MDM2

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MDM2

LE WE PMID CA

MDM2

6108

MDM2

ALK Anaplastic lymphoma kinase

ARF

BSI201 ttPARP1

CK1 Casein Kinase I

Crizotinib ttALK

JNJ26854165 ttMDM2

MDM2

MDM4

MDMX

Olaparib ttPARP

P53

PARP

RO5045337 ttMDM2

SCF (betaTRCP)

2009 1	Mdm2 affects genome stability independent of p53. [19244108] Cancer Res 69(5): 1697-701 (2009)
2005 2	A single nucleotide polymorphism in the MDM2 gene: from a molecular and cellular explanation to clinical effect. [15994915] Cancer Res 65(13): 5481-4 (2005)
1999 3	mdm2: a bridge over the two tumour suppressors, p53 and Rb. [10618708] Oncogene 18(53): 7681-9 (1999)
1997 4	Mdm2: keeping p53 under control. [9285554] Oncogene 15(9): 1001-10 (1997)
2002 5	p53-Mdm2--the affair that never ends. [11960904] Carcinogenesis 23(4): 541-7 (2002)
2009 6	Targeting Mdm2 and Mdmx in cancer therapy: better living through medicinal chemistry? [19147532] Mol Cancer Res 7(1): 1-11 (2009)
2004 7	MDM2 and its splice variant messenger RNAs: expression in tumors and down-regulation using antisense oligonucleotides. [14757843] Mol Cancer Res 2(1): 29-35 (2004)
2004 8	Inhibition of the p53-MDM2 interaction: targeting a protein-protein interface. [14757842] Mol Cancer Res 2(1): 20-8 (2004)
2004 9	Mdm2 in the response to radiation. [14757841] Mol Cancer Res 2(1): 9-19 (2004)
2004 10	MDM2 and prognosis. [14757840] Mol Cancer Res 2(1): 1-8 (2004)
2003 11	p53-independent functions of MDM2. [14707286] Mol Cancer Res 1(14): 1027-35 (2003)
2003 12	Posttranslational modification of MDM2. [14707285] Mol Cancer Res 1(14): 1017-26 (2003)
2003 13	Cell cycle regulatory functions of the human oncoprotein MDM2. [14707284] Mol Cancer Res 1(14): 1009-16 (2003)
2003 14	The MDM2-p53 interaction. [14707283] Mol Cancer Res 1(14): 1001-8 (2003)
2003 15	MDM2, an introduction. [14707282] Mol Cancer Res 1(14): 993-1000 (2003)
2010 16	Mdm2-mediated ubiquitylation: p53 and beyond. [19498444] Cell Death Differ 17(1): 93-102 (2010)
2010 17	The multiple levels of regulation by p53 ubiquitination. [19543236] Cell Death Differ 17(1): 86-92 (2010)
2009 18	Escape from p53-mediated tumor surveillance in neuroblastoma: switching off the p14(ARF)-MDM2-p53 axis. [19779493] Cell Death Differ 16(12): 1563-72 (2009)
2006 19	Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4. [16543935] Cell Death Differ 13(6): 927-34 (2006)
2010 20	The regulation of the p53-mediated stress response by MDM2 and MDM4. [20182601] Cold Spring Harb Perspect Biol 2(1): a000968 (2010)
2007 21	MDM2 and MDM4: p53 regulators as targets in anticancer therapy. [17499002] Int J Biochem Cell Biol 39(7-8): 1476-82 (2007)
2010 22	The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor. [20679392] Genes Dev 24(15): 1580-9 (2010)
2010 23	Novel insights into the molecular mechanisms governing Mdm2 ubiquitination and destruction. [21317463] Oncotarget 1(7): 685-90 (2010)
2010 24	The p53 orchestra: Mdm2 and Mdmx set the tone. [20172729] Trends Cell Biol 20(5): 299-309 (2010)
2011 25	Novel targeted therapeutics: inhibitors of MDM2, ALK and PARP. [21504625] J Hematol Oncol 4(-): 16 (2011)
2009 26	Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy. [18834305] Annu Rev Pharmacol Toxicol 49(-): 223-41 (2009)

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