suck pdf from google scholar
unlimited free pdf from europmc19641683    free
PDF from PMC    free
html from PMC    free
suck pdf from library genesis
English Wikipedia

Nephropedia Template TP (

Twit Text


  • DeepDyve
  • Pubget Overpricing


  • lüll
  • Pathophysiological role of autoantibodies against G-protein-coupled receptors in the cardiovascular system
  • Schulze W; Kunze R; Wallukat G
  • Exp Clin Cardiol 2005[Fal]; 10 (3): 170-2
  • After more than 15 years of intensive research in the field of functional autoantibodies (AAB) directed against G-protein-coupled receptors, there is growing evidence of a causal involvement of AAB in various cardiovascular diseases such as dilated cardiomyopathy, peripartum cardiomyopathy, malignant and essential hypertension, and preeclampsia. It has been indicated that AAB against beta-1 adrenergic receptor, alpha-1 adrenergic receptor, angiotensin-II receptor AT(1) and muscarinic M(2)-receptors undergo agonist-like actions on the corresponding receptor and induce a permanent stimulation of G-protein-coupled signal cascades, which may cause Ca(2+) overload and cardiomyocyte destruction.Furthermore, the present review describes how G-protein-coupled receptor AAB are able to activate transcription factor nuclear factor-kappa B, which may regulate the expression of genes involved in immune and inflammatory responses.
  • ä





  • *{{pmid19641683}}
    *<b>[http://www.kidney.de/mlpefetch.php?search=19641683 Pathophysiological role of autoantibodies against G-protein-coupled receptors in the cardiovascular system ]</b> Exp Clin Cardiol 2005; 10(3) ; 170-2 Schulze W; Kunze R; Wallukat G

        *19641683*

    Nephropedia PMID record

    Deutsche Wikipedia - im Artikel

    Hier den unten stehenden Textblock hineinkopieren

    Exp Clin Cardiol

    170 3.10 2005