Leptin

Leptin: a diverse regulator of neuronal function.
[17076761] J Neurochem 100(2): 307-13 (2007)

Role of leptin in immunity.
[17349207] Cell Mol Immunol 4(1): 1-13 (2007)

The intricate interface between immune and metabolic regulation: a role for leptin in the pathogenesis of multiple sclerosis?
[18552206] J Leukoc Biol 84(4): 893-9 (2008)

Leptin in the regulation of immunity, inflammation, and hematopoiesis.
[11037963] J Leukoc Biol 68(4): 437-46 (2000)

Leptin: a pivotal regulator of human energy homeostasis.
[19211814] Am J Clin Nutr 89(3): 980S-984S (2009)

From observation to experimentation: leptin action in the mediobasal hypothalamus.
[19176744] Am J Clin Nutr 89(3): 985S-990S (2009)

Leptin in humans: lessons from translational research.
[19176740] Am J Clin Nutr 89(3): 991S-997S (2009)

Leptin signaling in the central nervous system and the periphery.
[14749508] Recent Prog Horm Res 59(-): 305-31 (2004)

Leptin receptor signaling and the regulation of mammalian physiology.
[14749507] Recent Prog Horm Res 59(-): 287-304 (2004)

Insulin and leptin as adiposity signals.
[14749506] Recent Prog Horm Res 59(-): 267-85 (2004)

The use of animal models to dissect the biology of leptin.
[14749505] Recent Prog Horm Res 59(-): 245-66 (2004)

Leptin and the cardiovascular system.
[14749504] Recent Prog Horm Res 59(-): 225-44 (2004)

Leptin controls bone formation through a hypothalamic relay.
[11237223] Recent Prog Horm Res 56(-): 401-15 (2001)

Leptin: a multifunctional hormone.
[10896170] Cell Res 10(2): 81-92 (2000)

The role of leptin in innate and adaptive immune responses.
[16879738] Arthritis Res Ther 8(5): 217 (2006)

The adipoinsular axis: effects of leptin on pancreatic beta-cells.
[10644531] Am J Physiol Endocrinol Metab 278(1): E1-E14 (2000)

The role of leptin in human obesity and disease: a review of current evidence.
[10215564] Ann Intern Med 130(8): 671-80 (1999)

Intracellular signalling pathways activated by leptin.
[16336196] Biochem J 393(Pt 1): 7-20 (2006)

Clinical review 94: What's in a name? In search of leptin's physiologic role.
[9589630] J Clin Endocrinol Metab 83(5): 1407-13 (1998)

Towards a pro-inflammatory and immunomodulatory emerging role of leptin.
[16720637] Rheumatology (Oxford) 45(8): 944-50 (2006)

Integration of hormonal and nutrient signals that regulate leptin synthesis and secretion.
[19318513] Am J Physiol Endocrinol Metab 296(6): E1230-8 (2009)

Recent advances in understanding leptin signaling and leptin resistance.
[19724019] Am J Physiol Endocrinol Metab 297(6): E1247-59 (2009)

Leptin and cardiovascular disease: response to therapeutic interventions.
[18574061] Circulation 117(25): 3238-49 (2008)

Sleep-related hypoventilation: the evolving role of leptin.
[16162684] Chest 128(3): 1079-81 (2005)

Leptin signaling and obesity: cardiovascular consequences.
[17872473] Circ Res 101(6): 545-59 (2007)

Leptin-induced cardiac hypertrophy: RhoAing a lipid raft down a protective p38 MAPK signalling stream?
[18006446] Cardiovasc Res 77(1): 4-5 (2008)

Neuropeptide Y in normal eating and in genetic and dietary-induced obesity.
[16874931] Philos Trans R Soc Lond B Biol Sci 361(1471): 1159-85 (2006)

Appetite and energy balance signals from adipocytes.
[16815801] Philos Trans R Soc Lond B Biol Sci 361(1471): 1237-49 (2006)

Genetic causes of human reproductive disease.
[12050198] J Clin Endocrinol Metab 87(6): 2447-54 (2002)

Clinical review 148: Monogenic disorders of puberty.
[12050203] J Clin Endocrinol Metab 87(6): 2481-94 (2002)

The central regulation of bone mass, the first link between bone remodeling and energy metabolism.
[21051575] J Clin Endocrinol Metab 95(11): 4795-801 (2010)

Adipocytokines and the metabolic complications of obesity.
[18987272] J Clin Endocrinol Metab 93(11 Suppl 1): S64-73 (2008)

Whither recombinant human leptin treatment for HIV-associated lipoatrophy and the metabolic syndrome?
[19349474] J Clin Endocrinol Metab 94(4): 1089-91 (2009)

Roles of FoxO1 and Sirt1 in the central regulation of food intake.
[21048357] Endocr J 57(11): 939-46 (2010)

