Warning: Undefined variable $zfal in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Deprecated: str_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 525
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 530
Warning: Undefined variable $sterm in C:\Inetpub\vhosts\kidney.de\httpdocs\mlpefetch.php on line 531
 
English Wikipedia
Nephropedia Template TP (
Twit Text
DeepDyve
Pubget Overpricing |  
lüll
How a Hedgehog might see holoprosencephaly Roessler E; Muenke MHum Mol Genet 2003[Apr]; 12 Spec No 1 (ä): R15-25Detailed knowledge of the Hedgehog signaling pathway is fundamental to an understanding of vertebrate development as well as several birth defects in humans. Here we review various aspects of Hedgehog synthesis, secretion, distribution and function in the context of the most common anomaly of the developing forebrain in humans, holoprosencephaly. Genetic studies in numerous model organisms are beginning to elucidate the factors that are likely candidates for the causes of early embryonic defects in humans, including holoprosencephaly.|Animals[MESH]|Cholesterol/metabolism[MESH]|Disease Models, Animal[MESH]|Gene Expression Regulation[MESH]|Hedgehog Proteins[MESH]|Holoprosencephaly/*genetics/metabolism[MESH]|Humans[MESH]|Models, Biological[MESH]|Models, Genetic[MESH]|Protein Structure, Tertiary[MESH]|Signal Transduction[MESH]|Trans-Activators/*metabolism[MESH] |
