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10.1016/j.apmt.2020.100887 http://scihub22266oqcxt.onion/10.1016/j.apmt.2020.100887 C7718584!7718584 !38620577     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=38620577 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Appl+Mater+Today 2021 ; 22 (?): 100887 Nephropedia Template TP {{tp|p=38620577 |t=2021. Nitric oxide and viral infection: Recent developments in antiviral therapies and platforms |pdf=|usr=}}{{38620577 }} gab.com Text Nitric oxide and viral infection: Recent developments in antiviral therapies and platforms JO: Appl Mater Today http://www.kidney.de/pget.php?&tw=1&pmid=38620577 #FOAvip Nitric oxide (NO) is a gasotransmitter of great significance to developing the innate immune response to many bacterial and viral infections, while also modulating vascular physiology. The generation of NO from the upregulation of endogenous nitric oxide synthases serves as an efficacious method for inhibiting viral replication in host defense and warrants investigation for the development of antiviral therapeutics. With increased incidence of global pandemics concerning several respiratory-based viral infections, it is necessary to develop broad therapeutic platforms for inhibiting viral replication and enabling more efficient host clearance, as well as to fabricate new materials for deterring viral transmission from medical devices. Recent developments in creating stabilized NO donor compounds and their incorporation into macromolecular scaffolds and polymeric substrates has created a new paradigm for developing NO-based therapeutics for long-term NO release in applications for bactericidal and blood-contacting surfaces. Despite this abundance of research, there has been little consideration of NO-releasing scaffolds and substrates for reducing passive transmission of viral infections or for treating several respiratory viral infections. The aim of this review is to highlight the recent advances in developing gaseous NO, NO prodrugs, and NO donor compounds for antiviral therapies; discuss the limitations of NO as an antiviral agent; and outline future prospects for guiding materials design of a next generation of NO-releasing antiviral platforms. Twit Text FOAVip Nitric oxide and viral infection: Recent developments in antiviral therapies and platforms ????Appl Mater Today http://www.kidney.de/pget.php?&tw=1&pmid=38620577 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=38620577 #FOAvip English Wikipedia <ref>{{Cite pmid|38620577 }}</ref> Nitric oxide and viral infection: Recent developments in antiviral therapies and platforms #MMPMID38620577 Garren MR ; Ashcraft M ; Qian Y ; Douglass M ; Brisbois EJ ; Handa H Appl Mater Today 2021[Mar]; 22 (?): 100887 PMID38620577 show ga Nitric oxide (NO) is a gasotransmitter of great significance to developing the innate immune response to many bacterial and viral infections, while also modulating vascular physiology. The generation of NO from the upregulation of endogenous nitric oxide synthases serves as an efficacious method for inhibiting viral replication in host defense and warrants investigation for the development of antiviral therapeutics. With increased incidence of global pandemics concerning several respiratory-based viral infections, it is necessary to develop broad therapeutic platforms for inhibiting viral replication and enabling more efficient host clearance, as well as to fabricate new materials for deterring viral transmission from medical devices. Recent developments in creating stabilized NO donor compounds and their incorporation into macromolecular scaffolds and polymeric substrates has created a new paradigm for developing NO-based therapeutics for long-term NO release in applications for bactericidal and blood-contacting surfaces. Despite this abundance of research, there has been little consideration of NO-releasing scaffolds and substrates for reducing passive transmission of viral infections or for treating several respiratory viral infections. The aim of this review is to highlight the recent advances in developing gaseous NO, NO prodrugs, and NO donor compounds for antiviral therapies; discuss the limitations of NO as an antiviral agent; and outline future prospects for guiding materials design of a next generation of NO-releasing antiviral platforms. ?Nitric oxide and viral infection: Recent developments in antiviral the(epmc).pdf DeepDyve Pubget Overpricing