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Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 ä-/-ä 2021 ; 9 (ä): 100134 Nephropedia Template TP
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Modeling the effect of contaminated objects for the transmission dynamics of COVID-19 pandemic with self protection behavior changes #MMPMID38620308
Mekonen KG; Habtemicheal TG; Balcha SF
ä-/-ä 2021[Feb]; 9 (ä): 100134 PMID38620308show ga
A mathematical model for the transmission dynamics of Coronavirus diseases (COVID-19) is proposed using a system of nonlinear ordinary differential equations by incorporating self protection behavior changes in the population. The disease free equilibrium point is computed, and both the local and global stability analysis was performed. The basic reproduction number (R0) of the model is computed using the method of next generation matrix. The disease free equilibrium point is locally asymptotically and globally stable under certain conditions. Based on the available data, the unknown model parameters are estimated using a combination of least square and Bayesian estimation methods for different countries. The forward sensitivity index is applied to determine and identify the key model parameters for the spread of disease dynamics. The sensitive parameters for the spread of the virus vary from country to country. We found out that the reproduction number depends mostly on the infection rates, the threshold value of the force of infection for a population, the recovery rates, and the virus decay rate in the environment. It illustrates that control of the effective transmission rate (recommended human behavioral change towards self-protective measures) is essential to stop the spreading of the virus. Numerical simulations of the model were performed to supplement and verify the effectiveness of the analytical findings.