Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Transcription factors regulating beta-cell function Cerf MEEur J Endocrinol 2006[Nov]; 155 (5): 671-9Type 2 diabetes is primarily associated with insulin resistance and beta-cell dysfunction. Maintenance of functional mature beta-cells is imperative for ensuring glucose homeostasis. This can be achieved by optimal expression of key transcription factors that are required for normal pancreatic development and maintaining beta-cell function. Defining the regulation of transcription factors as well as their regulation of important beta-cell genes like insulin will provide further insight into elucidating the mechanisms leading to beta-cell dysfunction.|Basic Helix-Loop-Helix Transcription Factors/physiology[MESH]|Eye Proteins/physiology[MESH]|Hepatocyte Nuclear Factor 1-alpha/physiology[MESH]|Hepatocyte Nuclear Factor 3-beta/physiology[MESH]|Homeodomain Proteins/physiology[MESH]|Humans[MESH]|Insulin-Secreting Cells/*physiology[MESH]|Maf Transcription Factors/physiology[MESH]|Nerve Tissue Proteins/physiology[MESH]|PAX6 Transcription Factor[MESH]|Paired Box Transcription Factors/physiology[MESH]|Pancreas/embryology[MESH]|Repressor Proteins/physiology[MESH]|Trans-Activators/physiology[MESH]|Transcription Factors/*physiology[MESH] |