LE WE PMID CA
Vitamin D2894Vitamin D

1 alpha hydroxylase

1alpha dihydroxycholecalciferol

20 Epi 1 25 dihydroxyvitamin D3

25 hydroxycholecalciferol

Anabolic agents

Antiinflammatory compounds

Antineoplastic agents (Novel target ideas)

Asthma (BASKET)

Autophagy

B cell (Immunology)

BSPRY

CALB3

Calbindin D28k

Calbindin D9k

Calcium (Hypocalciemia)

Calcium (Physiology Intestines)

Calcium (Physiology renal)

Cardiovascular risk

CD36 FAT fatty acid translocase

Chemoprevention

Chromatin immunoprecipitation

Cinacalcet

Claudin12

Claudin17

Claudin2

COPD

Curcumin

CYP24A1 1 25 hydroxyvitamin d3 24 hydroxylase

Cyp24a1

CYP27B1 25OHD 1alpha hydroxylase

DBP

Diabetes mellitus (Involvement heart and vessels)

Docosahexaenoic acid

Eldecalcitol

ERS UFR (Pharmacology)

FGF23

Foam cell

GST pull down assay

Immunopharmacology

In vivo chromatin immunoprecipitation analysis

Innate immunity

Interleukin10

JNK

Kidney (Chronic renal failure)

Kidney (Intercalated cell)

Kidney (Osteopathy renal)

Kidney (Principal cells)

Kidney (Tubulus CCD)

Kidney (Tubulus CNT)

Kidney (Tubulus Distal Convoluted)

Kidney (Tubulus MCD)

Klotho

Lithocholic acid

LRP5 LDL Receptor Related Protein5 Arrow

Macrophages

Mammary gland (Neoplasia)

Npt2a

NPT2c

Osteocalcin

Osteopontin

Osteoporosis

PMCA1

Prostate (Anatomy)

Prostate (Neoplasia)

PTH (Hyperparathyreoidism secondary)

RANKL

Receptor (RXR)

Receptor (Vitamin D)

RelB

Runx2

Transporter (Sodium and phosphate)

TRPV5

TRPV6

Ussing chamber

Vitamin A

vitamin D dependent rickets1

Vitamin D dependent rickets2

Vitamin D

Vitamin D3 (Calcitriol)

