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Curing piglets from diarrhea and preparation of a healthy microbiome with
Bacillus treatment for industrial animal breeding
#MMPMID33173074
Yue S
; Li Z
; Hu F
; Picimbon JF
Sci Rep
2020[Nov]; 10
(1
): 19476
PMID33173074
show ga
High-throughput farming of animals for an essential purpose such as large scale
health and production of hogs is a challenge for the food industry in the modern
world. The problem is that the breeding of livestock for fast growth or high
yields of meat is often associated with illness and microbial infection that
develop under the breeding conditions. Piglet diarrhea is most common pig
disease, leading to heavy mortality and thereby economic loss. We proved that
chemical drugs can relieve the symptoms of diarrhea in ill piglets, but they do
not treat the underlying cause, i.e. significantly altered bacterial gut flora.
Using Illumina sequencing of fecal DNA, we showed that the bacterial gut flora of
piglets treated with antibiotics remain close to the ill conditions. However,
using Illumina sequencing of fecal DNA from piglets treated with a specific
Bacillus (Bacillus subtilis Y-15, B. amyloliquefaciens DN6502 and B.
licheniformis SDZD02) demonstrated the efficiency of natural bioproducts not only
on curing diarrhea, but also on beneficial bacteria to re-establish in the piglet
gut. We therefore propose a new natural "medicine" to be explored by the world
farm animal agriculture industry, particularly for sustainable improvement of
swine livestock production and health.
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