LE WE PMID CA
alpha1 Antitrypsin and its deficiency A1AT107Alpha1 Antitrypsin und dessen Mangel A1AT

alpha1 Antitrypsin and its deficiency A1AT

Cefoperazone

Lung (CT)

Pulmonary emphysema

Serpinopathy

Vasculitis (BASKET)

1984  
1
alpha 1-Antitrypsin deficiency.
[6324384] South Med J 77(4): 479-83 (1984)
1996  
2
Systemic necrotizing vasculitides in severe alpha1-antitrypsin deficiency.
[8935481] QJM 89(8): 599-611 (1996)
2010  
3
Intravenous alpha-1 antitrypsin augmentation therapy: systematic review.
[20816015] Dan Med Bull 57(9): A4175 (2010)
2007  
4
Heterozygous alpha-I antitrypsin deficiency as a co-factor in the development of chronic liver disease: a review.
[17519511] Neth J Med 65(5): 160-6 (2007)
2007  
5
Primary care diagnosis of alpha-1 antitrypsin deficiency: issues and opportunities.
[18183837] Cleve Clin J Med 74(12): 869-74 (2007)
2009  
6
Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency.
[19707408] Biologics 3(): 193-204 (2009)
1999  
7
Cefoperazone prevents the inactivation of alpha(1)-antitrypsin by activated neutrophils.
[10471586] Antimicrob Agents Chemother 43(9): 2307-10 (1999)
2006  
8
Alpha1-antitrypsin deficiency: current perspective on research, diagnosis, and management.
[18046892] Int J Chron Obstruct Pulmon Dis 1(2): 151-60 (2006)
1999  
9
Alpha 1-antitrypsin deficiency and related liver disease.
[19864752] Saudi J Gastroenterol 5(1): 1-8 (1999)
2003  
10
American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency.
[14522813] Am J Respir Crit Care Med 168(7): 818-900 (2003)
1976  
11
Alpha 1-antitrypsin deficiency and infantile liver disease.
[1085610] Arch Dis Child 51(8): 584-8 (1976)
2006  
12
The role of autophagy in alpha-1-antitrypsin deficiency: a specific cellular response in genetic diseases associated with aggregation-prone proteins.
[16874089] Autophagy 2(4): 258-63 (2006)
2009  
13
Autophagic disposal of the aggregation-prone protein that causes liver inflammation and carcinogenesis in alpha-1-antitrypsin deficiency.
[18617899] Cell Death Differ 16(1): 39-45 (2009)
2005  
14
Mortality in individuals with severe deficiency of alpha1-antitrypsin: findings from the National Heart, Lung, and Blood Institute Registry.
[15821195] Chest 127(4): 1196-204 (2005)
2004  
15
Alpha1-antitrypsin deficiency: more than a protease imbalance?
[15136365] Chest 125(5): 1607-9 (2004)
2003  
16
Augmentation therapy with alpha1-antitrypsin: patterns of use and adverse events.
[12740257] Chest 123(5): 1425-34 (2003)
1996  
17
Pathogenesis and pathology of liver disease associated with alpha 1-antitrypsin deficiency.
[8989160] Chest 110(6 Suppl): 251S-255S (1996)
1996  
18
Alpha 1-antitrypsin deficiency. A conformational disease.
[8989158] Chest 110(6 Suppl): 243S-247S (1996)
1996  
19
A 30-year perspective on alpha 1-antitrypsin deficiency.
[8989157] Chest 110(6 Suppl): 237S-242S (1996)
2004  
20
Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.
[14694355] Eur J Hum Genet 12(3): 167-72 (2004)
2007  
21
Revisiting alpha1-antitrypsin therapy in cystic fibrosis: can it still offer promise?
[17264320] Eur Respir J 29(2): 229-30 (2007)
2005  
22
alpha1-Antitrypsin deficiency and lung disease: risk modification by occupational and environmental inhalants.
[16264055] Eur Respir J 26(5): 909-17 (2005)
1990  
23
Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy.
[2185272] J Clin Invest 85(5): 1343-52 (1990)
1986  
24
alpha 1-Antitrypsin: molecular pathology, leukocytes, and tissue damage.
[3537008] J Clin Invest 78(6): 1427-31 (1986)
2008  
25
Hereditary alpha-1-antitrypsin deficiency and its clinical consequences.
[18565211] Orphanet J Rare Dis 3(): 16 (2008)
2008  
26
Alpha-1 antitrypsin: now available, but do we need it?
[18389391] Swiss Med Wkly 138(13-14): 191-6 (2008)