Vitamin K

2010  
1
Hypovitaminosis D in hypertension.
[20622734] South Med J 103(8): 723-4 (2010)
2010  
2
Effects of vitamin D supplementation on blood pressure.
[20622727] South Med J 103(8): 729-37 (2010)
2008  
3
1alpha(OH)D3 One-alpha-hydroxy-cholecalciferol--an active vitamin D analog. Clinical studies on prophylaxis and treatment of secondary hyperparathyroidism in uremic patients on chronic dialysis.
[19232159] Dan Med Bull 55(4): 186-210 (2008)
2007  
4
Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials.
[17846391] Arch Intern Med 167(16): 1730-7 (2007)
2008  
5
2007  
6
SOLAR ultraviolet radiation and vitamin D: a historical perspective.
[17761571] Am J Public Health 97(10): 1746-54 (2007)
2010  
7
Vitamin D and cardiovascular prevention.
[20553279] Cardiovasc Ther 28(4): e5-12 (2010)
2008  
8
The complex role of vitamin D in autoimmune diseases.
[18510590] Scand J Immunol 68(3): 261-9 (2008)
2004  
9
Overview of general physiologic features and functions of vitamin D.
[15585789] Am J Clin Nutr 80(6 Suppl): 1689S-96S (2004)
2003  
10
Long-latency deficiency disease: insights from calcium and vitamin D.
[14594776] Am J Clin Nutr 78(5): 912-9 (2003)
1979  
11
The mechanism of action of vitamin D in the intestine.
[158978] Am J Clin Nutr 32(11): 2322-8 (1979)
1976  
12
Vitamin D, its metabolites and analogs: a review of the structural requirements for biological activity.
[187054] Am J Clin Nutr 29(11): 1271-82 (1976)
1995  
13
1,25(OH)2D3-regulated human keratinocyte proliferation and differentiation: basic studies and their clinical application.
[7782932] J Nutr 125(6 Suppl): 1709S-1714S (1995)
1995  
14
Immunosuppressive actions of 1,25-dihydroxyvitamin D3: preferential inhibition of Th1 functions.
[7782931] J Nutr 125(6 Suppl): 1704S-1708S (1995)
1995  
15
Nongenomic effects of 1,25-dihydroxyvitamin D3: potential relation of a plasmalemmal receptor to the acute enhancement of intestinal calcium transport in chick.
[7782929] J Nutr 125(6 Suppl): 1695S-1698S (1995)
1995  
16
Genomic actions of 1,25-dihydroxyvitamin D3.
[7782928] J Nutr 125(6 Suppl): 1690S-1694S (1995)
1995  
17
Pleiotropic Actions of 1 alpha, 25-dihydroxyvitamin D3: an overview.
[7782927] J Nutr 125(6 Suppl): 1687S-1689S (1995)
1990  
18
The use and interpretation of assays for vitamin D and its metabolites.
[2243289] J Nutr 120 Suppl 11(-): 1464-9 (1990)
2009  
19
Vitamin D and the cardiovascular system.
[19696220] Clin J Am Soc Nephrol 4(9): 1515-22 (2009)
2009  
20
Clinical outcomes with active versus nutritional vitamin D compounds in chronic kidney disease.
[19661219] Clin J Am Soc Nephrol 4(9): 1529-39 (2009)
2009  
21
Treatment of secondary hyperparathyroidism in CKD patients with cinacalcet and/or vitamin D derivatives.
[19056615] Clin J Am Soc Nephrol 4(1): 234-41 (2009)
2008  
22
2010  
23
Control of secondary hyperparathyroidism by vitamin D receptor agonists in chronic kidney disease.
[20133492] Clin J Am Soc Nephrol 5(3): 512-8 (2010)
1982  
24
Vitamin D metabolism and its clinical application.
[6754741] J Bone Joint Surg Br 64(5): 542-60 (1982)
2006  
25
Promise of vitamin D analogues in the treatment of hyperproliferative conditions.
[16648549] Mol Cancer Ther 5(4): 797-808 (2006)
2004  
26
Calcitriol in cancer treatment: from the lab to the clinic.
[15026558] Mol Cancer Ther 3(3): 373-81 (2004)
1998  
27
Current understanding of the molecular actions of vitamin D.
[9790574] Physiol Rev 78(4): 1193-231 (1998)
2008  
28
Vitamin D and human health: lessons from vitamin D receptor null mice.
[18694980] Endocr Rev 29(6): 726-76 (2008)
2005  
29
Noncalcemic actions of vitamin D receptor ligands.
[15798098] Endocr Rev 26(5): 662-87 (2005)
