Hedgehog

Hedgehog and patched in neural development and disease.
[9883719] Neuron 21(6): 1243-57 (1998)

Sonic Hedgehog signaling in the mammalian brain.
[20218977] J Neurochem 113(3): 576-90 (2010)

Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.
[20716670] Pharmacol Rev 62(3): 497-524 (2010)

Roughing up Smoothened: chemical modulators of hedgehog signaling.
[12437769] J Biol 1(2): 8 (2002)

The therapeutic potential of modulators of the Hedgehog-Gli signaling pathway.
[12437768] J Biol 1(2): 9 (2002)

Small-molecule modulators of the Sonic Hedgehog signaling pathway.
[20024066] Mol Biosyst 6(1): 44-54 (2010)

The hedgehog signaling pathway in cancer.
[17062662] Clin Cancer Res 12(20 Pt 1): 5924-8 (2006)

Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics.
[15958535] Cancer Res 65(12): 4975-8 (2005)

The hedgehog signalling pathway in tumorigenesis and development.
[10630637] Oncogene 18(55): 7844-51 (1999)

Hedgehog signaling pathway and gastric cancer.
[16258256] Cancer Biol Ther 4(10): 1050-4 (2005)

Actions of hedgehog proteins on skeletal cells.
[10634584] Crit Rev Oral Biol Med 10(4): 477-86 (1999)

Hedgehog signaling in development and homeostasis of the gastrointestinal tract.
[17928586] Physiol Rev 87(4): 1343-75 (2007)

Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface.
[14530294] Development 130(22): 5297-305 (2003)

Making a grade: Sonic Hedgehog signalling and the control of neural cell fate.
[19197245] EMBO J 28(5): 457-65 (2009)

Transducing Hedgehog: the story so far.
[9649421] EMBO J 17(13): 3505-11 (1998)

The role of kinases in the Hedgehog signalling pathway.
[18379584] EMBO Rep 9(4): 330-6 (2008)

Hedgehog: functions and mechanisms.
[18794343] Genes Dev 22(18): 2454-72 (2008)

Hedgehog signaling in animal development: paradigms and principles.
[11731473] Genes Dev 15(23): 3059-87 (2001)

The Hedgehog protein family.
[19040769] Genome Biol 9(11): 241 (2008)

New "hogs" in Hedgehog transport and signal reception.
[16678090] Cell 125(3): 435-8 (2006)

Transducing the hedgehog signal.
[11081624] Cell 103(3): 371-4 (2000)

More surprises in the Hedgehog signaling pathway.
[10660040] Cell 100(2): 185-8 (2000)

Hedgehog and Spitz: making a match between photoreceptor axons and their targets.
[9845360] Cell 95(5): 587-90 (1998)

Protein splicing of inteins and hedgehog autoproteolysis: structure, function, and evolution.
[9489693] Cell 92(1): 1-4 (1998)

The long and short of hedgehog signaling.
[7736584] Cell 81(3): 313-6 (1995)

Hedgehog and beyond.
[7867057] Cell 80(4): 517-20 (1995)

Sonic hedgehog: making the gradient.
[8807822] Chem Biol 3(1): 13-6 (1996)

Evidence for a novel feedback loop in the Hedgehog pathway involving Smoothened and Fused.
[17658259] Curr Biol 17(15): 1326-33 (2007)

Hedgehog signaling: measuring ligand concentrations with receptor ratios.
[15498480] Curr Biol 14(20): R889-91 (2004)

Hedgehog signaling: iguana debuts as a nuclear gatekeeper.
[15324687] Curr Biol 14(16): R668-70 (2004)

Sonic hedgehog regulates branching morphogenesis in the mammalian lung.
[9768363] Curr Biol 8(19): 1083-6 (1998)

Morphogenetic signalling. Responses to hedgehog.
[7552160] Curr Biol 5(6): 580-2 (1995)

Hedgehog signaling in development and cancer.
[19081070] Dev Cell 15(6): 801-12 (2008)

Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs.
[15736317] Dev Cell 8(2): 143-51 (2005)

Shifted from Wnt to Hedgehog signaling pathways.
[15694333] Mol Cell 17(3): 321-2 (2005)

The sonic hedgehog-patched-gli pathway in human development and disease.
[11001584] Am J Hum Genet 67(5): 1047-54 (2000)

A general role of hedgehog in the regulation of proliferation.
[17245127] Cell Cycle 6(2): 156-9 (2007)

Hedgehogs as negative regulators of the cell cycle.
[16082222] Cell Cycle 4(9): 1139-40 (2005)

