin Genet Dev 20(6): 684-93 (2010)

PROBING CANCER SIGNALING WITH RESONANT WAVEGUIDE GRATING BIOSENSORS.
[21113317] Expert Opin Drug Discov 5(12): 1237-1248 (2010)

Understanding signal integration through targeted mutations of an adapter protein.
[20965179] FEBS Lett 584(24): 4901-9 (2010)

Metabolism strikes back: metabolic flux regulates cell signaling.
[21159812] Genes Dev 24(24): 2717-22 (2010)

Chemical approaches towards unravelling kinase-mediated signalling pathways.
[21152652] Chem Soc Rev 40(3): 1211-23 (2011)

Reverse phase protein microarrays advance to use in clinical trials.
[20974554] Mol Oncol 4(6): 461-81 (2010)

The origin and dynamic evolution of chemical information transfer.
[21177681] Proc Biol Sci 278(1708): 970-9 (2011)

Intersecting pathways in cell biology.
[21156937] Sci Signal 3(152): re10 (2010)

A view into the blind spot: solution NMR provides new insights into signal transduction across the lipid bilayer.
[21134635] Structure 18(12): 1559-69 (2010)

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