LE WE PMID CA
Hedgehog1116Hedgehog

17 alpha hydroxylase 17 20 lyase

3 beta hydroxysteroid dehydrogenase2

3 beta hydroxysteroid dehydrogenase3

5 alpha Reductase

Adrenal gland (Hyperplasia congenital)

AMH

AMHR2

Androgens (Hypogonadotropic hypogonadism)

Angiogenesis

Campomelic dysplasia

Cholesterol

Cilia

CNS (Neoplasia Medulloblastoma)

DAX1 NR0B1

Denys Drash syndrome

Epithelio mesenchymal transition

Esophagus (Atresia)

Folliculogenesis

FOXC2

FOXF1

Foxl1

Frasier s syndrome

GDC0449 ttHedgehog

GLI

GLI1 protein family

Gut (Development)

Heart (Coronary heart disease BASKET)

Hedgehog

HESX1

Hypophysis (Development)

Infertility

INSL3 Insulin like 3 Relaxin like factor

Ischemia reperfusion

KAL

Kallmann s syndrome

Leptin

LHX3 Lim3

LHX4

MTHFSD

Neoplasia (Tumor biology and immunology)

NR5A1 SF1

P450 side chain cleavage

P53

Patched

Pituitary gland (Insufficiency Panhypopituitarism)

PROP1

Puberty (Delayed)

Receptor (Androgen)

Receptor (FSH)

Receptor (GnRH)

Receptor (LH)

Smoothened

SOX9

Spermatogenesis and spermatozoon

Sry

StAR

Stem cell (BASKET)

Stem cell (Neoplasia)

Steroid hormones (Synthesis)

Stomach (Anatomy)

Stomach (Development)

Testis (Development)

