LE WE PMID CA
Irritable bowel syndrome2389Reizdarm

Alosetron

Amygdala

Asimadoline ttOpiatK

Cajal Interstitial cells of Cajal

Celiac disease

Chromogranin A

Constipation

Gabapentin

Gastroesophageal reflux disease

Inflammatory bowel diseases

Irritable bowel syndrome

Linaclotide ttGuanylatecyclaseC

Lubiprostone

Mast cells

Microbiomics

Otilonium bromide

Pregabalin

SeHCAT

Stress (Neurophysiology)

Tegaserod

TRPV1

Tryptophan hydroxylase

2001  
1
Pathophysiology and management of irritable bowel syndrome.
[11769571] Korean J Intern Med 16(3): 137-46 (2001)
2003  
2
A systematic review of alternative therapies in the irritable bowel syndrome.
[12578506] Arch Intern Med 163(3): 265-74 (2003)
2001  
3
Evidence- and consensus-based practice guidelines for the diagnosis of irritable bowel syndrome.
[11570936] Arch Intern Med 161(17): 2081-8 (2001)
2009  
4
Complementary and alternative medicine for treatment of irritable bowel syndrome.
[19221071] Can Fam Physician 55(2): 143-8 (2009)
1994  
5
Irritable bowel syndrome. Strategy for the family physician.
[8130678] Can Fam Physician 40(-): 307-10, 313-6 (1994)
2005  
6
Cognitive-behavioral treatment of irritable bowel syndrome.
[16273018] CNS Spectr 10(11): 883-90 (2005)
2004  
7
Treating irritable bowel syndrome: overview, perspective and future therapies.
[15037521] Br J Pharmacol 141(8): 1237-48 (2004)
2007  
8
Tegaserod in the treatment of irritable bowel syndrome (IBS) with constipation as the prime symptom.
[18360619] Ther Clin Risk Manag 3(1): 107-18 (2007)
2009  
9
Autonomic testing in functional gastrointestinal disorders: implications of reproducible gastrointestinal complaints during tilt table testing.
[19424509] Gastroenterol Res Pract 2009(-): 868496 (2009)
2008  
10
Review article: abdominal bloating and distension in functional gastrointestinal disorders--epidemiology and exploration of possible mechanisms.
[17931344] Aliment Pharmacol Ther 27(1): 2-10 (2008)
2007  
11
Systematic review and meta-analysis: The incidence and prognosis of post-infectious irritable bowel syndrome.
[17661757] Aliment Pharmacol Ther 26(4): 535-44 (2007)
2007  
12
Systematic review: the prevalence of suicidal behaviour in patients with chronic abdominal pain and irritable bowel syndrome.
[17593064] Aliment Pharmacol Ther 26(2): 183-93 (2007)
2007  
13
Review article: the role of antibiotics vs. conventional pharmacotherapy in treating symptoms of irritable bowel syndrome.
[17509095] Aliment Pharmacol Ther 25(11): 1271-81 (2007)
2006  
14
Review article: modulation of the brain-gut axis as a therapeutic approach in gastrointestinal disease.
[16948804] Aliment Pharmacol Ther 24(6): 919-33 (2006)
2006  
15
Systematic review: the effectiveness of hypnotherapy in the management of irritable bowel syndrome.
[16918880] Aliment Pharmacol Ther 24(5): 769-80 (2006)
2006  
16
Systematic review: the safety and tolerability of pharmacological agents for treatment of irritable bowel syndrome--a European perspective.
[16842449] Aliment Pharmacol Ther 24(2): 207-36 (2006)
2006  
17
Systematic review: the efficacy of treatments for irritable bowel syndrome--a European perspective.
[16842448] Aliment Pharmacol Ther 24(2): 183-205 (2006)
2006  
18
Review article: intestinal serotonin signalling in irritable bowel syndrome.
[16611266] Aliment Pharmacol Ther 23(8): 1067-76 (2006)
2006  
19
Systematic review: Complementary and alternative medicine in the irritable bowel syndrome.
[16441466] Aliment Pharmacol Ther 23(4): 465-71 (2006)
