Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve Pubget Overpricing |
lüll Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs Briscoe J; Therond PDev Cell 2005[Feb]; 8 (2): 143-51Hh signaling controls cell proliferation and differentiation in processes that range from insect segmentation and limb formation to vertebrate neural tube development and bone differentiation. Moreover, Hh signaling appears to regulate stem cell homeostasis in adult tissues, while persistent Hh pathway activity has pathological consequences in a number of cancers. Two recent meetings, a Karolinska Institute Nobel conference (August 22-24, 2004) and a joint EMBO and Juan March Institute workshop (October 25-27, 2004), provided the opportunity to take stock of the progress that has been made in understanding Hh signaling and also to remind us of the many questions that still remain unanswered.|Animals[MESH]|Cell Differentiation[MESH]|Cell Proliferation[MESH]|Drosophila Proteins/*physiology[MESH]|Drosophila/growth & development/physiology[MESH]|Hedgehog Proteins[MESH]|Humans[MESH]|Models, Biological[MESH]|Neoplasms/drug therapy/etiology/physiopathology[MESH]|Signal Transduction/*physiology[MESH]|Stem Cells/physiology[MESH]|Trans-Activators/*physiology[MESH] |