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Intracellular transduction using cell-penetrating peptides Sawant R; Torchilin VMol Biosyst 2010[Apr]; 6 (4): 628-40Cell penetrating peptides (CPPs), TATp, in particular, has been used widely for intracellular delivery of various agents ranging from small molecules to proteins, peptides, range of pharmaceutical nanocarriers and imaging agents. This review highlights the mechanisms of CPP-mediated delivery and summarizes numerous examples illustrating the potential of CPPs in the fields of biology and medicine.|Amino Acid Sequence[MESH]|Animals[MESH]|Carrier Proteins/genetics/metabolism[MESH]|Cell Membrane/*metabolism[MESH]|Drug Delivery Systems[MESH]|Humans[MESH]|In Vitro Techniques[MESH]|Molecular Sequence Data[MESH]|Nanoparticles[MESH]|Nucleic Acids/genetics/metabolism[MESH]|Peptide Fragments/genetics/metabolism[MESH]|Protein Transport/genetics/*physiology[MESH]|Systems Biology[MESH]|Transduction, Genetic[MESH]|tat Gene Products, Human Immunodeficiency Virus/genetics/metabolism[MESH] |