Hypothalamic leptin regulation of energy homeostasis and glucose metabolism.
[17584844] J Physiol 583(Pt 2): 437-43 (2007)

Sixteen years and counting: an update on leptin in energy balance.
[21633176] J Clin Invest 121(6): 2087-93 (2011)

Central nervous system regulation of energy metabolism: ghrelin versus leptin.
[18448790] Ann N Y Acad Sci 1126(-): 14-9 (2008)

Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin.
[15265818] Clin Chem 50(9): 1511-25 (2004)

The PI3K signaling pathway mediates the biological effects of leptin.
[21085763] Arq Bras Endocrinol Metabol 54(7): 591-602 (2010)

Role of leptin in obesity-related hypertension.
[16105937] Exp Physiol 90(5): 683-8 (2005)

The role of leptin-melanocortin system and human weight regulation: lessons from experiments of nature.
[19221669] Ann Acad Med Singapore 38(1): 34-11 (2009)

Role of leptin in the activation of immune cells.
[20368778] Mediators Inflamm 2010(-): 568343 (2010)

Leptin and the control of metabolism: role for stearoyl-CoA desaturase-1 (SCD-1).
[15333742] J Nutr 134(9): 2455S-2463S (2004)

The leptin hypothesis of depression: a potential link between mood disorders and obesity?
[18032111] Curr Opin Pharmacol 7(6): 648-52 (2007)

Role of CRF and other neuropeptides in stress-induced reinstatement of drug seeking.
[19631614] Brain Res 1314(-): 15-28 (2010)

Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity.
[18854155] Cell 135(1): 61-73 (2008)

Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol.
[21983012] Cell Signal 24(2): 484-92 (2012)

Leptin and the control of body weight: a review of its diverse central targets, signaling mechanisms, and role in the pathogenesis of obesity.
[19644451] Obesity (Silver Spring) 18(2): 221-9 (2010)

Leptin receptor signaling and action in the central nervous system.
[17021368] Obesity (Silver Spring) 14 Suppl 5(-): 208S-212S (2006)

Leptin resistance and the response to positive energy balance.
[18508097] Physiol Behav 94(5): 660-3 (2008)

Molecular and neural mediators of leptin action.
[18501391] Physiol Behav 94(5): 637-42 (2008)

Hypothalamic substrates of metabolic imprinting.
[18262209] Physiol Behav 94(1): 79-89 (2008)

Narrative review: the role of leptin in human physiology: emerging clinical applications.
[20083828] Ann Intern Med 152(2): 93-100 (2010)

The role of leptin in the respiratory system: an overview.
[21040518] Respir Res 11(-): 152 (2010)

Leptin receptor signaling and the regulation of mammalian physiology.
[19136996] Int J Obes (Lond) 32 Suppl 7(-): S8-12 (2008)

Central leptin receptor action and resistance in obesity.
[20029269] J Investig Med 57(7): 789-94 (2009)

Leptin in human physiology and therapeutics.
[20600241] Front Neuroendocrinol 31(3): 377-93 (2010)

Hypothalamic control of lipid metabolism: focus on leptin, ghrelin and melanocortins.
[21576929] Neuroendocrinology 94(1): 1-11 (2011)

Hypothalamic sites of leptin action linking metabolism and reproduction.
[21099209] Neuroendocrinology 93(1): 9-18 (2011)

Hypothalamic regulation of bone.
[20660619] J Mol Endocrinol 45(4): 175-81 (2010)

AMPK as a mediator of hormonal signalling.
[19625456] J Mol Endocrinol 44(2): 87-97 (2010)

Central leptin insufficiency syndrome: an interactive etiology for obesity, metabolic and neural diseases and for designing new therapeutic interventions.
[18053615] Peptides 29(1): 127-38 (2008)

Leptin resistance: a prediposing factor for diet-induced obesity.
[19091915] Am J Physiol Regul Integr Comp Physiol 296(3): R493-500 (2009)

Insulin, leptin, and food reward: update 2008.
[18945945] Am J Physiol Regul Integr Comp Physiol 296(1): R9-R19 (2009)

Leptin: at the crossroads of energy balance and systemic inflammation.
[17275915] Prog Lipid Res 46(2): 89-107 (2007)

Disruption in the leptin-NPY link underlies the pandemic of diabetes and metabolic syndrome: new therapeutic approaches.
[18725078] Nutrition 24(9): 820-6 (2008)

The procognitive effects of leptin in the brain and their clinical implications.
[21070531] Int J Clin Pract 64(13): 1808-12 (2010)

Leptin in hepatocellular carcinoma.
[21155000] World J Gastroenterol 16(46): 5801-9 (2010)

FTO contributes to hepatic metabolism regulation through regulation of leptin action and STAT3 signalling in liver.
[24410832] Cell Commun Signal 12():4 (2014)

Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis.
[23207144] J Hepatol 58(4):778-84 (2013)

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