Hedgehog morphogen in cardiovascular disease.
[17075024] Circulation 114(18): 1985-91 (2006)

How a Hedgehog might see holoprosencephaly.
[12668593] Hum Mol Genet 12 Spec No 1(-): R15-25 (2003)

Hedgehog signalling in endocrine development and disease.
[18524957] J Endocrinol 198(3): 439-50 (2008)

From fruitflies to mammals: mechanisms of signalling via the Sonic hedgehog pathway in lung development.
[11667962] Respir Res 1(1): 30-5 (2000)

Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review).
[18698484] Int J Mol Med 22(3): 271-5 (2008)

Clinical aspects of disrupted Hedgehog signaling (Review).
[11562786] Int J Mol Med 8(4): 445-52 (2001)

Implications of hedgehog signaling antagonists for cancer therapy.
[18604459] Acta Biochim Biophys Sin (Shanghai) 40(7): 670-80 (2008)

The adventures of sonic hedgehog in development and repair. IV. Sonic hedgehog processing, secretion, and function in the stomach.
[18308861] Am J Physiol Gastrointest Liver Physiol 294(5): G1105-8 (2008)

The adventures of sonic hedgehog in development and repair. II. Sonic hedgehog and liver development, inflammation, and cancer.
[18218671] Am J Physiol Gastrointest Liver Physiol 294(3): G595-8 (2008)

The adventures of Sonic Hedgehog in development and repair. I. Hedgehog signaling in gastrointestinal development and disease.
[18063705] Am J Physiol Gastrointest Liver Physiol 294(2): G363-7 (2008)

The adventures of sonic hedgehog in development and repair. III. Hedgehog processing and biological activity.
[18239057] Am J Physiol Gastrointest Liver Physiol 294(4): G844-9 (2008)

Protecting the hedgerow: p53 and hedgehog pathway interactions.
[20081367] Cell Cycle 9(3): 506-11 (2010)

Shh signaling and pancreatic cancer: implications for therapy?
[17611415] Cell Cycle 6(13): 1553-7 (2007)

Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy.
[17726373] Cell Cycle 6(20): 2458-63 (2007)

Genetic causes of human reproductive disease.
[12050198] J Clin Endocrinol Metab 87(6): 2447-54 (2002)

Cholesterol modification of Hedgehog family proteins.
[12208857] J Clin Invest 110(5): 591-6 (2002)

Primer and interviews: Diverse connections between primary cilia and Hedgehog signaling.
[20235234] Dev Dyn 239(4): 1255-62 (2010)

Targeting Hedgehog--a cancer stem cell pathway.
[20530699] Clin Cancer Res 16(12): 3130-40 (2010)

The Gli code: an information nexus regulating cell fate, stemness and cancer.
[17845852] Trends Cell Biol 17(9): 438-47 (2007)

The Hedgehog morphogen in myocardial ischemia-reperfusion injury.
[20407076] Exp Biol Med (Maywood) 235(4): 447-54 (2010)

Mechanism and evolution of cytosolic Hedgehog signal transduction.
[20530542] Development 137(13): 2079-94 (2010)

Rebuilding the coronary vasculature: hedgehog as a new candidate for pharmacologic revascularization.
[17418368] Trends Cardiovasc Med 17(3): 77-83 (2007)

Clinical implications of hedgehog signaling pathway inhibitors.
[21192841] Chin J Cancer 30(1): 13-26 (2011)

Targeting the Hedgehog pathway in cancer.
[21789137] Ther Adv Med Oncol 2(4): 237-50 (2010)

Hedgehog-Gli signaling pathway inhibitors as anticancer agents.
[19309080] J Med Chem 52(13): 3829-45 (2009)

Genetic factors in esophageal atresia, tracheo-esophageal fistula and the VACTERL association: roles for FOXF1 and the 16q24.1 FOX transcription factor gene cluster, and review of the literature.
[19822228] Eur J Med Genet 53(1): 6-13 (2010)

Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals.
[20083481] J Mol Cell Biol 2(2): 84-95 (2010)

The primary cilium as a Hedgehog signal transduction machine.
[20362092] Methods Cell Biol 94(-): 199-222 (2009)

The primary cilium at the crossroads of mammalian hedgehog signaling.
[19147008] Curr Top Dev Biol 85(-): 225-60 (2008)

Transducing the Hedgehog signal across the plasma membrane.
[18820483] Fly (Austin) 1(6): 333-6 (2007)

Hedgehog is a positive regulator of FGF signalling during embryonic tracheal cell migration.
[24651658] PLoS One 9(3):e92682 (2014)

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