CD95 FAS Apo1

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CD95 FAS Apo1

LE WE PMID CA

CD95 FAS Apo1

486

CD95 FAS Apo1

17 N allylamino 17 demethoxygeldanamycin

Apoptosis

Arsenic trioxide ttROS

ATF2

c Jun

Cajal body

CAR coxsackie and adenovirus receptor

Caspase8

CD95 FAS Apo1

CD95L FASL

Ceramide synthase6

Ceramide

Cisplatin

Efferocytosis

EIF2AK3 PERK

Fenretinide

FLASH

Interferon beta

Interleukin24 MDA7

JNK

Kidney (Neoplasia RCC)

Neoplasia (Oncolytic virus)

NOK1 ttCD95L

PML nuclear bodies

Receptor (Death)

Skin (Neoplasia Melanoma)

Sorafenib

Sp100

Sphingomyelinase

TRAIL APO2

2002 1	Activation-induced cell death: the controversial role of Fas and Fas ligand in immune privilege and tumour counterattack. [11940113] Immunol Cell Biol 80(2): 131-7 (2002)
1999 2	Cell death induced by the Fas/Fas ligand pathway and its role in pathology. [10457197] Immunol Cell Biol 77(4): 312-7 (1999)
1999 3	Signalling by CD95 and TNF receptors: not only life and death. [10101685] Immunol Cell Biol 77(1): 41-6 (1999)
2009 4	The many roles of FAS receptor signaling in the immune system. [19239902] Immunity 30(2): 180-92 (2009)
1996 5	Fas-induced apoptosis, and diseases caused by its abnormality. [9077447] Genes Cells 1(10): 873-9 (1996)
1998 6	Human autoimmune lymphoproliferative syndrome, a defect in the apoptosis-inducing Fas receptor: a lesson from the mouse model. [9609991] J Hum Genet 43(1): 2-8 (1998)
1998 7	CD95 mediated T cell apoptosis and its relevance to immune deviation. [9916989] Oncogene 17(25): 3271-6 (1998)
1996 8	Looking beneath the surface: the cell death pathway of Fas/APO-1 (CD95). [8900530] Mol Med 2(1): 7-20 (1996)
1999 9	The spectrum of apoptotic defects and clinical manifestations, including systemic lupus erythematosus, in humans with CD95 (Fas/APO-1) mutations. [10513797] Arthritis Rheum 42(9): 1833-42 (1999)
2005 10	Induction of tolerance using Fas ligand: a double-edged immunomodulator. [15486063] Blood 105(4): 1396-404 (2005)
2009 11	Tyrosine phosphorylation and CD95: a FAScinating switch. [19221505] Cell Cycle 8(6): 838-42 (2009)
2007 12	FLASH meets nuclear bodies: CD95 receptor signals via a nuclear pathway. [17377497] Cell Cycle 6(7): 771-5 (2007)
2003 13	The CD95(APO-1/Fas) DISC and beyond. [12655293] Cell Death Differ 10(1): 26-35 (2003)
2008 14	microRNAs and death receptors. [18490189] Cytokine Growth Factor Rev 19(3-4): 303-11 (2008)
2011 15	Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery. [20948318] Cancer Biol Ther 10(12): 1290-305 (2011)
2005 16	Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells. [15833826] Cancer Res 65(8): 3017-24 (2005)
2008 17	Killing of human melanoma cells induced by activation of class I interferon-regulated signaling pathways via MDA-7/IL-24. [18511292] Cytokine 43(1): 34-44 (2008)
2009 18	MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism. [19417161] Mol Cancer Ther 8(5): 1280-91 (2009)
2011 19	A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels. [21119025] Mol Pharmacol 79(3): 368-80 (2011)
2010 20	Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells. [19910452] Mol Pharmacol 77(2): 298-310 (2010)
2009 21	APO-1/Fas gene: Structural and functional characteristics in systemic lupus erythematosus and other autoimmune diseases. [21088713] Indian J Hum Genet 15(3): 98-102 (2009)
2008 22	Fas expression on antigen-specific T cells has costimulatory, helper, and down-regulatory functions in vivo for cytotoxic T cell responses but not for T cell-dependent B cell responses. [18941180] J Immunol 181(9): 5912-29 (2008)
2009 23	Many checkpoints on the road to cell death: regulation of Fas-FasL interactions and Fas signaling in peripheral immune responses. [19132321] Results Probl Cell Differ 49(-): 17-47 (2009)

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