2004  
27
Alpha1-antitrypsin deficiency. 7: Computed tomographic imaging in alpha1-antitrypsin deficiency.
[15516477] Thorax 59(11): 986-91 (2004)
2004  
28
alpha1-Antitrypsin deficiency . 6: new and emerging treatments for alpha1-antitrypsin deficiency.
[15454659] Thorax 59(10): 904-9 (2004)
2004  
29
alpha1-Antitrypsin deficiency . 5: intravenous augmentation therapy: current understanding.
[15282394] Thorax 59(8): 708-12 (2004)
2004  
30
Alpha1-antitrypsin deficiency. 4: Molecular pathophysiology.
[15170041] Thorax 59(6): 529-35 (2004)
2004  
31
Alpha 1-antitrypsin deficiency. 3: Clinical manifestations and natural history.
[15115878] Thorax 59(5): 441-5 (2004)
2004  
32
Alpha1-antitrypsin deficiency. 2: genetic aspects of alpha(1)-antitrypsin deficiency: phenotypes and genetic modifiers of emphysema risk.
[14985567] Thorax 59(3): 259-64 (2004)
1987  
33
Association of alpha 1-antitrypsin deficiency with lung and liver diseases.
[3321708] West J Med 147(1): 48-53 (1987)
2007  
34
Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: a meeting review.
[17464974] Hepatology 45(5): 1313-23 (2007)
1996  
35
Molecular pathogenesis of liver disease in alpha1-antitrypsin deficiency.
[8938188] Hepatology 24(6): 1504-16 (1996)
2003  
36
Key current clinical issues in alpha-1 antitrypsin deficiency.
[14651762] Respir Care 48(12): 1216-21; discussion 1221-4 (2003)
2003  
37
Alpha-1 antitrypsin deficiency: an under-recognized but important issue for respiratory therapists.
[14585113] Respir Care 48(11): 1022-4 (2003)
2009  
38
Clinical characteristics of subjects with symptoms of alpha1-antitrypsin deficiency older than 60 years.
[19017884] Chest 135(3): 600-8 (2009)
2009  
39
Alpha1-antitrypsin deficiency: lessons from longevity.
[19265080] Chest 135(3): 591-2 (2009)
2008  
40
Screening and familial testing of patients for alpha 1-antitrypsin deficiency.
[18398118] Chest 133(4): 981-8 (2008)
2010  
41
Intracellular processing of alpha1-antitrypsin.
[21030516] Proc Am Thorac Soc 7(6): 376-80 (2010)
2010  
42
Lung disease associated with alpha1-antitrypsin deficiency.
[21030517] Proc Am Thorac Soc 7(6): 381-6 (2010)
2004  
43
Alpha 1-antitrypsin: more than just deficiency.
[15115856] Thorax 59(5): 363-4 (2004)
2006  
44
Validation of computed tomographic lung densitometry for monitoring emphysema in alpha1-antitrypsin deficiency.
[16537666] Thorax 61(6): 485-90 (2006)
2006  
45
The selective advantage of alpha1-antitrypsin deficiency.
[16439713] Am J Respir Crit Care Med 173(10): 1072-7 (2006)
2004  
46
Alpha-1 antitrypsin deficiency with severe pulmonary emphysema.
[15098605] Intern Med 43(3): 223-6 (2004)
2009  
47
Mechanisms of emphysema in alpha1-antitrypsin deficiency: molecular and cellular insights.
[19648523] Eur Respir J 34(2): 475-88 (2009)
2003  
48
Alpha-1 antitrypsin deficiency is not a rare disease but a disease that is rarely diagnosed.
[14654440] Environ Health Perspect 111(16): 1851-4 (2003)
2011  
49
Why has it been so difficult to prove the efficacy of alpha-1-antitrypsin replacement therapy? Insights from the study of disease pathogenesis.
[21966212] Drug Des Devel Ther 5(-): 391-405 (2011)
2008  
50
Polymers and inflammation: disease mechanisms of the serpinopathies.
[18591408] J Exp Med 205(7): 1529-34 (2008)
PMC   
51
Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice.
[24355919] J Clin Invest 124(1):251-61 (2014)
PMC   
52
Novel treatment strategies for liver disease due to alpha1-antitrypsin deficiency.
[22686209] Clin Transl Sci 5(3):289-94 (2012)
PMC   
53
Differences in adjustment between individuals with alpha-1 antitrypsin deficiency (AATD)-associated COPD and non-AATD COPD.
[23547634] COPD 10(2):226-34 (2013)

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