LE WE PMID CA
Klotho1462Klotho

beta Glucuronidase

BSPRY

Calbindin D28k

Calbindin D9k

Calcium (Hypercalciuria)

Calcium (Physiology renal)

Claudin2

Curcumin

CYP27B1 25OHD 1alpha hydroxylase

Diabetes mellitus (Involvement kidney)

Docosahexaenoic acid

Endoglycosidase F

FGF23

Galectin1

Kallikrein

Kidney (Tubulus Distal Convoluted)

Kir1 1 ROMK

Klotho

Lithocholic acid

NCX1

NPT2c

Osteocalcin

Osteopontin

Phosphorous

Pro Urine

RANKL

Receptor (RXR)

Transporter (Sodium and phosphate)

TRPV5

TRPV6

Vitamin D

2006  
1
Klotho, an important new factor for the activity of Ca2+ channels, connecting calcium homeostasis, ageing and uraemia.
[16627600] Nephrol Dial Transplant 21(7): 1770-2 (2006)
2007  
2
Premature aging in klotho mutant mice: cause or consequence?
[17353153] Ageing Res Rev 6(1): 73-9 (2007)
2009  
3
Current understanding of klotho.
[19022406] Ageing Res Rev 8(1): 43-51 (2009)
2009  
4
2009  
5
Discovery of alpha-Klotho unveiled new insights into calcium and phosphate homeostasis.
[19282648] Proc Jpn Acad Ser B Phys Biol Sci 85(3): 125-41 (2009)
2009  
6
FGF23-mediated regulation of systemic phosphate homeostasis: is Klotho an essential player?
[19019915] Am J Physiol Renal Physiol 296(3): F470-6 (2009)
2010  
7
Reciprocal control of 1,25-dihydroxyvitamin D and FGF23 formation involving the FGF23/Klotho system.
[20798257] Clin J Am Soc Nephrol 5(9): 1717-22 (2010)
2009  
8
Klotho prevents renal calcium loss.
[19713312] J Am Soc Nephrol 20(11): 2371-9 (2009)
2008  
9
The beta-glucuronidase klotho exclusively activates the epithelial Ca2+ channels TRPV5 and TRPV6.
[18495742] Nephrol Dial Transplant 23(11): 3397-402 (2008)
2008  
10
Calcium and phosphate homeostasis: concerted interplay of new regulators.
[18293139] Ann Med 40(2): 82-91 (2008)
2007  
11
Concerted action of associated proteins in the regulation of TRPV5 and TRPV6.
[17233615] Biochem Soc Trans 35(Pt 1): 115-9 (2007)
2012  
12
Molecular Mechanisms of Vitamin D Action.
[22782502] Calcif Tissue Int (): (2012)
2012  
13
Characterization of vitamin D-deficient klotho-/- mice: do increased levels of serum 1,25(OH)2D3 cause disturbed calcium and phosphate homeostasis in klotho-/- mice?
[22778178] Nephrol Dial Transplant (): (2012)
2005  
14
The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel.
[16239475] Science 310(5747): 490-3 (2005)
2009  
15
Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho.
[19349416] Mol Pharmacol 76(1): 38-46 (2009)
2012  
16
Regulation of ion channels by secreted Klotho.
[22396165] Adv Exp Med Biol 728(): 100-6 (2012)
2007  
17
Regulation of the epithelial calcium channel TRPV5 by extracellular factors.
[17565273] Curr Opin Nephrol Hypertens 16(4): 319-24 (2007)
2006  
18
Klotho as a regulator of fibroblast growth factor signaling and phosphate/calcium metabolism.
[16775459] Curr Opin Nephrol Hypertens 15(4): 437-41 (2006)
2012  
19
Targeted Deletion of Klotho in Kidney Distal Tubule Disrupts Mineral Metabolism.
[22878961] J Am Soc Nephrol (): (2012)
2012  
20
Decreased renal alpha-Klotho expression in early diabetic nephropathy in humans and mice and its possible role in urinary calcium excretion.
[22217880] Kidney Int 81(6): 539-47 (2012)
2007  
21
Klotho: an antiaging protein involved in mineral and vitamin D metabolism.
[17332731] Kidney Int 71(8): 730-7 (2007)
2010  
22
2008  
23
Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1.
[18606998] Proc Natl Acad Sci U S A 105(28): 9805-10 (2008)
2010  
24
2011  
25
2011  
26
Klotho: an elixir of youth for the vasculature?
[21164022] J Am Soc Nephrol 22(1): 5-7 (2011)

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