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Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 ä-/-ä 2021 ; 46 (1): ä Nephropedia Template TP
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The evident and the hidden factors of vitamin D status in older people during COVID-19 pandemic #MMPMIDC7790349
Schmidt Azevedo P; Fock RA; Pereira FL; dos Santos PP; Ferro FC; Sacco N; Polegato BF; Zornoff LM; Okoshi MP; Achterberg W; de Paiva SR
ä-/-ä 2021[]; 46 (1): ä PMIDC7790349show ga
Purpose: Considering the COVID-19 pandemic, vitamin D is a target of research and speculation. Lockdown or home isolation reduces sunlight exposition and increases the risk of vitamin D deficiency. Special attention is needed for older people at risk of both severe forms of COVID-19 and vitamin D deficiency. This review aims to highlight the association of vitamin D and COVID-19 in two instances, the direct influence of vitamin D on the immune system, and the indirect risks for other vitamin D deficiency-related diseases, such as musculoskeletal properties in older persons. Methods: We performed a narrative review. Results: Whether vitamin D deficiency is associated with COVID-19 poor prognosis, and if vitamin D supplementation may improve the post-infection outcomes is still unclear. In any case, the pandemic generates indirect burden, such as the sequence: home isolation, low sunlight exposition, vitamin D deficiency, and fragility fractures. Conclusion: Therefore, it is time to debate how to optimize vitamin D status in older people, especially during the COVID-19 pandemic.