LE WE PMID CA
beta cell (Pancreas)354beta Zelle (Pankreas)

Amylin

beta cell (Pancreas)

Calcium (Intracellular)

Cdkal1

Cell secretion (Granule secretion)

Coronin3

Diabetes mellitus (BASKET)

Diabetes mellitus T2DM (Type2)

Epac2

ERp46

GIP glucose dependent insulinotropic polypeptide

Glucose (Hyperglycemia)

IAPP islet amyloid polypeptide

Insulin (BASKET)

Ion channel (Potassium)

Ion channel (TRP Family)

KATP

Lipotoxicity

Munc18c

Neurogenin3

NOD mouse

Nrf2

Osteopontin

PDX1

Phosphatidylethanolamine

Protein (ptm Carboxylmethylation)

RAB27A

Regeneration of tissues and other biologic structures

RNA (MicroRNA)

RNA (tRNA)

SIRT1

SNAP23

SNAP25

Syntaxin

TRPV4

VAMP

2009  
1
Emerging roles for the ubiquitin-proteasome system and autophagy in pancreatic beta-cells.
[18812463] Am J Physiol Endocrinol Metab 296(1): E1-10 (2009)
2008  
2
Channel regulation of glucose sensing in the pancreatic beta-cell.
[18940941] Am J Physiol Endocrinol Metab 295(6): E1298-306 (2008)
2008  
3
Metabolic cycling in control of glucose-stimulated insulin secretion.
[18728221] Am J Physiol Endocrinol Metab 295(6): E1287-97 (2008)
2002  
4
The ryanodine receptor calcium channel of beta-cells: molecular regulation and physiological significance.
[11978625] Diabetes 51(5): 1299-309 (2002)
2002  
5
Metabolic oscillations in beta-cells.
[11815475] Diabetes 51 Suppl 1(-): S152-61 (2002)
2002  
6
Control mechanisms of the oscillations of insulin secretion in vitro and in vivo.
[11815474] Diabetes 51 Suppl 1(-): S144-51 (2002)
2002  
7
Clinical characterization of insulin secretion as the basis for genetic analyses.
[11815470] Diabetes 51 Suppl 1(-): S122-9 (2002)
2002  
8
Is reduced first-phase insulin release the earliest detectable abnormality in individuals destined to develop type 2 diabetes?
[11815469] Diabetes 51 Suppl 1(-): S117-21 (2002)
2002  
9
Phasic insulin release and metabolic regulation in type 2 diabetes.
[11815468] Diabetes 51 Suppl 1(-): S109-16 (2002)
2002  
10
Physiological consequences of phasic insulin release in the normal animal.
[11815467] Diabetes 51 Suppl 1(-): S103-8 (2002)
2002  
11
Triggering and augmentation mechanisms, granule pools, and biphasic insulin secretion.
[11815463] Diabetes 51 Suppl 1(-): S83-90 (2002)
2002  
12
A subset of 50 secretory granules in close contact with L-type Ca2+ channels accounts for first-phase insulin secretion in mouse beta-cells.
[11815462] Diabetes 51 Suppl 1(-): S74-82 (2002)
2002  
13
Beta-cell protein kinases and the dynamics of the insulin response to glucose.
[11815461] Diabetes 51 Suppl 1(-): S68-73 (2002)
2002  
14
Signals and pools underlying biphasic insulin secretion.
[11815460] Diabetes 51 Suppl 1(-): S60-7 (2002)
2002  
15
Modeling phasic insulin release: immediate and time-dependent effects of glucose.
[11815459] Diabetes 51 Suppl 1(-): S53-9 (2002)
2002  
16
Beta-cell mitochondria and insulin secretion: messenger role of nucleotides and metabolites.
[11815456] Diabetes 51 Suppl 1(-): S37-42 (2002)
2002  
17
Sulfonylurea-mediated stimulation of insulin exocytosis via an ATP-sensitive K+ channel-independent action.
[11815455] Diabetes 51 Suppl 1(-): S33-6 (2002)
2002  
18
Molecular determinants of regulated exocytosis.
[11815450] Diabetes 51 Suppl 1(-): S3-11 (2002)
2001  
19
Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus.
[11147773] Diabetes 50(1): 1-11 (2001)
2000  
20
Triggering and amplifying pathways of regulation of insulin secretion by glucose.
[11078440] Diabetes 49(11): 1751-60 (2000)
2008  
21
Synaptotagmins bind calcium to release insulin.
[18713958] Am J Physiol Endocrinol Metab 295(6): E1279-86 (2008)
2007  
22
Metabolic and electrical oscillations: partners in controlling pulsatile insulin secretion.
