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alpha1 Antitrypsin and its deficiency A1AT
LE WE PMID CA
alpha1 Antitrypsin and its deficiency A1AT107Alpha1 Antitrypsin und dessen Mangel A1AT

alpha1 Antitrypsin and its deficiency A1AT

Cefoperazone

Lung (CT)

Pulmonary emphysema

Serpinopathy

Vasculitis (BASKET)

1984  
1
alpha 1-Antitrypsin deficiency.
[6324384] South Med J 77(4): 479-83 (1984)
1996  
2
Systemic necrotizing vasculitides in severe alpha1-antitrypsin deficiency.
[8935481] QJM 89(8): 599-611 (1996)
2010  
3
Intravenous alpha-1 antitrypsin augmentation therapy: systematic review.
[20816015] Dan Med Bull 57(9): A4175 (2010)
2007  
4
Heterozygous alpha-I antitrypsin deficiency as a co-factor in the development of chronic liver disease: a review.
[17519511] Neth J Med 65(5): 160-6 (2007)
2007  
5
Primary care diagnosis of alpha-1 antitrypsin deficiency: issues and opportunities.
[18183837] Cleve Clin J Med 74(12): 869-74 (2007)
2009  
6
Safety and efficacy of alpha-1-antitrypsin augmentation therapy in the treatment of patients with alpha-1-antitrypsin deficiency.
[19707408] Biologics 3(): 193-204 (2009)
1999  
7
Cefoperazone prevents the inactivation of alpha(1)-antitrypsin by activated neutrophils.
[10471586] Antimicrob Agents Chemother 43(9): 2307-10 (1999)
2006  
8
Alpha1-antitrypsin deficiency: current perspective on research, diagnosis, and management.
[18046892] Int J Chron Obstruct Pulmon Dis 1(2): 151-60 (2006)
1999  
9
Alpha 1-antitrypsin deficiency and related liver disease.
[19864752] Saudi J Gastroenterol 5(1): 1-8 (1999)
2003  
10
American Thoracic Society/European Respiratory Society statement: standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiency.
[14522813] Am J Respir Crit Care Med 168(7): 818-900 (2003)
1976  
11
Alpha 1-antitrypsin deficiency and infantile liver disease.
[1085610] Arch Dis Child 51(8): 584-8 (1976)
2006  
12
The role of autophagy in alpha-1-antitrypsin deficiency: a specific cellular response in genetic diseases associated with aggregation-prone proteins.
[16874089] Autophagy 2(4): 258-63 (2006)
2009  
13
Autophagic disposal of the aggregation-prone protein that causes liver inflammation and carcinogenesis in alpha-1-antitrypsin deficiency.
[18617899] Cell Death Differ 16(1): 39-45 (2009)
2005  
14
Mortality in individuals with severe deficiency of alpha1-antitrypsin: findings from the National Heart, Lung, and Blood Institute Registry.
[15821195] Chest 127(4): 1196-204 (2005)
2004  
15
Alpha1-antitrypsin deficiency: more than a protease imbalance?
[15136365] Chest 125(5): 1607-9 (2004)
2003  
16
Augmentation therapy with alpha1-antitrypsin: patterns of use and adverse events.
[12740257] Chest 123(5): 1425-34 (2003)
1996  
17
Pathogenesis and pathology of liver disease associated with alpha 1-antitrypsin deficiency.
[8989160] Chest 110(6 Suppl): 251S-255S (1996)
1996  
18
Alpha 1-antitrypsin deficiency. A conformational disease.
[8989158] Chest 110(6 Suppl): 243S-247S (1996)
1996  
19
A 30-year perspective on alpha 1-antitrypsin deficiency.
[8989157] Chest 110(6 Suppl): 237S-242S (1996)
2004  
20
Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.
[14694355] Eur J Hum Genet 12(3): 167-72 (2004)
2007  
21
Revisiting alpha1-antitrypsin therapy in cystic fibrosis: can it still offer promise?
[17264320] Eur Respir J 29(2): 229-30 (2007)
2005  
22
alpha1-Antitrypsin deficiency and lung disease: risk modification by occupational and environmental inhalants.
[16264055] Eur Respir J 26(5): 909-17 (2005)
1990  
23
Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy.
[2185272] J Clin Invest 85(5): 1343-52 (1990)
1986  
24
alpha 1-Antitrypsin: molecular pathology, leukocytes, and tissue damage.
[3537008] J Clin Invest 78(6): 1427-31 (1986)
2008  
25
Hereditary alpha-1-antitrypsin deficiency and its clinical consequences.
[18565211] Orphanet J Rare Dis 3(): 16 (2008)
