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PAR
LE WE PMID CA
PAR2114PAR

Blood vessels (Physiology)

Cell polarity

Crumbs protein complex

Neoplasia (Tumor biology and immunology)

PAR

Prostacyclin

RWJ58259

Scribble

Thrombin

2003  
1
RWJ-58259: a selective antagonist of protease activated receptor-1.
[14647534] Cardiovasc Drug Rev 21(4): 313-26 (2003)
2008  
2
Gastrointestinal roles for proteinase-activated receptors in health and disease.
[17994114] Br J Pharmacol 153 Suppl 1(-): S230-40 (2008)
2004  
3
Proteinase-activated receptor pharmacology: trickier and trickier.
[15381632] Br J Pharmacol 143(4): 441 (2004)
2004  
4
Modulation of visceral pain and inflammation by protease-activated receptors.
[15051630] Br J Pharmacol 141(8): 1264-74 (2004)
2002  
5
Protease activated receptor 2 and the cardiovascular system.
[11786474] Br J Pharmacol 135(1): 14-20 (2002)
2003  
6
Protease-activated receptors: new concepts in regulation of G protein-coupled receptor signaling and trafficking.
[12966163] J Pharmacol Exp Ther 307(2): 437-42 (2003)
2002  
7
International Union of Pharmacology. XXVIII. Proteinase-activated receptors.
[12037136] Pharmacol Rev 54(2): 203-17 (2002)
2001  
8
Proteinase-activated receptors.
[11356985] Pharmacol Rev 53(2): 245-82 (2001)
2000  
9
Protease-activated receptor (PAR), a novel family of G protein-coupled seven trans-membrane domain receptors: activation mechanisms and physiological roles.
[10887946] Jpn J Pharmacol 82(3): 171-4 (2000)
2008  
10
Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity.
[18347074] J Leukoc Biol 83(6): 1309-22 (2008)
2000  
11
Review article: proteinase-activated receptors - novel signals for gastrointestinal pathophysiology.
[10735917] Aliment Pharmacol Ther 14(3): 257-66 (2000)
2001  
12
Protease activated receptors: theme and variations.
[11313904] Oncogene 20(13): 1570-81 (2001)
2005  
13
Protease-activated receptors in hemostasis, thrombosis and vascular biology.
[16102047] J Thromb Haemost 3(8): 1800-14 (2005)
2007  
14
The roles of proteinase-activated receptors in the vascular physiology and pathophysiology.
[17095716] Arterioscler Thromb Vasc Biol 27(1): 27-36 (2007)
2005  
15
Clinical relevance of proteinase activated receptors (pars) in the gut.
[15888798] Gut 54(6): 867-74 (2005)
2005  
16
Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response.
[15689571] Endocr Rev 26(1): 1-43 (2005)
2004  
17
Protease-activated receptors: contribution to physiology and disease.
[15044683] Physiol Rev 84(2): 579-621 (2004)
2007  
18
Protease-activated receptor signalling, endocytic sorting and dysregulation in cancer.
[17344429] J Cell Sci 120(Pt 6): 921-8 (2007)
2006  
19
Flow perturbation is linked to endothelial par signaling.
[16627820] Arterioscler Thromb Vasc Biol 26(5): 962-4 (2006)
2005  
20
Physiology and pathophysiology of proteinase-activated receptors (PARs): regulation of the expression of PARs.
[15655296] J Pharmacol Sci 97(1): 31-7 (2005)
2005  
21
Physiology and pathophysiology of proteinase-activated receptors (PARs): PARs in the respiratory system: cellular signaling and physiological/pathological roles.
[15655298] J Pharmacol Sci 97(1): 20-4 (2005)
2010  
22
Signal transduction by protease-activated receptors.
[20423334] Br J Pharmacol 160(2): 191-203 (2010)
2008  
23
Proteinases and signalling: pathophysiological and therapeutic implications via PARs and more.
[18059329] Br J Pharmacol 153 Suppl 1(-): S263-82 (2008)
2009  
24
Protease-activated receptors and prostaglandins in inflammatory lung disease.
[19845685] Br J Pharmacol 158(4): 1017-33 (2009)
2009  
25
Remodeling epithelial cell organization: transitions between front-rear and apical-basal polarity.
[20066074] Cold Spring Harb Perspect Biol 1(1): a000513 (2009)
2002  
26
Thrombin regulation of cell function through protease-activated receptors: implications for therapeutic intervention.
[11841340] Biochemistry (Mosc) 67(1): 56-64 (2002)
2002  
27
Receptors of the PAR family as a link between blood coagulation and inflammation.
[11841341] Biochemistry (Mosc) 67(1): 65-74 (2002)
2008  
28
Regulation of endothelial prostacyclin synthesis by protease-activated receptors: mechanisms and significance.
[18276992] Pharmacol Rep 60(1): 109-18 (2008)
2009  
29
Proteases display biased agonism at protease-activated receptors: location matters!
[19401541] Mol Interv 9(2): 87-96 (2009)
2011  
30
Elaborating polarity: PAR proteins and the cytoskeleton.
[21303844] Development 138(5): 799-809 (2011)
2005  
31
The cardiovascular actions of protease-activated receptors.
[15371558] Mol Pharmacol 67(1): 2-11 (2005)
2003  
32
Role of protease-activated receptors in the vascular system.
[14566084] J Atheroscler Thromb 10(4): 211-25 (2003)
2008  
33
Par complex in cancer: a regulator of normal cell polarity joins the dark side.
[19029931] Oncogene 27(55): 6878-87 (2008)
2010  
34
Protein targets of inflammatory serine proteases and cardiovascular disease.
[20804552] J Inflamm (Lond) 7(-): 45 (2010)

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