LE WE PMID CA
Osmosensor4635Osmosensor

ADH AVP Vasopressin

AQP5

Arterial hypertension (BASKET)

ATP

Autonomous nervous system (Afferents visceral)

Biliary system (Cholangiocyte)

Calcium (Physiology renal)

Cell volume

Cilia

Claudin4

CNS (Circumventricular organs)

Cytochrome P450 epoxygenase

Epoxyeicosatrienoic acid EET

Hypomagnesemia with hypercalciuria familiar

Ion channel (Potassium)

Ion channel (TRP Family)

Kidney (Anatomy)

Kidney (FSGS)

Kidney (Intercalated cell)

Kidney (Malformation)

Kidney (Polycystic kidney disease)

Kidney (Principal cells)

Kidney (Tubulus ascending thin limb)

Kidney (Tubulus CCD)

Kidney (Tubulus CNT)

Kidney (Tubulus Distal Convoluted)

Kidney (Tubulus IMCD)

Kidney (Tubulus TALH)

Mechanotransduction

Merkel cells

MUPP1

Nucleus supraopticus

Nup88

Organum vasculosum laminae terminalis

Osmolytes

Osmopressor response

Osmosensor

Pain (Neurophysiology)

Phospholipase A2

Signal transduction Urinary flow

Sympathetic nervous system

Tight junction

TRPC6

TRPM3

TRPM6

TRPP2

TRPV1

TRPV4

TRPV5

Water (Neurophysiology)

Water (Physiology renal)

1999  
1
Osmosensing by bacteria: signals and membrane-based sensors.
[10066837] Microbiol Mol Biol Rev 63(1): 230-62 (1999)
1989  
2
Physiological and genetic responses of bacteria to osmotic stress.
[2651863] Microbiol Rev 53(1): 121-47 (1989)
2010  
3
Hyperosmotic activation of CNS sympathetic drive: implications for cardiovascular disease.
[20603334] J Physiol 588(Pt 18): 3375-84 (2010)
2010  
4
Receptor regulation of osmolyte homeostasis in neural cells.
[20498228] J Physiol 588(Pt 18): 3355-64 (2010)
2007  
5
Role of TRPV ion channels in sensory transduction of osmotic stimuli in mammals.
[17350992] Exp Physiol 92(3): 507-12 (2007)
2008  
6
IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid.
[18378772] J Cell Biol 181(1): 143-55 (2008)
2007  
7
2007  
8
TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades
[21204498] (): (2007)
2003  
9
Impaired osmotic sensation in mice lacking TRPV4.
[12777254] Am J Physiol Cell Physiol 285(1): C96-101 (2003)
2008  
10
TRPV4 mediates hypotonicity-induced ATP release by the thick ascending limb.
[18684885] Am J Physiol Renal Physiol 295(4): F1090-5 (2008)
2007  
11
Dual role of the TRPV4 channel as a sensor of flow and osmolality in renal epithelial cells.
[17699550] Am J Physiol Renal Physiol 293(5): F1699-713 (2007)
2004  
12
Renal expression of osmotically responsive cation channel TRPV4 is restricted to water-impermeant nephron segments.
[15026302] Am J Physiol Renal Physiol 287(1): F17-24 (2004)
2007  
13
Neurophysiological characterization of mammalian osmosensitive neurones.
[17350993] Exp Physiol 92(3): 499-505 (2007)
2009  
14
Hypotonic shocks activate rat TRPV4 in yeast in the absence of polyunsaturated fatty acids.
[19174160] FEBS Lett 583(4): 754-8 (2009)
2006  
15
A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery.
[16571723] J Biol Chem 281(22): 15485-95 (2006)
2003  
16
Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress.
[12538589] J Biol Chem 278(13): 11520-7 (2003)
2012  
17
Osmoreception: perspectives on signal transduction and environmental modulation.
[22036842] Gen Comp Endocrinol 176(3): 354-60 (2012)
2007  
18
TRPV channels' role in osmotransduction and mechanotransduction.
[17217074] Handb Exp Pharmacol (179): 473-87 (2007)
2006  
19
Transient receptor potential vanilloid channels functioning in transduction of osmotic stimuli.
[17170210] J Endocrinol 191(3): 515-23 (2006)
2008  
20
IP3 sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5'-6'-epoxyeicosatrienoic acid.
[18443356] J Gen Physiol 131(5): i2 (2008)
2011  
21
Hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving TRPV1 but not TRPV4.
[21994383] J Neurosci 31(41): 14669-76 (2011)
2005  
22
TRPV4 plays an evolutionary conserved role in the transduction of osmotic and mechanical stimuli in live animals.
[15961428] J Physiol 567(Pt 1): 53-8 (2005)
2009  
23
Osmolality-induced tuning of action potentials in trigeminal ganglion neurons.
[19444958] Neurosci Lett 452(1): 79-83 (2009)
2009  
24
Changes in osmolality modulate voltage-gated sodium channels in trigeminal ganglion neurons.
[19428701] Neurosci Res 64(2): 199-207 (2009)
2008  
25
The modulation of voltage-gated potassium channels by anisotonicity in trigeminal ganglion neurons.
[18456412] Neuroscience 154(2): 482-95 (2008)
2009  
26
Rat Merkel cells are mechanoreceptors and osmoreceptors.
[19898622] PLoS One 4(11): e7759 (2009)
2007  
27
Cholangiocyte cilia express TRPV4 and detect changes in luminal tonicity inducing bicarbonate secretion.
[18024594] Proc Natl Acad Sci U S A 104(48): 19138-43 (2007)
2006  
28
Transient receptor potential vanilloid 4 regulates aquaporin-5 abundance under hypotonic conditions.
[16537379] Proc Natl Acad Sci U S A 103(12): 4747-52 (2006)
2004  
29
Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4.
[14691263] Proc Natl Acad Sci U S A 101(1): 396-401 (2004)
2003  
30
Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans.
[14581619] Proc Natl Acad Sci U S A 100 Suppl 2(): 14531-6 (2003)
2003  
31
Abnormal osmotic regulation in trpv4-/- mice.
[14581612] Proc Natl Acad Sci U S A 100(23): 13698-703 (2003)
2012  
32
Physiopathology of hereditary polyuric states: a molecular view of renal function.
[22802123] Swiss Med Wkly 142(): w13613 (2012)
2000  
33
OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity.
[11025659] Nat Cell Biol 2(10): 695-702 (2000)
2011  
34
The molecular and cellular identity of peripheral osmoreceptors.
[21262470] Neuron 69(2): 332-44 (2011)
2003  
35
Hypotonicity induces TRPV4-mediated nociception in rat.
[12895423] Neuron 39(3): 497-511 (2003)
2012  
36
Hypertonic stimulation inhibits synaptic transmission in hippocampal slices through decreasing pre-synaptic voltage-gated calcium current.
[22172932] Neurosci Lett 507(2): 106-11 (2012)
2005  
37
TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator.
[16213085] Pain 118(1-2): 70-9 (2005)
2005  
38
TRPV4 and the mammalian kidney.
[15988590] Pflugers Arch 451(1): 168-75 (2005)
2005  
39
TRPV4 as osmosensor: a transgenic approach.
[15952033] Pflugers Arch 451(1): 176-80 (2005)
2009  
40
How do kidney cells adapt to survive in hypertonic inner medulla?
[19768191] Trans Am Clin Climatol Assoc 120(-): 389-401 (2009)

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