VACTERL association

Wnt beta Catenin TCF

WT1

1998  
1
Hedgehog and patched in neural development and disease.
[9883719] Neuron 21(6): 1243-57 (1998)
2010  
2
Sonic Hedgehog signaling in the mammalian brain.
[20218977] J Neurochem 113(3): 576-90 (2010)
2010  
3
Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.
[20716670] Pharmacol Rev 62(3): 497-524 (2010)
2002  
4
Roughing up Smoothened: chemical modulators of hedgehog signaling.
[12437769] J Biol 1(2): 8 (2002)
2002  
5
The therapeutic potential of modulators of the Hedgehog-Gli signaling pathway.
[12437768] J Biol 1(2): 9 (2002)
2010  
6
Small-molecule modulators of the Sonic Hedgehog signaling pathway.
[20024066] Mol Biosyst 6(1): 44-54 (2010)
2006  
7
The hedgehog signaling pathway in cancer.
[17062662] Clin Cancer Res 12(20 Pt 1): 5924-8 (2006)
2005  
8
Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics.
[15958535] Cancer Res 65(12): 4975-8 (2005)
1999  
9
The hedgehog signalling pathway in tumorigenesis and development.
[10630637] Oncogene 18(55): 7844-51 (1999)
2005  
10
Hedgehog signaling pathway and gastric cancer.
[16258256] Cancer Biol Ther 4(10): 1050-4 (2005)
1999  
11
Actions of hedgehog proteins on skeletal cells.
[10634584] Crit Rev Oral Biol Med 10(4): 477-86 (1999)
2007  
12
Hedgehog signaling in development and homeostasis of the gastrointestinal tract.
[17928586] Physiol Rev 87(4): 1343-75 (2007)
2007  
13
2003  
14
Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface.
[14530294] Development 130(22): 5297-305 (2003)
2009  
15
Making a grade: Sonic Hedgehog signalling and the control of neural cell fate.
[19197245] EMBO J 28(5): 457-65 (2009)
1998  
16
Transducing Hedgehog: the story so far.
[9649421] EMBO J 17(13): 3505-11 (1998)
2008  
17
The role of kinases in the Hedgehog signalling pathway.
[18379584] EMBO Rep 9(4): 330-6 (2008)
2008  
18
Hedgehog: functions and mechanisms.
[18794343] Genes Dev 22(18): 2454-72 (2008)
2001  
19
Hedgehog signaling in animal development: paradigms and principles.
[11731473] Genes Dev 15(23): 3059-87 (2001)
2008  
20
The Hedgehog protein family.
[19040769] Genome Biol 9(11): 241 (2008)
2006  
21
New "hogs" in Hedgehog transport and signal reception.
[16678090] Cell 125(3): 435-8 (2006)
2000  
22
Transducing the hedgehog signal.
[11081624] Cell 103(3): 371-4 (2000)
2000  
23
More surprises in the Hedgehog signaling pathway.
[10660040] Cell 100(2): 185-8 (2000)
1998  
24
Hedgehog and Spitz: making a match between photoreceptor axons and their targets.
[9845360] Cell 95(5): 587-90 (1998)
1998  
25
Protein splicing of inteins and hedgehog autoproteolysis: structure, function, and evolution.
[9489693] Cell 92(1): 1-4 (1998)
1995  
26
The long and short of hedgehog signaling.
[7736584] Cell 81(3): 313-6 (1995)
1995  
27
1996  
28
Sonic hedgehog: making the gradient.
[8807822] Chem Biol 3(1): 13-6 (1996)
2007  
29
Evidence for a novel feedback loop in the Hedgehog pathway involving Smoothened and Fused.
[17658259] Curr Biol 17(15): 1326-33 (2007)
2004  
30
Hedgehog signaling: measuring ligand concentrations with receptor ratios.
[15498480] Curr Biol 14(20): R889-91 (2004)
2004  
31
Hedgehog signaling: iguana debuts as a nuclear gatekeeper.
[15324687] Curr Biol 14(16): R668-70 (2004)
1998  
32
Sonic hedgehog regulates branching morphogenesis in the mammalian lung.
[9768363] Curr Biol 8(19): 1083-6 (1998)
1995  
33
Morphogenetic signalling. Responses to hedgehog.
[7552160] Curr Biol 5(6): 580-2 (1995)
2008  
34
Hedgehog signaling in development and cancer.
[19081070] Dev Cell 15(6): 801-12 (2008)
2005  
35
Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs.
[15736317] Dev Cell 8(2): 143-51 (2005)
2005  
36
Shifted from Wnt to Hedgehog signaling pathways.
[15694333] Mol Cell 17(3): 321-2 (2005)
2000  
37
The sonic hedgehog-patched-gli pathway in human development and disease.
[11001584] Am J Hum Genet 67(5): 1047-54 (2000)
2007  
38
A general role of hedgehog in the regulation of proliferation.
[17245127] Cell Cycle 6(2): 156-9 (2007)
2005  
39
Hedgehogs as negative regulators of the cell cycle.
[16082222] Cell Cycle 4(9): 1139-40 (2005)
2006  
40
Hedgehog morphogen in cardiovascular disease.
[17075024] Circulation 114(18): 1985-91 (2006)
2003  
41
How a Hedgehog might see holoprosencephaly.
