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10.2217/fvl-2020-0243

http://scihub22266oqcxt.onion/10.2217/fvl-2020-0243
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suck abstract from ncbi


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pmidC7720652      Future+Virol ä ; ä (ä): ä
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  • Phylogenomics and phylodynamics of SARS-CoV-2 genomes retrieved from India #MMPMIDC7720652
  • Farah S; Atkulwar A; Praharaj MR; Khan R; Gandham R; Baig M
  • Future Virol ä[]; ä (ä): ä PMIDC7720652show ga
  • Background: This is the first phylodynamic study attempted on SARS-CoV-2 genomes from India to infer the current state of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolution using phylogenetic network and growth trends. Materials & Methods: Out of 286 retrieved whole genomes from India, 138 haplotypes were used to build a phylogenetic network. The birth?death serial model (BDSIR) package of BEAST2 was used to calculate the reproduction number of SARS-CoV-2. Population dynamics were investigated using the stamp date method as implemented in BEAST2 and BEAST 1.10.4. Results: A median-joining network revealed two ancestral clusters. A high basic reproduction number of SARS-CoV-2 was found. An exponential rise in the effective population size of Indian isolates was detected. Conclusion: The phylogenetic network reveals dual ancestry and possibility of community transmission of SARS-CoV-2 in India.
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