Atteintes pulmonaires liées à la COVID-19 #MMPMIDC7785274
Garnier M; Quesnel C; Constantin JM
ä-/-ä 2021[Feb]; 2 (1): 14-24 PMIDC7785274show ga
SARS-CoV-2, a newly identified ?-coronavirus, is the pathogen responsible for Covid-19 (CoronaVIrus Disease).Systemic immune over activation due to SARS-CoV-2 infection causes the cytokine storm, with severe epithelial lung damage and pulmonary intravascular coagulopathy.Clinical symptoms are heterogeneous, ranging from mild upper respiratory symptoms to even acute respiratory distress syndrome (ARDS).Non-invasive ventilation and high-flow nasal oxygen therapy effectively treat more than half of severe patients without risk to caregivers.Dexamethasone (6 mg/d for 10 days) is the only currently validated treatment.The increased thrombotic risk justifies preventive or even curative anticoagulation depending on the case.