[12668593] Hum Mol Genet 12 Spec No 1(-): R15-25 (2003)
2008  
42
Hedgehog signalling in endocrine development and disease.
[18524957] J Endocrinol 198(3): 439-50 (2008)
2003  
43
2000  
44
From fruitflies to mammals: mechanisms of signalling via the Sonic hedgehog pathway in lung development.
[11667962] Respir Res 1(1): 30-5 (2000)
2008  
45
Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review).
[18698484] Int J Mol Med 22(3): 271-5 (2008)
2001  
46
Clinical aspects of disrupted Hedgehog signaling (Review).
[11562786] Int J Mol Med 8(4): 445-52 (2001)
2008  
47
Implications of hedgehog signaling antagonists for cancer therapy.
[18604459] Acta Biochim Biophys Sin (Shanghai) 40(7): 670-80 (2008)
2008  
48
The adventures of sonic hedgehog in development and repair. IV. Sonic hedgehog processing, secretion, and function in the stomach.
[18308861] Am J Physiol Gastrointest Liver Physiol 294(5): G1105-8 (2008)
2008  
49
The adventures of sonic hedgehog in development and repair. II. Sonic hedgehog and liver development, inflammation, and cancer.
[18218671] Am J Physiol Gastrointest Liver Physiol 294(3): G595-8 (2008)
2008  
50
The adventures of Sonic Hedgehog in development and repair. I. Hedgehog signaling in gastrointestinal development and disease.
[18063705] Am J Physiol Gastrointest Liver Physiol 294(2): G363-7 (2008)
2008  
51
The adventures of sonic hedgehog in development and repair. III. Hedgehog processing and biological activity.
[18239057] Am J Physiol Gastrointest Liver Physiol 294(4): G844-9 (2008)
2010  
52
Protecting the hedgerow: p53 and hedgehog pathway interactions.
[20081367] Cell Cycle 9(3): 506-11 (2010)
2007  
53
Shh signaling and pancreatic cancer: implications for therapy?
[17611415] Cell Cycle 6(13): 1553-7 (2007)
2007  
54
Non-canonical activation of GLI transcription factors: implications for targeted anti-cancer therapy.
[17726373] Cell Cycle 6(20): 2458-63 (2007)
2002  
55
Genetic causes of human reproductive disease.
[12050198] J Clin Endocrinol Metab 87(6): 2447-54 (2002)
2002  
56
Cholesterol modification of Hedgehog family proteins.
[12208857] J Clin Invest 110(5): 591-6 (2002)
2010  
57
Primer and interviews: Diverse connections between primary cilia and Hedgehog signaling.
[20235234] Dev Dyn 239(4): 1255-62 (2010)
2010  
58
Targeting Hedgehog--a cancer stem cell pathway.
[20530699] Clin Cancer Res 16(12): 3130-40 (2010)
2007  
59
The Gli code: an information nexus regulating cell fate, stemness and cancer.
[17845852] Trends Cell Biol 17(9): 438-47 (2007)
2010  
60
The Hedgehog morphogen in myocardial ischemia-reperfusion injury.
[20407076] Exp Biol Med (Maywood) 235(4): 447-54 (2010)
2010  
61
Mechanism and evolution of cytosolic Hedgehog signal transduction.
[20530542] Development 137(13): 2079-94 (2010)
2007  
62
Rebuilding the coronary vasculature: hedgehog as a new candidate for pharmacologic revascularization.
[17418368] Trends Cardiovasc Med 17(3): 77-83 (2007)
2011  
63
Clinical implications of hedgehog signaling pathway inhibitors.
[21192841] Chin J Cancer 30(1): 13-26 (2011)
2010  
64
Targeting the Hedgehog pathway in cancer.
[21789137] Ther Adv Med Oncol 2(4): 237-50 (2010)
2009  
65
Hedgehog-Gli signaling pathway inhibitors as anticancer agents.
[19309080] J Med Chem 52(13): 3829-45 (2009)
2010  
66
Genetic factors in esophageal atresia, tracheo-esophageal fistula and the VACTERL association: roles for FOXF1 and the 16q24.1 FOX transcription factor gene cluster, and review of the literature.
[19822228] Eur J Med Genet 53(1): 6-13 (2010)
2010  
67
Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals.
[20083481] J Mol Cell Biol 2(2): 84-95 (2010)
2009  
68
The primary cilium as a Hedgehog signal transduction machine.
[20362092] Methods Cell Biol 94(-): 199-222 (2009)
2008  
69
The primary cilium at the crossroads of mammalian hedgehog signaling.
[19147008] Curr Top Dev Biol 85(-): 225-60 (2008)
2007  
70
Transducing the Hedgehog signal across the plasma membrane.
[18820483] Fly (Austin) 1(6): 333-6 (2007)
PMC   
71
Hedgehog is a positive regulator of FGF signalling during embryonic tracheal cell migration.
[24651658] PLoS One 9(3):e92682 (2014)

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  • Hedgehog

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