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Malnutrition Prolongs the Hospitalization of Patients with COVID-19 Infection: A
Clinical Epidemiological Analysis
#MMPMID33575730
Yu Y
; Ye J
; Chen M
; Jiang C
; Lin W
; Lu Y
; Ye H
; Li Y
; Wang Y
; Liao Q
; Zhang D
; Li D
J Nutr Health Aging
2021[]; 25
(3
): 369-373
PMID33575730
show ga
OBJECTIVES: During the 2019 coronavirus disease (COVID-19) outbreak, malnutrition
may contribute to COVID-19 adverse outcomes. We conducted a clinical
epidemiological analysis to investigate the association of malnutrition with
hospitalized duration in patients with COVID-19. DESIGN: Retrospective survey
study. SETTING: Taikang Tongji (Wuhan) hospital in Wuhan, China. PARTICIPANTS:
139 patients with COVID-19. METHODS: In total, 139 patients with COVID-19 from
patients in the Infection Department of Taikang Tongji (Wuhan) hospital from
February 2020 to April 2020 were analyzed retrospectively. We used the "Global
leadership Initiative on Malnutrition(GLIM)" assessment standard published in
2019 to assess nutritional status. Prolonged hospitalization was lasting more
than the median value of the hospitalized days (17 days) in this population.
RESULTS: According to the assessment results of GLIM nutrition assessment, the
patients were divided into malnutrition group and normal nutrition group.
Compared with the patients in the normal nutrition group, the hospitalization
time was longer(15.67±6.26 days versus 27.48±5.04 days, P = 0.001). Kaplan-Meier
analysis showed patients with malnutrition were more likely to be hospitalized
longer compared with those normal nutrition (mean with 95% confidence interval
[CI]: 28.91[27.52-30.30] versus 22.78[21.76-23.79], P = 0.001). COX regression
analysis showed that malnutrition (hazard ratio [HR] = 3.773, P for trend =
0.001) was proportional associated with being discharged from hospital delayed.
CONCLUSION AND IMPLICATIONS: Present findings suggested that malnutrition
contributed to predicting a probability of prolonged hospitalization in patients
with COVID-19 infection, to whom extra attentions and precautions should be paid
during clinical treatments. Based on the existing results, it is recommended that
inpatients with nutritional risk or malnutrition start nutritional support
treatment as soon as possible.
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