2005  
30
2007  
31
Meta-analysis: vitamin D compounds in chronic kidney disease.
[18087055] Ann Intern Med 147(12): 840-53 (2007)
1993  
32
Calcitriol: the major humoral mediator of hypercalcemia in Hodgkin's disease and non-Hodgkin's lymphomas.
[8364192] Blood 82(5): 1383-94 (1993)
2007  
33
Vitamin D, osteoclastogenesis and bone resorption: from mechanistic insight to the development of new analogs.
[16960400] Endocr J 54(1): 1-6 (2007)
1998  
34
24,25-Dihydroxyvitamin D--active metabolite or inactive catabolite?
[9681484] Endocrinology 139(8): 3371-4 (1998)
2009  
35
2006  
36
Resurrection of vitamin D deficiency and rickets.
[16886050] J Clin Invest 116(8): 2062-72 (2006)
1985  
37
1997  
38
The vitamin D hormone and its nuclear receptor: molecular actions and disease states.
[9379138] J Endocrinol 154 Suppl(-): S57-73 (1997)
1995  
39
Recent progress in enzymology and molecular biology of enzymes involved in vitamin D metabolism.
[7595086] J Lipid Res 36(8): 1641-52 (1995)
2000  
40
1alpha-Hydroxylase and the action of vitamin D.
[11013342] J Mol Endocrinol 25(2): 141-8 (2000)
2002  
41
Update on vitamin D and its newer analogues: actions and rationale for treatment in chronic renal failure.
[12109997] Kidney Int 62(2): 367-74 (2002)
1999  
42
Parathyroid hormone, vitamin D, and cardiovascular disease in chronic renal failure.
[10432376] Kidney Int 56(2): 383-92 (1999)
2001  
43
Vitamin D analogues: how do they differ and what is their clinical role?
[11572878] Nephrol Dial Transplant 16(10): 1965-7 (2001)
2000  
44
What's new in vitamin D for the nephrologist?
[10727539] Nephrol Dial Transplant 15(4): 460-6 (2000)
2000  
45
Management of disturbed calcium metabolism in uraemic patients: 1. Use of vitamin D metabolites.
[11073270] Nephrol Dial Transplant 15 Suppl 5(-): 18-24 (2000)
1999  
46
Importance of vitamin D repletion in uraemia.
[10328449] Nephrol Dial Transplant 14(4): 819-23 (1999)
2008  
47
Vitamin D deficiency in children and its management: review of current knowledge and recommendations.
[18676559] Pediatrics 122(2): 398-417 (2008)
1979  
48
Vitamin D deficient states. Pathophysiology and treatment.
[388869] West J Med 131(4): 305-12 (1979)
1974  
49
Metabolism and action of the hormone vitamin D. Its relation to diseases of calcium homeostasis.
[4365934] West J Med 121(1): 22-44 (1974)
1994  
50
The biological action of calcitriol in renal failure.
[7996783] Kidney Int 46(3): 605-12 (1994)
1991  
51
Vitamin D and calcium transport.
[1662321] Kidney Int 40(6): 1177-89 (1991)
1986  
52
The metabolism and mechanism of action of 1,25-dihydroxyvitamin D3.
[3029498] Kidney Int 30(6): 793-803 (1986)
1973  
53
Treatment of renal osteodystrophy with calciferol (vitamin D) and related steroids.
[4364427] Kidney Int 4(2): 161-7 (1973)
1972  
54
Editorial: Vitamin D, the kidney and calcium homeostasis.
[4365818] Kidney Int 2(5): 241-6 (1972)
2001  
55
Cytochrome P450 enzymes in the bioactivation of vitamin D to its hormonal form (review).
[11172626] Int J Mol Med 7(2): 201-9 (2001)
2008  
56
The physiology of vitamin D : current concepts.
[18497440] Indian J Med Res 127(3): 256-62 (2008)
2011  
57
Factors influencing vitamin D status.
[21384086] Acta Derm Venereol 91(2): 115-24 (2011)
2009  
58
Vitamin D status: measurement, interpretation, and clinical application.
[18329892] Ann Epidemiol 19(2): 73-8 (2009)
2010  
59
Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy.
[21155624] Altern Med Rev 15(3): 199-222 (2010)
2008  
60
2010  
61
The complexities of vitamin D.
[20439558] Cleve Clin J Med 77(5): 288 (2010)
2008  
62
Prevention of rickets and vitamin D deficiency in infants, children, and adolescents.
