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(1
): 181-91
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Role of gut-lung microbiome crosstalk in COVID-19
#MMPMIDC7685301
Srinath BS
; Shastry RP
; Kumar SB
ä-/-ä 2022[]; 38
(1
): 181-91
PMIDC7685301
show ga
PURPOSE: Gut microbiota are able to generate metabolites that can alter the
function of immune cells and play a major role in health and disease.
Understanding the changes in gut microbiome during infections including virus may
help to use novel strategies in the therapeutic interventions. METHODS: We have
reviewed recent reports on role of gut microbiome in lung infections and its
possible importance in COVID-19. RESULTS: Most of the studies provide an insight
into the possible role of gut microbes during lung diseases including chronic
obstructive pulmonary disease (COPD), cystic fibrosis, lung cancer, and other
respiratory problems such as allergy and asthma. However, clinical evidence
underlying gut-lung crosstalk during respiratory viral infections is limited.
CONCLUSION: This review provides an overview of the role of the gut microbiome
during respiratory viral infections mainly focused on COVID-19 and possible
evidence for its crosstalk targeting as new therapeutics.
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