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10.1080/20002297.2020.1853451

http://scihub22266oqcxt.onion/10.1080/20002297.2020.1853451
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C7711743!7711743!33312449
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suck abstract from ncbi


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pmid33312449      J+Oral+Microbiol ä ; 13 (1): ä
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  • Potential implications of SARS-CoV-2 oral infection in the host microbiota #MMPMID33312449
  • Xiang Z; Koo H; Chen Q; Zhou X; Liu Y; Simon-Soro A
  • J Oral Microbiol ä[]; 13 (1): ä PMID33312449show ga
  • The oral cavity, as the entry point to the body, may play a critical role in the pathogenesis of SARS-CoV-2 infection that has caused a global outbreak of the coronavirus disease 2019 (COVID-19). Available data indicate that the oral cavity may be an active site of infection and an important reservoir of SARS-CoV-2. Considering that the oral surfaces are colonized by a diverse microbial community, it is likely that viruses have interactions with the host microbiota. Patients infected by SARS-CoV-2 may have alterations in the oral and gut microbiota, while oral species have been found in the lung of COVID-19 patients. Furthermore, interactions between the oral, lung, and gut microbiomes appear to occur dynamically whereby a dysbiotic oral microbial community could influence respiratory and gastrointestinal diseases. However, it is unclear whether SARS-CoV-2 infection can alter the local homeostasis of the resident microbiota, actively cause dysbiosis, or influence cross-body sites interactions. Here, we provide a conceptual framework on the potential impact of SARS-CoV-2 oral infection on the local and distant microbiomes across the respiratory and gastrointestinal tracts (?oral-tract axes?), which remains largely unexplored. Studies in this area could further elucidate the pathogenic mechanism of SARS-CoV-2 and the course of infection as well as the clinical symptoms of COVID-19 across different sites in the human host.
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