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Neopterin Predicts Disease Severity in Hospitalized Patients With COVID-19 #MMPMID33442554
Open Forum Infect Dis 2021[Jan]; 8 (1): ä PMID33442554show ga
This study evaluates the predictive value of circulating inflammatory markers, especially neopterin, in patients with coronavirus disease 2019 (COVID-19). Within this retrospective analysis of 115 hospitalized COVID-19 patients, elevated neopterin levels upon admission were significantly associated with disease severity, risk for intensive care unit admission, need for mechanical ventilation, and death. Therefore, neopterin is a reliable predictive marker in patients with COVID-19 and may help to improve the clinical management of patients.