2005  
20
Review article: The history of hypnotherapy and its role in the irritable bowel syndrome.
[16305719] Aliment Pharmacol Ther 22(11-12): 1061-7 (2005)
2005  
21
Review article: drugs interfering with visceral sensitivity for the treatment of functional gastrointestinal disorders--the clinical evidence.
[15771750] Aliment Pharmacol Ther 21(6): 633-51 (2005)
2004  
22
Meta-analysis: The treatment of irritable bowel syndrome.
[15606387] Aliment Pharmacol Ther 20(11-12): 1253-69 (2004)
2004  
23
Review article: therapeutic roles of acupuncture in functional gastrointestinal disorders.
[15479354] Aliment Pharmacol Ther 20(8): 831-41 (2004)
2004  
24
Irritable bowel syndrome - an evidence-based approach to diagnosis.
[15191504] Aliment Pharmacol Ther 19(12): 1235-45 (2004)
2004  
25
Review article: The rationale for antidepressant therapy in functional gastrointestinal disorders.
[15113363] Aliment Pharmacol Ther 19(9): 969-79 (2004)
2004  
26
Systemic review: Natural history of irritable bowel syndrome.
[15080847] Aliment Pharmacol Ther 19(8): 861-70 (2004)
2004  
27
Systematic review: the role of different types of fibre in the treatment of irritable bowel syndrome.
[14984370] Aliment Pharmacol Ther 19(3): 245-51 (2004)
2003  
28
Clinical trial guidelines for pharmacological treatment of irritable bowel syndrome.
[12969083] Aliment Pharmacol Ther 18(6): 569-80 (2003)
2003  
29
Review article: botulinum toxin in the therapy of gastrointestinal motility disorders.
[12848622] Aliment Pharmacol Ther 18(1): 1-16 (2003)
2003  
30
Systematic review: Abdominal and pelvic surgery in patients with irritable bowel syndrome.
[12694081] Aliment Pharmacol Ther 17(8): 997-1005 (2003)
2003  
31
Review article: visceral hypersensitivity.
[12641510] Aliment Pharmacol Ther 17(5): 623-33 (2003)
2002  
32
Review article: bloating in functional bowel disorders.
[12390095] Aliment Pharmacol Ther 16(11): 1867-76 (2002)
2002  
33
Clinical perspectives, mechanisms, diagnosis and management of irritable bowel syndrome.
[12182741] Aliment Pharmacol Ther 16(8): 1407-30 (2002)
2002  
34
The treatment of irritable bowel syndrome.
[12182740] Aliment Pharmacol Ther 16(8): 1395-406 (2002)
2002  
35
Review article: the complexity of drug development for irritable bowel syndrome.
[11876686] Aliment Pharmacol Ther 16(3): 343-51 (2002)
2001  
36
Food hypersensitivity and irritable bowel syndrome.
[11284772] Aliment Pharmacol Ther 15(4): 439-49 (2001)
2001  
37
Meta-analysis of smooth muscle relaxants in the treatment of irritable bowel syndrome.
[11207510] Aliment Pharmacol Ther 15(3): 355-61 (2001)
1998  
38
Review article: colonic sensorimotor physiology in health, and its alteration in constipation and diarrhoeal disorders.
[9690718] Aliment Pharmacol Ther 12(4): 287-302 (1998)
2010  
39
Review article: new receptor targets for medical therapy in irritable bowel syndrome.
[19785622] Aliment Pharmacol Ther 31(1): 35-46 (2010)
2009  
40
Systematic review: the prevalence of idiopathic bile acid malabsorption as diagnosed by SeHCAT scanning in patients with diarrhoea-predominant irritable bowel syndrome.
[19570102] Aliment Pharmacol Ther 30(7): 707-17 (2009)
2009  
41
Review article: visceral hypersensitivity in irritable bowel syndrome: molecular mechanisms and therapeutic agents.
[19493256] Aliment Pharmacol Ther 30(5): 423-35 (2009)
2008  
42
Review article: probiotics and prebiotics in irritable bowel syndrome.
[18532993] Aliment Pharmacol Ther 28(4): 385-96 (2008)
2008  