[17666486] Am J Physiol Endocrinol Metab 293(4): E890-900 (2007)
2007  
23
Assessment of beta-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests.
[17341552] Am J Physiol Endocrinol Metab 293(1): E1-E15 (2007)
2005  
24
Adenine nucleotide regulation in pancreatic beta-cells: modeling of ATP/ADP-Ca2+ interactions.
[15985450] Am J Physiol Endocrinol Metab 289(5): E839-48 (2005)
2005  
25
Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion.
[15585595] Am J Physiol Endocrinol Metab 288(1): E1-15 (2005)
2004  
26
First-phase insulin secretion: does it exist in real life? Considerations on shape and function.
[15308473] Am J Physiol Endocrinol Metab 287(3): E371-85 (2004)
2002  
27
Phosphorylated inositol compounds in beta -cell stimulus-response coupling.
[12424101] Am J Physiol Endocrinol Metab 283(6): E1113-22 (2002)
2004  
28
Pathways in beta-cell stimulus-secretion coupling as targets for therapeutic insulin secretagogues.
[15561921] Diabetes 53 Suppl 3(): S48-58 (2004)
2004  
29
Five stages of evolving beta-cell dysfunction during progression to diabetes.
[15561905] Diabetes 53 Suppl 3(): S16-21 (2004)
2002  
30
Regulation of pancreatic beta-cell glucokinase: from basics to therapeutics.
[12475782] Diabetes 51 Suppl 3(): S394-404 (2002)
2002  
31
Stimulus/secretion coupling factors in glucose-stimulated insulin secretion: insights gained from a multidisciplinary approach.
[12475781] Diabetes 51 Suppl 3(): S389-93 (2002)
2002  
32
The succinate mechanism of insulin release.
[12196457] Diabetes 51(9): 2669-76 (2002)
2006  
33
Transcription factors regulating beta-cell function.
[17062882] Eur J Endocrinol 155(5): 671-9 (2006)
2007  
34
Molecular regulation of pancreatic beta-cell mass development, maintenance, and expansion.
[17293440] J Mol Endocrinol 38(1-2): 193-206 (2007)
2010  
35
Electrical bursting, calcium oscillations, and synchronization of pancreatic islets.
[20217502] Adv Exp Med Biol 654(-): 261-79 (2010)
2010  
36
Bursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.
[20628025] Am J Physiol Endocrinol Metab 299(4): E517-32 (2010)
2010  
37
Glucolipotoxicity of the pancreatic beta cell.
[19715772] Biochim Biophys Acta 1801(3): 289-98 (2010)
2011  
38
Rab27a, actin and beta-cell endocytosis.
[21187662] Endocr J 58(1): 1-6 (2011)
2011  
39
Functional loss of Cdkal1, a novel tRNA modification enzyme, causes the development of type 2 diabetes [Review].
[21908934] Endocr J 58(10): 819-25 (2011)
2010  
40
The role of blood vessels, endothelial cells, and vascular pericytes in insulin secretion and peripheral insulin action.
[20164242] Endocr Rev 31(3): 343-63 (2010)
2008  
41
Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis.
[18314421] Endocr Rev 29(3): 303-16 (2008)
2008  
42
Glucolipotoxicity: fuel excess and beta-cell dysfunction.
[18048763] Endocr Rev 29(3): 351-66 (2008)
2010  
43
The role of the KATP channel in glucose homeostasis in health and disease: more than meets the islet.
[20519313] J Physiol 588(Pt 17): 3201-9 (2010)
2008  
44
Novel aspects of the molecular mechanisms controlling insulin secretion.
[18511483] J Physiol 586(14): 3313-24 (2008)
2005  
45
Regulation of pancreatic beta-cell mass.
[16183912] Physiol Rev 85(4): 1255-70 (2005)
2010  
46
Pancreatic beta-cells: from generation to regeneration.
[20688184] Semin Cell Dev Biol 21(8): 838-44 (2010)
2007  
47
Physiological regulation of the pancreatic {beta}-cell: functional insights for understanding and therapy of diabetes.
[17272356] Exp Physiol 92(3): 481-96 (2007)
2010  
48
Pancreatic beta-cell signaling: toward better understanding of diabetes and its treatment.
[20551594] Proc Jpn Acad Ser B Phys Biol Sci 86(6): 563-77 (2010)
2009  
49
ERp46 is reduced by high glucose and regulates insulin content in pancreatic beta-cells.
