LE WE PMID CA
Diabetes mellitus (Beta cell decay)11102Diabetes mellitus (Betazelle Verlust)

4 phenylbutyrate

Atherosclerosis (BASKET)

Autoimmunity

Autophagy

Bax

Calcium (Endoplasmic reticulum)

Cell stress (Redox)

Ceramide

Cholecystokinin

Deoxyhypusine synthase

Diabetes mellitus (Beta cell decay)

Diabetes mellitus (t Incretins)

DJ1

DJ2

DnaJ

DP5

eIF5A

Endoplasmic reticulum (associated degradation)

ERS UFR (Apoptosis)

ERS UFR (Diseases)

ERS UFR (Induced Mediators)

ERS UFR (Pharmacology)

ERS UFR (Toxikologie)

Fatty acids (saturated)

FoxO1

GADD153 CHOP

Hes1

HSP70

Hydrogensulfide

Hypusine

IAPP islet amyloid polypeptide

iNOS

Insulin (Biosynthesis and Regulation)

Insulin (resistance)

JNK

JunB

Lipotoxicity

Liraglutide

Macelignan

MCL1

MSI1

Msi2

Musashi

Neurodegeneration

Nitric oxide NO

NOD mouse

NR1C1 PPAR alpha

Obesity (BASKET)

Palmitate

POKO mouse

Protein kinase B Akt

Receptor (PPAR gamma)

Sec61alpha1

SERCA2b

SERCA3

Ubiquitin

UCH L1

Wfs1 Wolframin

Wolfram s syndrome DIDMOAD

2008  
1
Mediators and mechanisms of pancreatic beta-cell death in type 1 diabetes.
[18438526] Arq Bras Endocrinol Metabol 52(2): 156-65 (2008)
2006  
2
Nitric oxide and endoplasmic reticulum stress.
[16645155] Arterioscler Thromb Vasc Biol 26(7): 1439-46 (2006)
2009  
3
Macroautophagy in homeostasis of pancreatic beta-cell.
[19066457] Autophagy 5(2): 241-3 (2009)
2011  
4
A lipidomic screen of palmitate-treated MIN6 beta-cells links sphingolipid metabolites with endoplasmic reticulum (ER) stress and impaired protein trafficking.
[21265737] Biochem J 435(1): 267-76 (2011)
2011  
5
Hydrogen sulphide protects mouse pancreatic beta-cells from cell death induced by oxidative stress, but not by endoplasmic reticulum stress.
[21091646] Br J Pharmacol 162(5): 1171-8 (2011)
2011  
6
The central role of calcium in the effects of cytokines on beta-cell function: implications for type 1 and type 2 diabetes.
[21944825] Cell Calcium 50(6): 481-90 (2011)
2011  
7
Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling.
[21389784] Cell Cycle 10(7): 1043-9 (2011)
2011  
8
Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to beta-cell apoptosis.
[20798690] Cell Death Differ 18(2): 328-37 (2011)
2009  
9
Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis.
[19629134] Cell Death Differ 16(11): 1539-50 (2009)
2004  
10
hsp70-DnaJ chaperone pair prevents nitric oxide- and CHOP-induced apoptosis by inhibiting translocation of Bax to mitochondria.
[14752510] Cell Death Differ 11(4): 390-402 (2004)
2011  
11
Musashi expression in beta-cells coordinates insulin expression, apoptosis and proliferation in response to endoplasmic reticulum stress in diabetes.
[22113197] Cell Death Dis 2(): e232 (2011)
2011  
12
Gene-activation mechanisms in the regression of atherosclerosis, elimination of diabetes type 2, and prevention of dementia.
[21568932] Curr Mol Med 11(5): 391-400 (2011)
2012  
13
Islet beta-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model.
[22442300] Diabetes 61(4): 818-27 (2012)
2012  
14
ER stress as a trigger for beta-cell dysfunction and autoimmunity in type 1 diabetes.
[22442299] Diabetes 61(4): 780-1 (2012)
2011  
15
Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic beta-cells: interplay with cell metabolism and [Ca2+]c and role of SERCA2b and SERCA3.
[21885870] Diabetes 60(10): 2533-45 (2011)
2011  
16
Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and beta-cell dysfunction in humans.
[21270237] Diabetes 60(3): 918-24 (2011)
2011  
17
beta-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency.
[20980462] Diabetes 60(1): 227-38 (2011)
2011  
18
In vivo misfolding of proinsulin below the threshold of frank diabetes.
[21677281] Diabetes 60(8): 2092-101 (2011)
2010  
19
A point mutation in Sec61alpha1 leads to diabetes and hepatosteatosis in mice.
[19934005] Diabetes 59(2): 460-70 (2010)
2009  
20
Successful versus failed adaptation to high-fat diet-induced insulin resistance: the role of IAPP-induced beta-cell endoplasmic reticulum stress.
[19151199] Diabetes 58(4): 906-16 (2009)
2008  
21
Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes.
[18065517] Diabetes 57(3): 737-45 (2008)
2008  
22
Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.
[18174526] Diabetes 57(4): 846-59 (2008)
2007  
23
Impairment of the ubiquitin-proteasome pathway is a downstream endoplasmic reticulum stress response induced by extracellular human islet amyloid polypeptide and contributes to pancreatic beta-cell apoptosis.
[17563070] Diabetes 56(9): 2284-94 (2007)
2007  
24
High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes.
[17475933] Diabetes 56(8): 2016-27 (2007)
2005  
25
Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities.
[16306347] Diabetes 54 Suppl 2(): S97-107 (2005)
2005  
26
Mechanisms of beta-cell death in type 2 diabetes.
[16306327] Diabetes 54 Suppl 2(): S108-13 (2005)
2011  
27
The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes.
[21340625] Diabetologia 54(5): 1098-108 (2011)
2009  
28
Adaptation and failure of pancreatic beta cells in murine models with different degrees of metabolic syndrome.
[19841237] Dis Model Mech 2(11-12): 582-92 (2009)
2010  
29
Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival.
[20534724] Endocrinology 151(8): 3577-88 (2010)
2005  
30
Endoplasmic reticulum stress induces Wfs1 gene expression in pancreatic beta-cells via transcriptional activation.
[15994758] Eur J Endocrinol 153(1): 167-76 (2005)
2012  
31
Modulation of apoptosis pathways by oxidative stress and autophagy in beta cells.
[22474427] Exp Diabetes Res 2012(): 647914 (2012)
2012  
32
Endoplasmic reticulum stress and insulin biosynthesis: a review.
[22474424] Exp Diabetes Res 2012(): 509437 (2012)
2012  
33
The role of endoplasmic reticulum stress in autoimmune-mediated beta-cell destruction in type 1 diabetes.
[22454627] Exp Diabetes Res 2012(): 238980 (2012)
2012  
34
Role of autophagy in diabetes and endoplasmic reticulum stress of pancreatic beta-cells.
[22257883] Exp Mol Med 44(2): 81-8 (2012)

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  • Diabetes mellitus (Betazelle Verlust)

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