Kidney (Fibrosis)

Epithelial to mesenchymal transition in the progression of tubulointerstitial fibrosis.
[18067769] Chin Med J (Engl) 120(21): 1925-30 (2007)

Insights into the mechanisms of renal fibrosis: is it possible to achieve regression?
[16006588] Am J Physiol Renal Physiol 289(2): F227-34 (2005)

Slowing nephropathy progression: focus on proteinuria reduction.
[18178794] Clin J Am Soc Nephrol 3 Suppl 1(-): S3-10 (2008)

Are two better than one? Angiotensin-converting enzyme inhibitors plus angiotensin receptor blockers for reducing blood pressure and proteinuria in kidney disease.
[18178792] Clin J Am Soc Nephrol 3 Suppl 1(-): S17-23 (2008)

Progression of renal disease: renoprotective specificity of renin-angiotensin system blockade.
[17699327] Clin J Am Soc Nephrol 1(5): 1054-65 (2006)

Mechanisms of tubulointerstitial injury in the kidney: final common pathways to end-stage renal failure.
[14964574] Intern Med 43(1): 9-17 (2004)

Role of mast cells in progressive renal diseases.
[18776124] J Am Soc Nephrol 19(12): 2254-61 (2008)

Renin-angiotensin-aldosterone system and progression of renal disease.
[17035613] J Am Soc Nephrol 17(11): 2985-91 (2006)

How does proteinuria cause progressive renal damage?
[17035611] J Am Soc Nephrol 17(11): 2974-84 (2006)

Renal fibroblasts and myofibroblasts in chronic kidney disease.
[17035610] J Am Soc Nephrol 17(11): 2992-8 (2006)

Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure.
[16291837] J Am Soc Nephrol 17(1): 17-25 (2006)

Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention.
[14694152] J Am Soc Nephrol 15(1): 1-12 (2004)

Chronic progression of tubulointerstitial damage in proteinuric renal disease is mediated by complement activation: a therapeutic role for complement inhibitors?
[12819326] J Am Soc Nephrol 14(7 Suppl 2): S186-91 (2003)

Molecular insights into renal interstitial fibrosis.
[8989727] J Am Soc Nephrol 7(12): 2495-508 (1996)

Experimental insights into the tubulointerstitial disease accompanying primary glomerular lesions.
[7893992] J Am Soc Nephrol 5(6): 1273-87 (1994)

The role of interstitial cells in the progression of renal diseases.
[1600137] J Am Soc Nephrol 2(10 Suppl): S198-205 (1992)

Mechanisms of progression and regression of renal lesions of chronic nephropathies and diabetes.
[16453013] J Clin Invest 116(2): 288-96 (2006)

BMP-7 and the proximal tubule.
[11786119] Kidney Int 61(1): 351-2 (2002)

The tubulointerstitium in progressive diabetic kidney disease: more than an aftermath of glomerular injury?
[10571771] Kidney Int 56(5): 1627-37 (1999)

The tubulointerstitium in progressive renal disease.
[9734628] Kidney Int 54(3): 992-4 (1998)

Treatment targets in renal fibrosis.
[17890247] Nephrol Dial Transplant 22(12): 3391-407 (2007)

The importance of tubulointerstitial damage in progressive renal disease.
[11144000] Nephrol Dial Transplant 15 Suppl 6(-): 76-7 (2000)

Tubulointerstitial damage leads to atubular glomeruli: significance and possible role in progression.
[11143999] Nephrol Dial Transplant 15 Suppl 6(-): 74-5 (2000)

Morphometry of interstitial fibrosis.
[11143998] Nephrol Dial Transplant 15 Suppl 6(-): 72-3 (2000)

Apoptosis in tubulointerstitial renal disease.
[11143992] Nephrol Dial Transplant 15 Suppl 6(-): 55-7 (2000)

Tubulo-interstitial damage in glomerular diseases: its role in the progression of the renal damage.
[9507504] Nephrol Dial Transplant 13 Suppl 1(-): 80-5 (1998)

Understanding the nature of renal disease progression.
[8995712] Kidney Int 51(1): 2-15 (1997)

Loss of glomerular function and tubulointerstitial fibrosis: cause or effect?
[8164418] Kidney Int 45(2): 345-51 (1994)

Mechanisms of tubulointerstitial fibrosis.
[2062038] Kidney Int 39(3): 550-6 (1991)

The renal tubulointerstitium in diabetes mellitus.
[2062033] Kidney Int 39(3): 464-75 (1991)

Progression of chronic renal failure in man.
[2189033] Kidney Int 37(5): 1195-210 (1990)

