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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Med+Intensiva+(Engl+Ed)
2021 ; 45
(1
): 14-26
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Comparación de las características demográficas y comorbilidad de los pacientes
con COVID-19 fallecidos en hospitales españoles, en función de si ingresaron o no
en Cuidados Intensivos
#MMPMID33158594
Miró Ò
; Alquézar-Arbé A
; Llorens P
; Martín-Sánchez FJ
; Jiménez S
; Martín A
; Burillo-Putze G
; Jacob J
; García-Lamberechts EJ
; Piñera P
; Del Castillo JG
Med Intensiva (Engl Ed)
2021[Jan]; 45
(1
): 14-26
PMID33158594
show ga
OBJECTIVE: To describe and compare the demographic characteristics and
comorbidities of patients with COVID-19 who died in Spanish hospitals during the
2020 pandemic based on whether they were or were not admitted to an intensive
care unit (ICU) prior to death. METHODS: We performed a secondary analysis of
COVID-19 patients who died during hospitalization included by 62 Spanish
emergency departments in the SIESTA cohort. We collected the demographic
characteristics and comorbidities, determined both individually and estimated
globally by the Charlson index (ChI). Independent factors related to ICU
admission were identified and different analyses of sensitivity were performed to
contrast the consistency of the findings of the principal analysis. RESULTS: We
included the 338 patients from the SIESTA cohort that died during
hospitalization. Of these, 77 (22.8%) were admitted to an ICU before dying. After
multivariate adjustment, 3 out of the 20 basal characteristics analyzed in the
present study were independently associated with ICU admission: dementia (no
patients with dementia who died were admitted to the ICU: OR = 0, 95%CI = not
calculable), active cancer (OR = 0.07; 95%CI = 0.02-0.21) and age (< 70 years: OR
= 1, reference; 70-74 years: OR = 0.21; 95%CI = 0.08-0.54; 75-79 years: OR =
0.21; 95%CI = 0.08-0.54; ? 80 years: OR = 0.02; 95%CI = 0.01-0.05). The
probability of ICU admission significantly increased in parallel to the ChI, even
after adjustment for age (ChI 0 points: OR = 0, reference; ChI 1 point: OR =
0.36; 95%CI = 0.16-0.83; ChI 2 points: OR = 0.36; 95%CI = 0.16-0.83; ChI >2
points: OR = 0.09; 95%CI = 0.04-0.23). The sensitivity analyses showed no gross
differences compared to the principal analysis. CONCLUSIONS: The profile of
COVID-19 patients who died without ICU admission is similar to that observed in
the usual medical practice before the pandemic. The basal characteristics
limiting their admission were age and global burden due to comorbidity,
especially dementia and active cancer.
|*Hospital Mortality
[MESH]
|*SARS-CoV-2
[MESH]
|Age Distribution
[MESH]
|Aged
[MESH]
|Aged, 80 and over
[MESH]
|Analysis of Variance
[MESH]
|Asthma/epidemiology
[MESH]
|COVID-19/epidemiology/*mortality
[MESH]
|Cohort Studies
[MESH]
|Comorbidity
[MESH]
|Confidence Intervals
[MESH]
|Coronary Disease/epidemiology
[MESH]
|Dementia/epidemiology
[MESH]
|Diabetes Mellitus/epidemiology
[MESH]
|Dyslipidemias/epidemiology
[MESH]
|Female
[MESH]
|Humans
[MESH]
|Hypertension/epidemiology
[MESH]
|Intensive Care Units/*statistics & numerical data
[MESH]