Cytochrome P450

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Cytochrome P450

LE WE PMID CA

Cytochrome P450

2983

Zytochrom P450

Cytochrome P450

Enzyme structure and chemistry

Heme

NR1I2 Pregnane X Receptor

2004 1	Inhibition of cytochrome P450 by furanocoumarins in grapefruit juice and herbal medicines. [14769198] Acta Pharmacol Sin 25(2): 129-36 (2004)
2001 2	Recent advances in P450 research. [11908754] Pharmacogenomics J 1(3): 178-86 (2001)
1998 3	Physiological and pathophysiological regulation of cytochrome P450. [9860933] Drug Metab Dispos 26(12): 1232-40 (1998)
1998 4	Structure-function of cytochromes P450 and flavin-containing monooxygenases: implications for drug metabolism. [9860932] Drug Metab Dispos 26(12): 1223-31 (1998)
1998 5	Molecular basis of P450 inhibition and activation: implications for drug development and drug therapy. [9860924] Drug Metab Dispos 26(12): 1179-84 (1998)
1998 6	The 1996 Bernard B. Brodie lecture: A journey in cytochrome P450 and drug metabolism research. [9860921] Drug Metab Dispos 26(12): 1168-73 (1998)
2007 7	Review article: The prevalence and clinical relevance of cytochrome P450 polymorphisms. [18081664] Aliment Pharmacol Ther 26 Suppl 2(-): 211-9 (2007)
1999 8	Concise review of the cytochrome P450s and their roles in toxicology. [10353305] Toxicol Sci 48(2): 151-6 (1999)
1991 9	Cytochrome P-450. Multiplicity of isoforms, substrates, and catalytic and regulatory mechanisms. [1856184] J Biol Chem 266(21): 13469-72 (1991)
1991 10	Reactions and significance of cytochrome P-450 enzymes. [2037557] J Biol Chem 266(16): 10019-22 (1991)
1990 11	The enzymes of detoxication. [2249981] J Biol Chem 265(34): 20715-8 (1990)
1993 12	Molecular evolution of P450 superfamily and P450-containing monooxygenase systems. [8405421] FEBS Lett 332(1-2): 1-8 (1993)
2008 13	Oxygen activation by cytochrome P450 monooxygenase. [18600471] Photosynth Res 98(1-3): 657-66 (2008)
2007 14	Reactivity patterns of cytochrome P450 enzymes: multifunctionality of the active species, and the two states-two oxidants conundrum. [17534529] Nat Prod Rep 24(3): 533-52 (2007)
2007 15	Variations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily. [17534532] Nat Prod Rep 24(3): 585-609 (2007)
2007 16	Sterol 14alpha-demethylase cytochrome P450 (CYP51), a P450 in all biological kingdoms. [16963187] Biochim Biophys Acta 1770(3): 467-77 (2007)
2009 17	Cooperative properties of cytochromes P450. [19555717] Pharmacol Ther 124(2): 151-67 (2009)
2005 18	Possible involvement of singlet oxygen species as multiple oxidants in p450 catalytic reactions. [15770070] Drug Metab Pharmacokinet 20(1): 1-13 (2005)
2008 19	Interplay of pregnane X receptor with other nuclear receptors on gene regulation. [18305371] Drug Metab Pharmacokinet 23(1): 14-21 (2008)
2007 20	Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development. [17544277] Bioorg Med Chem 15(15): 5047-60 (2007)
2008 21	Bis-histidine-coordinated hemes in four-helix bundles: how the geometry of the bundle controls the axial imidazole plane orientations in transmembrane cytochromes of mitochondrial complexes II and III and related proteins. [18418633] J Biol Inorg Chem 13(4): 481-98 (2008)
2010 22	On the general mechanism of selective induction of cytochrome P450 enzymes by chemicals: some theoretical considerations. [20113197] Expert Opin Drug Metab Toxicol 6(4): 483-94 (2010)
2008 23	Allosteric P450 mechanisms: multiple binding sites, multiple conformers or both? [19040328] Expert Opin Drug Metab Toxicol 4(12): 1523-35 (2008)

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