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10.1134/S0006297921030020 http://scihub22266oqcxt.onion/10.1134/S0006297921030020 C7772802!7772802!33838627     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biochemistry+(Mosc) 2021 ; 86 (3): 248-56 Nephropedia Template TP {{tp|p=33838627|t=2021. Structure and Expression of Large (+)RNA Genomes of Viruses of Higher Eukaryotes |pdf=|usr=}}{{33838627}} gab.com Text Structure and Expression of Large (+)RNA Genomes of Viruses of Higher Eukaryotes JO: Biochemistry (Mosc) http://www.kidney.de/pget.php?&tw=1&pmid=33838627 #FOAvip Viral positive-sense RNA genomes evolve rapidly due to the high mutation rates during replication and RNA recombination, which allowing the viruses to acquire and modify genes for their adaptation. The size of RNA genome is limited by several factors, including low fidelity of RNA polymerases and packaging constraints. However, the 12-kb size limit is exceeded in the two groups of eukaryotic (+)RNA viruses ? animal nidoviruses and plant closteroviruses. These virus groups have several traits in common. Their genomes contain 5?-proximal genes that are expressed via ribosomal frameshifting and encode one or two papain-like protease domains, membrane-binding domain(s), methyltransferase, RNA helicase, and RNA polymerase. In addition, some nidoviruses (i.e., coronaviruses) contain replication-associated domains, such as proofreading exonuclease, putative primase, nucleotidyltransferase, and endonuclease. In both nidoviruses and closteroviruses, the 3?-terminal part of the genome contains genes for structural and accessory proteins expressed via a nested set of coterminal subgenomic RNAs. Coronaviruses and closteroviruses have evolved to form flexuous helically symmetrical nucleocapsids as a mean to resolve packaging constraints. Since phylogenetic reconstructions of the RNA polymerase domains indicate only a marginal relationship between the nidoviruses and closteroviruses, their similar properties likely have evolved convergently, along with the increase in the genome size. Twit Text FOAVip Structure and Expression of Large (+)RNA Genomes of Viruses of Higher Eukaryotes ????Biochemistry (Mosc) http://www.kidney.de/pget.php?&tw=1&pmid=33838627 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33838627 #FOAvip English Wikipedia <ref>{{Cite pmid|33838627}}</ref> Structure and Expression of Large (+)RNA Genomes of Viruses of Higher Eukaryotes #MMPMID33838627 Agranovsky AA Biochemistry (Mosc) 2021[]; 86 (3): 248-56 PMID33838627show ga Viral positive-sense RNA genomes evolve rapidly due to the high mutation rates during replication and RNA recombination, which allowing the viruses to acquire and modify genes for their adaptation. The size of RNA genome is limited by several factors, including low fidelity of RNA polymerases and packaging constraints. However, the 12-kb size limit is exceeded in the two groups of eukaryotic (+)RNA viruses ? animal nidoviruses and plant closteroviruses. These virus groups have several traits in common. Their genomes contain 5?-proximal genes that are expressed via ribosomal frameshifting and encode one or two papain-like protease domains, membrane-binding domain(s), methyltransferase, RNA helicase, and RNA polymerase. In addition, some nidoviruses (i.e., coronaviruses) contain replication-associated domains, such as proofreading exonuclease, putative primase, nucleotidyltransferase, and endonuclease. In both nidoviruses and closteroviruses, the 3?-terminal part of the genome contains genes for structural and accessory proteins expressed via a nested set of coterminal subgenomic RNAs. Coronaviruses and closteroviruses have evolved to form flexuous helically symmetrical nucleocapsids as a mean to resolve packaging constraints. Since phylogenetic reconstructions of the RNA polymerase domains indicate only a marginal relationship between the nidoviruses and closteroviruses, their similar properties likely have evolved convergently, along with the increase in the genome size. äStructure and Expression of Large (+)RNA Genomes of Viruses of Higher (epmc).pdf DeepDyve Pubget Overpricing