CTLA4

LE WE PMID CA

CTLA4

4990

CTLA4

Abatacept ttCTLA4Conjugate

Arthritis (juvenile idiopathic)

Asthma (BASKET)

B7RP1

CD25

CD28

CD80

CD86

CTLA4

Cyclophosphamide

ICOS

Ipilimumab ttCTLA4

NOD mouse

Regulatory T cell

Skin (Neoplasia Melanoma)

Tremelimumab ttCLTA4

Vaccine (Oncology)

2006 1	CD28/CTLA-4--CD80/CD86 and ICOS--B7RP-1 costimulatory pathway in bronchial asthma. [16364152] Allergy 61(1): 15-26 (2006)
1999 2	The role of CTLA-4 in the regulation of T cell immune responses. [10101680] Immunol Cell Biol 77(1): 1-10 (1999)
1997 3	The emerging role of CTLA-4 as an immune attenuator. [9354465] Immunity 7(4): 445-50 (1997)
2000 4	CD28, CTLA-4 and their ligands: who does what and to whom? [11012769] Immunology 101(2): 169-77 (2000)
2007 5	Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignancies. [18000991] Cancer 110(12): 2614-27 (2007)
2007 6	Cytotoxic T-lymphocyte-associated antigen-4. [17875750] Clin Cancer Res 13(18 Pt 1): 5238-42 (2007)
2008 7	Overcoming immunologic tolerance to melanoma: targeting CTLA-4 with ipilimumab (MDX-010). [19001147] Oncologist 13 Suppl 4(-): 16-25 (2008)
2008 8	Overcoming immunologic tolerance to melanoma: targeting CTLA-4 with tremelimumab (CP-675,206). [19001146] Oncologist 13 Suppl 4(-): 10-5 (2008)
2008 9	The mechanism of anti-CTLA-4 activity and the negative regulation of T-cell activation. [19001145] Oncologist 13 Suppl 4(-): 2-9 (2008)
2008 10	Immunoregulatory pathways controlling progression of autoimmunity in NOD mice. [19120317] Ann N Y Acad Sci 1150(-): 300-10 (2008)
2011 11	Adenovirus-mediated intratumoral expression of immunostimulatory proteins in combination with systemic Treg inactivation induces tumor-destructive immune responses in mouse models. [21394107] Cancer Gene Ther 18(6): 407-18 (2011)
2011 12	Abatacept in the treatment of polyarticular JIA: development, clinical utility, and place in therapy. [21340039] Drug Des Devel Ther 5(-): 61-70 (2011)

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