LE WE PMID CA
BRAF8055BRAF

BRAF

Cardio facio cutaneous syndrome

Colon and rectum (Neoplasia)

ERK

KRAS

MAP2K1

MAP2K2

NRAS

PI3KC3

PLX4032

Skin (Neoplasia Melanoma)

Thyroid (Neoplasia)

Thyroid (Neoplasm Papillary thyroid carcinoma)

2009  
1
Tumour cell survival signalling by the ERK1/2 pathway.
[18846109] Cell Death Differ 16(3): 368-77 (2009)
2010  
2
Selectively targeting mutant BRAF in thyroid cancer.
[20056810] J Clin Endocrinol Metab 95(1): 60-1 (2010)
2010  
3
BRAF, a target in melanoma: implications for solid tumor drug development.
[20629085] Cancer 116(21): 4902-13 (2010)
2007  
4
Clinicopathologic significance of BRAF V600E mutation in papillary carcinomas of the thyroid: a meta-analysis.
[17520704] Cancer 110(1): 38-46 (2007)
2007  
5
Targeting BRAF in thyroid cancer.
[17179987] Br J Cancer 96(1): 16-20 (2007)
2009  
6
Integrating BRAF/MEK inhibitors into combination therapy for melanoma.
[19156138] Br J Cancer 100(3): 431-5 (2009)
2007  
7
2011  
8
Potential therapeutic strategies to overcome acquired resistance to BRAF or MEK inhibitors in BRAF mutant cancers.
[21505228] Oncotarget 2(4): 336-46 (2011)
2009  
9
Spectrum of MEK1 and MEK2 gene mutations in cardio-facio-cutaneous syndrome and genotype-phenotype correlations.
[19156172] Eur J Hum Genet 17(6): 733-40 (2009)
2010  
10
Understanding melanoma signaling networks as the basis for molecular targeted therapy.
[19571822] J Invest Dermatol 130(1): 28-37 (2010)
2010  
11
Colorectal cancer: cetuximab, KRAS, BRAF, PIK3CA mutations and beyond.
[20932136] Expert Rev Gastroenterol Hepatol 4(5): 525-9 (2010)
2010  
12
Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032.
[20630094] J Transl Med 8(-): 67 (2010)
2007  
13
Mouse models for BRAF-induced cancers.
[17956344] Biochem Soc Trans 35(Pt 5): 1329-33 (2007)
2011  
14
Targeting BRAF for patients with melanoma.
[21139585] Br J Cancer 104(3): 392-8 (2011)

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