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10.1134/S1070428020110020

http://scihub22266oqcxt.onion/10.1134/S1070428020110020
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C7797888/?report=reader!7797888!C7797888
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suck abstract from ncbi


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pmidC7797888      ä-/-ä 2020 ; 56 (11): 1893-904
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  • Synthesis and Properties of 1,3-Disubstituted Ureas and Their Isosteric Analogs Containing Polycyclic Fragments: V 1-(Bicyclo 2 2 1 heptan-2-yl)-3-R- and 1-(1,7,7-Tricyclo 2 2 1 heptan-2-yl)-3-R-ureas #MMPMIDC7797888
  • Pitushkin DA; Burmistrov VV; Saeef MHA; Vernigora AA; Butov GM
  • ä-/-ä 2020[]; 56 (11): 1893-904 PMIDC7797888show ga
  • A series of 1,3-disubstituted ureas containing a bicyclic lipophilic group of natural origin were synthesized by the reactions of bicyclo[2.2.1]heptane-2-yl isocyanate with amines in yields of up to 82% and by the reactions of bicyclo[2.2.1]heptan-2-amine and 1,7,7-trimethylbicyclo[2.2.1]heptan-2-amine with 1,1'-carbonyldiimidazole in yields of up to 94%. The synthesized ureas are potent inhibitors of RNA virus replication and soluble epoxide hydrolase.
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