43
Review article: molecular, pathological and therapeutic features of human enteric neuropathies.
[18410560] Aliment Pharmacol Ther 28(1): 25-42 (2008)
2008  
44
Review article: gastrointestinal sensory and motor disturbances in inflammatory bowel disease - clinical relevance and pathophysiological mechanisms.
[18221407] Aliment Pharmacol Ther 27(8): 621-37 (2008)
2004  
45
Review article: serotonin receptors and transporters -- roles in normal and abnormal gastrointestinal motility.
[15521849] Aliment Pharmacol Ther 20 Suppl 7(-): 3-14 (2004)
2004  
46
Diagnosis and therapy of irritable bowel syndrome.
[15335409] Aliment Pharmacol Ther 20 Suppl 2(-): 10-22 (2004)
2004  
47
New pathophysiological mechanisms in irritable bowel syndrome.
[15335408] Aliment Pharmacol Ther 20 Suppl 2(-): 1-9 (2004)
1997  
48
Review article: irritable bowel syndrome.
[9042970] Aliment Pharmacol Ther 11(1): 3-15 (1997)
2007  
49
In the clinic. Irritable bowel syndrome.
[17606954] Ann Intern Med 147(1): ITC7-1-ITC7-16 (2007)
2006  
50
Treatment for bacterial overgrowth in the irritable bowel syndrome.
[17043344] Ann Intern Med 145(8): 626-8 (2006)
2005  
51
Use of psychopharmacological agents for functional gastrointestinal disorders.
[16099800] Gut 54(9): 1332-41 (2005)
2000  
52
British Society of Gastroenterology guidelines for the management of the irritable bowel syndrome.
[11053260] Gut 47 Suppl 2(-): ii1-19 (2000)
1984  
53
2003  
54
Management of irritable bowel syndrome.
[12697915] Postgrad Med J 79(929): 154-8 (2003)
1997  
55
1991  
56
Current views on the aetiology and management of the irritable bowel syndrome.
[1946124] Postgrad Med J 67(791): 785-9 (1991)
2008  
57
Meta-analysis of probiotics for the treatment of irritable bowel syndrome.
[18461650] World J Gastroenterol 14(17): 2650-61 (2008)
2008  
58
Updates on treatment of irritable bowel syndrome.
[18461649] World J Gastroenterol 14(17): 2639-49 (2008)
2007  
59
Neuropathophysiology of functional gastrointestinal disorders.
[17457962] World J Gastroenterol 13(9): 1313-32 (2007)
2007  
60
Differential diagnosis between functional and organic intestinal disorders: is there a role for non-invasive tests?
[17226899] World J Gastroenterol 13(2): 219-23 (2007)
2011  
61
Management of irritable bowel syndrome (IBS) in adults: conventional and complementary/alternative approaches.
[21649455] Altern Med Rev 16(2): 134-51 (2011)
2004  
62
The causes of intestinal dysbiosis: a review.
[15253677] Altern Med Rev 9(2): 180-97 (2004)
2006  
63
How stress induces intestinal hypersensitivity.
[16400003] Am J Pathol 168(1): 3-5 (2006)
2008  
64
Diagnosis and management of irritable bowel syndrome in adults in primary care: summary of NICE guidance.
[18325967] BMJ 336(7643): 556-8 (2008)
2006  
65
Functional findings in irritable bowel syndrome.
[16718806] World J Gastroenterol 12(18): 2830-8 (2006)
2011  
66
Need for a comprehensive medical approach to the neuro-immuno-gastroenterology of irritable bowel syndrome.
[21734786] World J Gastroenterol 17(23): 2791-800 (2011)
2008  
67
Postinfectious irritable bowel syndrome.
[18205536] Clin Infect Dis 46(4): 594-9 (2008)
2004  
68
Role of serotonin in the pathophysiology of the irritable bowel syndrome.
[15100164] Br J Pharmacol 141(8): 1285-93 (2004)
2011  
69
Interstitial cells of Cajal: a novel hypothesis for the pathophysiology of irritable bowel syndrome.
[21647464] Can J Gastroenterol 25(5): 277-9 (2011)
2011  
70
Neuroimmune mechanisms in functional bowel disorders.