[18977996] Pediatrics 122(5): 1142-52 (2008)
2009  
63
Vitamin D deficiency in children with chronic kidney disease: uncovering an epidemic.
[19255004] Pediatrics 123(3): 791-6 (2009)
2010  
64
Vitamin D deficiency in adults: when to test and how to treat.
[20675513] Mayo Clin Proc 85(8): 752-7; quiz 757-8 (2010)
2006  
65
High prevalence of vitamin D inadequacy and implications for health.
[16529140] Mayo Clin Proc 81(3): 353-73 (2006)
2011  
66
2010  
67
Vitamin D and hypertension: current evidence and future directions.
[20937970] Hypertension 56(5): 774-9 (2010)
2009  
68
The survival advantage for haemodialysis patients taking vitamin D is questioned: findings from the Dialysis Outcomes and Practice Patterns Study.
[19028748] Nephrol Dial Transplant 24(3): 963-72 (2009)
2009  
69
Association of oral calcitriol with improved survival in non-dialysed and dialysed patients with CKD.
[18997163] Nephrol Dial Transplant 24(2): 341-4 (2009)
2009  
70
Mortality reduction by vitamin D receptor activation in end-stage renal disease: a commentary on the robustness of current data.
[18768581] Nephrol Dial Transplant 24(3): 703-6 (2009)
2008  
71
Use (or misuse) of vitamin D treatment in CKD and dialysis patients: A recent meta-analysis on vitamin D compounds in chronic kidney disease [1] and an editorial comment [2] accompanying this meta-analysis have already been published. We believe that these papers deserve some comments in the interest of the NDT readership.
[18400819] Nephrol Dial Transplant 23(6): 1786-9; discussion 1789-3 (2008)
2010  
72
Vitamin D insufficiency, deficiency, and bone health.
[20525913] J Clin Endocrinol Metab 95(6): 2630-3 (2010)
2010  
73
2009  
74
2010  
75
2010  
76
Assessment and interpretation of circulating 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in the clinical environment.
[20511051] Endocrinol Metab Clin North Am 39(2): 271-86, table of contents (2010)
2009  
77
Vitamin D for treatment and prevention of infectious diseases: a systematic review of randomized controlled trials.
[19491064] Endocr Pract 15(5): 438-49 (2009)
2010  
78
Cholecalciferol loading dose guideline for vitamin D-deficient adults.
[20139241] Eur J Endocrinol 162(4): 805-11 (2010)
2011  
79
Vitamin D, vitamin D receptor, and macroautophagy in inflammation and infection.
[21524386] Discov Med 11(59): 325-35 (2011)
2009  
80
Potential for vitamin D receptor agonists in the treatment of cardiovascular disease.
[19371337] Br J Pharmacol 158(2): 395-412 (2009)
2002  
81
Regulation of renin expression and blood pressure by vitamin D(3).
[12122105] J Clin Invest 110(2): 155-6 (2002)
2008  
82
Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction?
[18056830] FASEB J 22(4): 982-1001 (2008)
2010  
83
The role of vitamin D in regulating immune responses.
[20684184] Isr Med Assoc J 12(3): 174-5 (2010)
2009  
84
Vitamin D beyond bones in chronic obstructive pulmonary disease: time to act.
[19164701] Am J Respir Crit Care Med 179(8): 630-6 (2009)
2010  
85
Evidence-based non-skeletal actions of vitamin D.
[20485898] Arq Bras Endocrinol Metabol 54(2): 110-7 (2010)
2011  
86
Short-term effects of high-dose oral vitamin D3 in critically ill vitamin D deficient patients: a randomized, double-blind, placebo-controlled pilot study.
[21443793] Crit Care 15(2): R104 (2011)
2009  
87
The vitamin D-antimicrobial peptide pathway and its role in protection against infection.
[19895218] Future Microbiol 4(9): 1151-65 (2009)
2010  
88
Role of vitamin D in cardiovascular disease.
[20308705] Neth J Med 68(3): 113-8 (2010)
2010  
89
Vitamin D and the intracrinology of innate immunity.
[20156523] Mol Cell Endocrinol 321(2): 103-11 (2010)