2008  
26
Alpha-1 antitrypsin: now available, but do we need it?
[18389391] Swiss Med Wkly 138(13-14): 191-6 (2008)
2004  
27
Alpha1-antitrypsin deficiency. 7: Computed tomographic imaging in alpha1-antitrypsin deficiency.
[15516477] Thorax 59(11): 986-91 (2004)
2004  
28
alpha1-Antitrypsin deficiency . 6: new and emerging treatments for alpha1-antitrypsin deficiency.
[15454659] Thorax 59(10): 904-9 (2004)
2004  
29
alpha1-Antitrypsin deficiency . 5: intravenous augmentation therapy: current understanding.
[15282394] Thorax 59(8): 708-12 (2004)
2004  
30
Alpha1-antitrypsin deficiency. 4: Molecular pathophysiology.
[15170041] Thorax 59(6): 529-35 (2004)
2004  
31
Alpha 1-antitrypsin deficiency. 3: Clinical manifestations and natural history.
[15115878] Thorax 59(5): 441-5 (2004)
2004  
32
Alpha1-antitrypsin deficiency. 2: genetic aspects of alpha(1)-antitrypsin deficiency: phenotypes and genetic modifiers of emphysema risk.
[14985567] Thorax 59(3): 259-64 (2004)
1987  
33
Association of alpha 1-antitrypsin deficiency with lung and liver diseases.
[3321708] West J Med 147(1): 48-53 (1987)
2007  
34
Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: a meeting review.
[17464974] Hepatology 45(5): 1313-23 (2007)
1996  
35
Molecular pathogenesis of liver disease in alpha1-antitrypsin deficiency.
[8938188] Hepatology 24(6): 1504-16 (1996)
2003  
36
Key current clinical issues in alpha-1 antitrypsin deficiency.
[14651762] Respir Care 48(12): 1216-21; discussion 1221-4 (2003)
2003  
37
Alpha-1 antitrypsin deficiency: an under-recognized but important issue for respiratory therapists.
[14585113] Respir Care 48(11): 1022-4 (2003)
2009  
38
Clinical characteristics of subjects with symptoms of alpha1-antitrypsin deficiency older than 60 years.
[19017884] Chest 135(3): 600-8 (2009)
2009  
39
Alpha1-antitrypsin deficiency: lessons from longevity.
[19265080] Chest 135(3): 591-2 (2009)
2008  
40
Screening and familial testing of patients for alpha 1-antitrypsin deficiency.
[18398118] Chest 133(4): 981-8 (2008)
2010  
41
Intracellular processing of alpha1-antitrypsin.
[21030516] Proc Am Thorac Soc 7(6): 376-80 (2010)
2010  
42
Lung disease associated with alpha1-antitrypsin deficiency.
[21030517] Proc Am Thorac Soc 7(6): 381-6 (2010)
2004  
43
Alpha 1-antitrypsin: more than just deficiency.
[15115856] Thorax 59(5): 363-4 (2004)
2006  
44
Validation of computed tomographic lung densitometry for monitoring emphysema in alpha1-antitrypsin deficiency.
[16537666] Thorax 61(6): 485-90 (2006)
2006  
45
The selective advantage of alpha1-antitrypsin deficiency.
[16439713] Am J Respir Crit Care Med 173(10): 1072-7 (2006)
2004  
46
Alpha-1 antitrypsin deficiency with severe pulmonary emphysema.
[15098605] Intern Med 43(3): 223-6 (2004)
2009  
47
Mechanisms of emphysema in alpha1-antitrypsin deficiency: molecular and cellular insights.
[19648523] Eur Respir J 34(2): 475-88 (2009)
2003  
48
Alpha-1 antitrypsin deficiency is not a rare disease but a disease that is rarely diagnosed.
[14654440] Environ Health Perspect 111(16): 1851-4 (2003)
2011  
49
Why has it been so difficult to prove the efficacy of alpha-1-antitrypsin replacement therapy? Insights from the study of disease pathogenesis.
[21966212] Drug Des Devel Ther 5(-): 391-405 (2011)
2008  
50
Polymers and inflammation: disease mechanisms of the serpinopathies.
[18591408] J Exp Med 205(7): 1529-34 (2008)
PMC   
51
Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice.
[24355919] J Clin Invest 124(1):251-61 (2014)
PMC   
52
Novel treatment strategies for liver disease due to alpha1-antitrypsin deficiency.
[22686209] Clin Transl Sci 5(3):289-94 (2012)
PMC   
53
Differences in adjustment between individuals with alpha-1 antitrypsin deficiency (AATD)-associated COPD and non-AATD COPD.
[23547634] COPD 10(2):226-34 (2013)

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