[21411840] Neth J Med 69(2): 55-61 (2011)
2006  
71
Histopathological alterations in irritable bowel syndrome.
[17013373] Mod Pathol 19(12): 1638-45 (2006)
2010  
72
Gastro-esophageal reflux disease and irritable bowel syndrome - why are they associated?
[20486743] Rev Esp Enferm Dig 102(4): 225-8 (2010)
2005  
73
Provocation tests in functional gastrointestinal diseases: mechanistic diagnosis and therapeutic intervention.
[15982176] Rev Esp Enferm Dig 97(4): 219-22 (2005)
2011  
74
Gastrointestinal motility disorders in endocrine diseases.
[21532535] Pol Arch Med Wewn 121(4): 129-36 (2011)
2009  
75
The role of serum chromogranin A in diarrhoea predominant irritable bowel syndrome.
[19337629] J Gastrointestin Liver Dis 18(1): 23-6 (2009)
2011  
76
Corticosterone mediates reciprocal changes in CB 1 and TRPV1 receptors in primary sensory neurons in the chronically stressed rat.
[21070780] Gastroenterology 140(2): 627-637.e4 (2011)
2008  
77
Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain.
[18252749] Gut 57(7): 923-9 (2008)
2003  
78
Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency.
[12573376] Lancet 361(9355): 385-91 (2003)
2007  
79
Guidelines on the irritable bowel syndrome: mechanisms and practical management.
[17488783] Gut 56(12): 1770-98 (2007)
2010  
80
Optimizing outcomes with alosetron hydrochloride in severe diarrhea-predominant irritable bowel syndrome.
[21180598] Therap Adv Gastroenterol 3(3): 165-72 (2010)
2009  
81
The treatment of irritable bowel syndrome.
[21180545] Therap Adv Gastroenterol 2(4): 221-38 (2009)
2009  
82
Yield of diagnostic tests for celiac disease in individuals with symptoms suggestive of irritable bowel syndrome: systematic review and meta-analysis.
[19364994] Arch Intern Med 169(7): 651-8 (2009)
2007  
83
Recurrent abdominal pain and irritable bowel syndrome in children.
[17885479] Curr Opin Pediatr 19(5): 581-5 (2007)
2011  
84
Alpha 2 Delta (α(2)δ) Ligands, Gabapentin and Pregabalin: What is the Evidence for Potential Use of These Ligands in Irritable Bowel Syndrome.
[21713059] Front Pharmacol 2(-): 28 (2011)
2010  
85
Lubiprostone: evaluation of the newest medication for the treatment of adult women with constipation-predominant irritable bowel syndrome.
[21151683] Int J Womens Health 2(-): 361-74 (2010)
2011  
86
The role of experimental models in developing new treatments for irritable bowel syndrome.
[21309671] Expert Rev Gastroenterol Hepatol 5(1): 43-57 (2011)
2008  
87
Atopic irritable bowel syndrome: same old hat or a new entity?
[19072394] Expert Rev Gastroenterol Hepatol 2(4): 457-9 (2008)
2010  
88
Irritable bowel syndrome: diagnostic approaches in clinical practice.
[21694856] Clin Exp Gastroenterol 3(-): 127-37 (2010)
2009  
89
Current and novel therapeutic options for irritable bowel syndrome management.
[19665953] Dig Liver Dis 41(12): 854-62 (2009)
2010  
90
Safety and efficacy of tegaserod therapy in patients with irritable bowel syndrome or chronic constipation.
[20410554] Can J Clin Pharmacol 17(1): e194-200 (2010)
2008  
91
Pediatric functional gastrointestinal disorders.
[18595859] Nutr Clin Pract 23(3): 268-74 (2008)
2009  
92
Genetics and irritable bowel syndrome: from genomics to intermediate phenotype and pharmacogenetics.
[19655247] Dig Dis Sci 54(11): 2318-24 (2009)
2009  
93
Widespread hyperalgesia in irritable bowel syndrome is dynamically maintained by tonic visceral impulse input and placebo/nocebo factors: evidence from human psychophysics, animal models, and neuroimaging.