Preventing the progression of human renal disease: have rational therapeutic principles emerged?
[3280852] Kidney Int 33(1): 116-28 (1988)

TGF-beta signaling in renal disease.
[12239251] J Am Soc Nephrol 13(10): 2600-10 (2002)

New insights into epithelial-mesenchymal transition in kidney fibrosis.
[20019167] J Am Soc Nephrol 21(2): 212-22 (2010)

Are 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors renoprotective?
[15938026] J Am Soc Nephrol 16 Suppl 1(-): S11-7 (2005)

Capillary rarefaction, hypoxia, VEGF and angiogenesis in chronic renal disease.
[21330358] Nephrol Dial Transplant 26(4): 1132-7 (2011)

Molecular mechanisms and therapeutic strategies of chronic renal injury: physiological role of angiotensin II-induced oxidative stress in renal medulla.
[16404134] J Pharmacol Sci 100(1): 2-8 (2006)

Molecular mechanisms and therapeutic strategies of chronic renal injury: renoprotective effects of aldosterone blockade.
[16397374] J Pharmacol Sci 100(1): 9-16 (2006)

Pathophysiological roles of aldosterone and mineralocorticoid receptor in the kidney.
[21186336] J Pharmacol Sci 115(1): 1-7 (2011)

Possible underlying mechanisms responsible for aldosterone and mineralocorticoid receptor-dependent renal injury.
[19057124] J Pharmacol Sci 108(4): 399-405 (2008)

Drug discovery for overcoming chronic kidney disease (CKD): prolyl-hydroxylase inhibitors to activate hypoxia-inducible factor (HIF) as a novel therapeutic approach in CKD.
[19151537] J Pharmacol Sci 109(1): 24-31 (2009)

Replicative senescence in kidney aging, renal disease, and renal transplantation.
[21276412] Discov Med 11(56): 65-75 (2011)

Diabetic nephropathy -- a multifaceted target of new therapies.
[21122472] Discov Med 10(54): 406-15 (2010)

Macrophage diversity in renal injury and repair.
[18982158] J Clin Invest 118(11): 3522-30 (2008)

The role of proximal tubular cells in interstitial fibrosis: understanding TGF-beta1.
[17477023] Chang Gung Med J 30(1): 2-6 (2007)

Oxidative stress as a common pathway to chronic tubulointerstitial injury in kidney allografts.
[17459952] Am J Physiol Renal Physiol 293(2): F445-55 (2007)

Renal tubulointerstitial fibrosis: common but never simple.
[19144691] Am J Physiol Renal Physiol 296(6): F1239-44 (2009)

Modulation of renal inflammation: therapeutic strategies.
[18087117] Saudi J Kidney Dis Transpl 19(1): 1-19 (2008)

Renal fibrosis, origin and possible interventions: a time for action.
[16903618] Saudi J Kidney Dis Transpl 17(2): 137-48 (2006)

Intratubular hydrodynamic forces influence tubulointerstitial fibrosis in the kidney.
[19851105] Curr Opin Nephrol Hypertens 19(1): 65-71 (2010)

Angiogenesis in the kidney: a new therapeutic target?
[19430335] Curr Opin Nephrol Hypertens 18(2): 160-5 (2009)

Cyclosporine triggers endoplasmic reticulum stress in endothelial cells: a role for endothelial phenotypic changes and death.
[18987109] Am J Physiol Renal Physiol 296(1): F160-9 (2009)

Protective effect of TRPV1 against renal fibrosis via inhibition of TGF-beta/Smad signaling in DOCA-salt hypertension.
[21792478] Mol Med 17(11-12): 1204-12 (2011)

Connective tissue growth factor-(CTGF, CCN2)--a marker, mediator and therapeutic target for renal fibrosis.
[19955828] Nephron Exp Nephrol 114(3): e83-92 (2010)

Macrophage phenotype and renal fibrosis in obstructive nephropathy.
[18724069] Nephron Exp Nephrol 110(1): e31-6 (2008)

Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease.
[20865670] Histol Histopathol 25(11): 1481-96 (2010)

Pirfenidone: an anti-fibrotic therapy for progressive kidney disease.
[20050822] Expert Opin Investig Drugs 19(2): 275-83 (2010)

Fibrogenesis in kidney transplantation: potential targets for prevention and therapy.
[19935366] Transplantation 88(10): 1149-56 (2009)

Epithelial to mesenchymal transition as a biomarker in renal fibrosis: are we ready for the bedside?
[21470408] Fibrogenesis Tissue Repair 4(-): 11 (2011)

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