[19622788] Am J Physiol Endocrinol Metab 297(3): E812-21 (2009)
2008  
50
Bridging the gap between protein carboxyl methylation and phospholipid methylation to understand glucose-stimulated insulin secretion from the pancreatic beta cell.
[17662254] Biochem Pharmacol 75(2): 335-45 (2008)
2011  
51
The role of thermosensitive TRP (transient receptor potential) channels in insulin secretion.
[21785227] Endocr J 58(12): 1021-8 (2011)
2011  
52
2008  
53
Calcium elevation in mouse pancreatic beta cells evoked by extracellular human islet amyloid polypeptide involves activation of the mechanosensitive ion channel TRPV4.
[18751967] Diabetologia 51(12): 2252-62 (2008)
2011  
54
Pleiotropic effects of GIP on islet function involve osteopontin.
[21810601] Diabetes 60(9): 2424-33 (2011)
2011  
55
MicroRNAs in β-cell biology, insulin resistance, diabetes and its complications.
[21709277] Diabetes 60(7): 1825-31 (2011)
2011  
56
Diabetes complications: the microRNA perspective.
[21709278] Diabetes 60(7): 1832-7 (2011)
2010  
57
Beta-cell growth and regeneration: replication is only part of the story.
[20876724] Diabetes 59(10): 2340-8 (2010)
2003  
58
Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection.
[12606496] Diabetes 52(3): 581-7 (2003)
2010  
59
Stress hypERactivation in the β-cell.
[21099287] Islets 2(1): 1-9 (2010)
2009  
60
Neurogenin3: a master regulator of pancreatic islet differentiation and regeneration.
[21099270] Islets 1(3): 177-84 (2009)
2009  
61
Endothelial cells in pancreatic islet development and function.
[21084843] Islets 1(1): 2-9 (2009)
2009  
62
Identification of a novel mechanism regulating β-cell mass: neuronal relay from the liver to pancreatic β-cells.
[21084852] Islets 1(1): 75-7 (2009)
2011  
63
Potential pathways to restore β-cell mass: pluripotent stem cells, reprogramming, and endogenous regeneration.
[21800022] Curr Diab Rep 11(5): 392-401 (2011)
2004  
64
Review: pancreatic beta-cell neogenesis revisited.
[15203882] Exp Diabesity Res 5(2): 111-21 (2004)
2009  
65
Pulsatility of insulin release--a clinically important phenomenon.
[19961265] Ups J Med Sci 114(4): 193-205 (2009)
2010  
66
Regulation of insulin secretion: role of mitochondrial signalling.
[20225132] Diabetologia 53(6): 1019-32 (2010)
2009  
67
The beta cell lesion in type 2 diabetes: there has to be a primary functional abnormality.
[19326096] Diabetologia 52(6): 1003-12 (2009)
2009  
68
Pdx1 and other factors that regulate pancreatic beta-cell survival.
[19817786] Diabetes Obes Metab 11 Suppl 4(-): 30-7 (2009)
2010  
69
Physiologic implications of phosphoinositides and phospholipase C in the regulation of insulin secretion.
[20354339] J Nutr Sci Vitaminol (Tokyo) 56(1): 1-8 (2010)
2010  
70
Epac2-dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1.
[21094904] Vitam Horm 84(-): 279-302 (2010)
2003  
71
Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes.
[12832692] Stem Cells 21(4): 377-88 (2003)
2010  
72
Minireview: beta-cell replacement therapy for diabetes in the 21st century: manipulation of cell fate by directed differentiation.
[20219891] Mol Endocrinol 24(8): 1501-11 (2010)
2010  
73
Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4.
[20053958] Am J Physiol Regul Integr Comp Physiol 298(3): R517-31 (2010)
2010  
74
ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function.
[19501608] Toxicol Appl Pharmacol 244(1): 77-83 (2010)
2010  
75
Leucine metabolism in regulation of insulin secretion from pancreatic beta cells.
[20500788] Nutr Rev 68(5): 270-9 (2010)
PMC   
76
Microenvironmental stimuli for proliferation of functional islet beta-cells.
[24594290] Cell Biosci 4(1):12 (2014)

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