[19375508] Neuroimage 47(3): 995-1001 (2009)
2005  
94
The use of antidepressants in functional gastrointestinal disorders: new uses for old drugs.
[16273017] CNS Spectr 10(11): 891-6 (2005)
2009  
95
Role of anxiety in the pathophysiology of irritable bowel syndrome: importance of the amygdala.
[20582274] Front Neurosci 3(-): 47 (2009)
2008  
96
Novel pharmacology: asimadoline, a kappa-opioid agonist, and visceral sensation.
[18715494] Neurogastroenterol Motil 20(9): 971-9 (2008)
2010  
97
Approaching patients with irritable bowel syndrome.
[20948834] F1000 Med Rep 2(-): - (2010)
2011  
98
Irritable bowel syndrome - An inflammatory disease involving mast cells.
[22053295] Asia Pac Allergy 1(1): 36-42 (2011)
2011  
99
LX-1031, a tryptophan 5-hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotonin.
[21159063] Neurogastroenterol Motil 23(3): 193-200 (2011)
PMC   
100
Is irritable bowel syndrome an organic disorder?
[24574708] World J Gastroenterol 20(2):384-400 (2014)
PMC   
101
Molecular basis of the irritable bowel syndrome.
[24574707] World J Gastroenterol 20(2):376-83 (2014)
PMC   
102
Diagnostic utility of faecal biomarkers in patients with irritable bowel syndrome.
[24574706] World J Gastroenterol 20(2):363-75 (2014)
PMC   
103
Complementary and alternative medicines in irritable bowel syndrome: an integrative view.
[24574705] World J Gastroenterol 20(2):346-62 (2014)
PMC   
104
Irritable bowel syndrome: the evolution of multi-dimensional looking and multidisciplinary treatments.
[24627587] World J Gastroenterol 20(10):2499-514 (2014)
PMC   
105
Melatonin for the treatment of irritable bowel syndrome.
[24627586] World J Gastroenterol 20(10):2492-8 (2014)
PMC   
106
Irritable bowel syndrome and small intestinal bacterial overgrowth: meaningful association or unnecessary hype.
[24627585] World J Gastroenterol 20(10):2482-91 (2014)
PMC   
107
Unraveling the ties between irritable bowel syndrome and intestinal microbiota.
[24627584] World J Gastroenterol 20(10):2470-81 (2014)
PMC   
108
Irritable bowel syndrome: emerging paradigm in pathophysiology.
[24627583] World J Gastroenterol 20(10):2456-69 (2014)
PMC   
109
Overgrowth of the indigenous gut microbiome and irritable bowel syndrome.
[24627582] World J Gastroenterol 20(10):2449-55 (2014)
PMC   
110
Sex hormones in the modulation of irritable bowel syndrome.
[24627581] World J Gastroenterol 20(10):2433-48 (2014)
PMC   
111
Linaclotide: A Novel Therapy for Chronic Constipation and Constipation-Predominant Irritable Bowel Syndrome.
[24683372] Gastroenterol Hepatol (N Y) 8(10):653-60 (2012)
PMC   
112
Long-term efficacy and safety of otilonium bromide in the management of irritable bowel syndrome: a literature review.
[24741324] Clin Exp Gastroenterol 7():75-82 (2014)
PMC   
113
New treatment option for irritable bowel syndrome with constipation and chronic idiopathic constipation.
[24693271] Gastroenterol Hepatol (N Y) 8(12):825-8 (2012)
PMC   
114
Role of gut pathogens in development of irritable bowel syndrome.
[24604037] Indian J Med Res 139(1):11-8 (2014)
PMC   
115
Alterations in composition and diversity of the intestinal microbiota in patients with diarrhea-predominant irritable bowel syndrome.
[22339879] Neurogastroenterol Motil 24(6):521-30, e248 (2012)
PMC   
116
Post-infectious irritable bowel syndrome: mechanistic insights into chronic disturbances following enteric infection.
[24744587] World J Gastroenterol 20(14):3976-85 (2014)

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