2010  
90
Reciprocal control of 1,25-dihydroxyvitamin D and FGF23 formation involving the FGF23/Klotho system.
[20798257] Clin J Am Soc Nephrol 5(9): 1717-22 (2010)
2010  
91
Fibroblast growth factor 23 and disordered vitamin D metabolism in chronic kidney disease: updating the "trade-off" hypothesis.
[20507957] Clin J Am Soc Nephrol 5(9): 1710-6 (2010)
2010  
92
Survival benefits with vitamin D receptor activation: new insights since 2003.
[20507950] Clin J Am Soc Nephrol 5(9): 1704-9 (2010)
2008  
93
Vitamin effects on the immune system: vitamins A and D take centre stage.
[19172691] Nat Rev Immunol 8(9): 685-98 (2008)
2009  
94
Role of vitamin D in chronic kidney disease.
[19371802] Semin Nephrol 29(2): 113-21 (2009)
2007  
95
Factors that influence the cutaneous synthesis and dietary sources of vitamin D.
[17254541] Arch Biochem Biophys 460(2): 213-7 (2007)
2007  
96
An architectural perspective of vitamin D responsiveness.
[17288986] Arch Biochem Biophys 460(2): 293-9 (2007)
2007  
97
Vitamin D receptor-mediated suppression of RelB in antigen presenting cells: a paradigm for ligand-augmented negative transcriptional regulation.
[17367745] Arch Biochem Biophys 460(2): 218-26 (2007)
2002  
98
Mechanisms implicated in the growth regulatory effects of vitamin D in breast cancer.
[11914182] Endocr Relat Cancer 9(1): 45-59 (2002)
2010  
99
Molecular pathways mediating the anti-inflammatory effects of calcitriol: implications for prostate cancer chemoprevention and treatment.
[19926709] Endocr Relat Cancer 17(1): R19-38 (2010)
2009  
100
1,25(OH)2 vitamin d inhibits foam cell formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus.
[19667238] Circulation 120(8): 687-98 (2009)
2010  
101
Vitamin D: newly discovered actions require reconsideration of physiologic requirements.
[20149679] Trends Endocrinol Metab 21(6): 375-84 (2010)
2009  
102
Human duodenum responses to vitamin D metabolites of TRPV6 and other genes involved in calcium absorption.
[19779013] Am J Physiol Gastrointest Liver Physiol 297(6): G1193-7 (2009)
2002  
103
Vitamin D-inducible calcium transport and gene expression in three Caco-2 cell lines.
[12181175] Am J Physiol Gastrointest Liver Physiol 283(3): G618-25 (2002)
2009  
104
The enhanced hypercalcemic response to 20-epi-1,25-dihydroxyvitamin D3 results from a selective and prolonged induction of intestinal calcium-regulating genes.
[19423758] Endocrinology 150(8): 3448-56 (2009)
2006  
105
Identification of BSPRY as a novel auxiliary protein inhibiting TRPV5 activity.
[16380433] J Am Soc Nephrol 17(1): 26-30 (2006)
2005  
106
Hypervitaminosis D mediates compensatory Ca2+ hyperabsorption in TRPV5 knockout mice.
[16148038] J Am Soc Nephrol 16(11): 3188-95 (2005)
2003  
107
Localization and regulation of the epithelial Ca2+ channel TRPV6 in the kidney.
[14569082] J Am Soc Nephrol 14(11): 2731-40 (2003)
2007  
108
Characterizing early events associated with the activation of target genes by 1,25-dihydroxyvitamin D3 in mouse kidney and intestine in vivo.
[17556365] J Biol Chem 282(31): 22344-52 (2007)
2010  
109
Mechanisms involved in vitamin D mediated intestinal calcium absorption and in non-classical actions of vitamin D.
[20214989] J Steroid Biochem Mol Biol 121(1-2): 183-7 (2010)
2007  
110
Perspectives on mechanisms of gene regulation by 1,25-dihydroxyvitamin D3 and its receptor.
[17223545] J Steroid Biochem Mol Biol 103(3-5): 389-95 (2007)
2005  
111
Large-scale in silico and microarray-based identification of direct 1,25-dihydroxyvitamin D3 target genes.
[16002434] Mol Endocrinol 19(11): 2685-95 (2005)
2012  
112
