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  • Leptin in immunology
  • Matarese G; Moschos S; Mantzoros CS
  • J Immunol 2005[Mar]; 174 (6): 3137-42
  • Leptin is an adipokine which conveys information on energy availability. In humans, leptin influences energy homeostasis and regulates neuroendocrine function primarily in states of energy deficiency. As a cytokine, leptin also affects thymic homeostasis and, similar to other proinflammatory cytokines, leptin promotes Th1 cell differentiation and cytokine production. We review herein recent advances on the role of leptin in the pathophysiology of immune responses.
  • |Adipose Tissue/immunology/metabolism[MESH]
  • |Animals[MESH]
  • |Autoimmunity[MESH]
  • |Energy Metabolism[MESH]
  • |Humans[MESH]
  • |Immunity, Innate[MESH]
  • |Infections/etiology/immunology[MESH]
  • |Inflammation/etiology/immunology[MESH]
  • |Leptin/*immunology[MESH]
  • |Models, Immunological[MESH]
  • |Signal Transduction[MESH]

  • *{{pmid15749839}}
    *<b>[ Leptin in immunology ]</b> J Immunol 2005; 174(6) ; 3137-42 Matarese G; Moschos S; Mantzoros CS


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    J Immunol

    3137 6.174 2005