Fibroblast growth factor-23 abolishes 1,25-dihydroxyvitamin D(3)-enhanced duodenal calcium transport in male mice.
[22275752] Am J Physiol Endocrinol Metab 302(8): E903-13 (2012)
2007  
113
Vitamin D: molecular mechanism of action.
[18083936] Ann N Y Acad Sci 1116(): 340-8 (2007)
2012  
114
Molecular Mechanisms of Vitamin D Action.
[22782502] Calcif Tissue Int (): (2012)
2011  
115
The vitamin D analog 1alpha,25-Dihydroxy-2beta-(3-Hydroxypropyloxy) vitamin D(3) (Eldecalcitol) is a potent regulator of calcium and phosphate metabolism.
[21912832] Calcif Tissue Int 89(5): 372-8 (2011)
2008  
116
1,25-dihydroxyvitamin D(3) promotes IL-10 production in human B cells.
[18651709] Eur J Immunol 38(8): 2210-8 (2008)
2003  
117
New insights into the mechanisms of vitamin D action.
[12577303] J Cell Biochem 88(4): 695-705 (2003)
2007  
118
Low-calcemic, highly antiproliferative, 23-oxa ether analogs of the natural hormone 1 alpha,25-dihydroxyvitamin D3: design, synthesis, and preliminary biological evaluation.
[17924616] J Med Chem 50(23): 5824-32 (2007)
2007  
119
1,25-Dihydroxyvitamin D3/VDR-mediated induction of FGF23 as well as transcriptional control of other bone anabolic and catabolic genes that orchestrate the regulation of phosphate and calcium mineral metabolism.
[17293108] J Steroid Biochem Mol Biol 103(3-5): 381-8 (2007)
2007  
120
The effects of Vitamin D metabolites on expression of genes for calcium transporters in human duodenum.
[17204416] J Steroid Biochem Mol Biol 103(3-5): 509-12 (2007)
2007  
121
Differential effects of Vitamin D analogs on calcium transport.
[17046242] J Steroid Biochem Mol Biol 103(1): 84-9 (2007)
2004  
122
Effects of vitamin D compounds on renal and intestinal Ca2+ transport proteins in 25-hydroxyvitamin D3-1alpha-hydroxylase knockout mice.
[15327402] Kidney Int 66(3): 1082-9 (2004)
2011  
123
TRPV6 determines the effect of vitamin D3 on prostate cancer cell growth.
[21347289] PLoS One 6(2): e16856 (2011)
2002  
124
Differential effects of 19-nor-1,25-dihydroxyvitamin D(2) and 1,25-dihydroxyvitamin D(3) on intestinal calcium and phosphate transport.
[12032488] J Lab Clin Med 139(5): 279-84 (2002)
2009  
125
Vitamin D: an evidence-based review.
[19897699] J Am Board Fam Med 22(6): 698-706 (2009)
2010  
126
The importance of vitamin D levels in autoimmune diseases.
[21125142] Rev Bras Reumatol 50(1): 67-80 (2010)
2010  
127
Benefit-risk assessment of vitamin D supplementation.
[19957164] Osteoporos Int 21(7): 1121-32 (2010)
2009  
128
Vitamin D and non-Hodgkin lymphoma risk in adults: a review.
[19832043] Cancer Invest 27(9): 942-51 (2009)
2011  
129
Optimal use of vitamin D when treating osteoporosis.
[21113692] Curr Osteoporos Rep 9(1): 36-42 (2011)
2008  
130
Unexpected actions of vitamin D: new perspectives on the regulation of innate and adaptive immunity.
[18212810] Nat Clin Pract Endocrinol Metab 4(2): 80-90 (2008)
2006  
131
2006  
132
2006  
133
Molecular regulation of calcium and bone metabolism through the vitamin D receptor.
[17185813] J Musculoskelet Neuronal Interact 6(4): 336-7 (2006)
2006  
134
2002  
135
Antiproliferative effects of 1,25-dihydroxyvitamin D3 on breast cells: a mini review.
[11743608] Braz J Med Biol Res 35(1): 1-9 (2002)
2008  
136
The vitamin D deficiency pandemic and consequences for nonskeletal health: mechanisms of action.
[18801384] Mol Aspects Med 29(6): 361-8 (2008)
2010  
137
Vitamin D and molecular actions on the immune system: modulation of innate and autoimmunity.
[20119827] J Mol Med (Berl) 88(5): 441-50 (2010)
2009  
138
Childhood asthma may be a consequence of vitamin D deficiency.
[19365260] Curr Opin Allergy Clin Immunol 9(3): 202-7 (2009)

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