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10.1183/23120541.00541-2020 http://scihub22266oqcxt.onion/10.1183/23120541.00541-2020 C7607967!7607967!33527074     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       ERJ+Open+Res 2021 ; 7 (1): ä Nephropedia Template TP {{tp|p=33527074|t=2021. Outcomes of COVID-19 patients treated with continuous positive airway pressure outside the intensive care unit |pdf=|usr=}}{{33527074}} gab.com Text Outcomes of COVID-19 patients treated with continuous positive airway pressure outside the intensive care unit JO: ERJ Open Res http://www.kidney.de/pget.php?&tw=1&pmid=33527074 #FOAvip Aim: We aimed to characterise a large population of coronavirus disease 2019 (COVID-19) patients with moderate-to-severe hypoxaemic acute respiratory failure (ARF) receiving continuous positive airway pressure (CPAP) outside the intensive care unit (ICU), and to ascertain whether the duration of CPAP application increased the risk of mortality for patients requiring intubation. Methods: In this retrospective, multicentre cohort study, we included adult COVID-19 patients, treated with CPAP outside ICU for hypoxaemic ARF from 1 March to 15 April, 2020. We collected demographic and clinical data, including CPAP therapeutic goal, hospital length of stay and 60-day in-hospital mortality. Results: The study included 537 patients with a median (interquartile range (IQR) age of 69 (60?76) years. 391 (73%) were male. According to the pre-defined CPAP therapeutic goal, 397 (74%) patients were included in the full treatment subgroup, and 140 (26%) in the do not intubate (DNI) subgroup. Median (IQR) CPAP duration was 4 (1?8) days, while hospital length of stay was 16 (9?27) days. 60-day in-hospital mortality was 34% (95% CI 0.304?0.384%) overall, and 21% (95% CI 0.169?0.249%) and 73% (95% CI 0.648?0.787%) for full treatment and DNI subgroups, respectively. In the full treatment subgroup, in-hospital mortality was 42% (95% CI 0.345?0.488%) for 180 (45%) CPAP failures requiring intubation, and 2% (95% CI 0.008?0.035%) for the remaining 217 (55%) patients who succeeded. Delaying intubation was associated with increased mortality (hazard ratio 1.093, 95% CI 1.010?1.184). Conclusions: We described a large population of COVID-19 patients treated with CPAP outside ICU. Intubation delay represents a risk factor for mortality. Further investigation is needed for early identification of CPAP failures. Twit Text FOAVip Outcomes of COVID-19 patients treated with continuous positive airway pressure outside the intensive care unit ????ERJ Open Res http://www.kidney.de/pget.php?&tw=1&pmid=33527074 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33527074 #FOAvip English Wikipedia <ref>{{Cite pmid|33527074}}</ref> Outcomes of COVID-19 patients treated with continuous positive airway pressure outside the intensive care unit #MMPMID33527074 Vaschetto R; Barone-Adesi F; Racca F; Pissaia C; Maestrone C; Colombo D; Olivieri C; De Vita N; Santangelo E; Scotti L; Castello L; Cena T; Taverna M; Grillenzoni L; Moschella MA; Airoldi G; Borrč S; Mojoli F; Della Corte F; Baggiani M; Baino S; Balbo P; Bazzano S; Bonato V; Carbonati S; Crimaldi F; Daffara V; De Col L; Maestrone M; Malerba M; Moroni F; Perucca R; Pirisi M; Rondi V; Rosalba D; Vanni L; Vigone F; Navalesi P; Cammarota G ERJ Open Res 2021[Jan]; 7 (1): ä PMID33527074show ga Aim: We aimed to characterise a large population of coronavirus disease 2019 (COVID-19) patients with moderate-to-severe hypoxaemic acute respiratory failure (ARF) receiving continuous positive airway pressure (CPAP) outside the intensive care unit (ICU), and to ascertain whether the duration of CPAP application increased the risk of mortality for patients requiring intubation. Methods: In this retrospective, multicentre cohort study, we included adult COVID-19 patients, treated with CPAP outside ICU for hypoxaemic ARF from 1 March to 15 April, 2020. We collected demographic and clinical data, including CPAP therapeutic goal, hospital length of stay and 60-day in-hospital mortality. Results: The study included 537 patients with a median (interquartile range (IQR) age of 69 (60?76) years. 391 (73%) were male. According to the pre-defined CPAP therapeutic goal, 397 (74%) patients were included in the full treatment subgroup, and 140 (26%) in the do not intubate (DNI) subgroup. Median (IQR) CPAP duration was 4 (1?8) days, while hospital length of stay was 16 (9?27) days. 60-day in-hospital mortality was 34% (95% CI 0.304?0.384%) overall, and 21% (95% CI 0.169?0.249%) and 73% (95% CI 0.648?0.787%) for full treatment and DNI subgroups, respectively. In the full treatment subgroup, in-hospital mortality was 42% (95% CI 0.345?0.488%) for 180 (45%) CPAP failures requiring intubation, and 2% (95% CI 0.008?0.035%) for the remaining 217 (55%) patients who succeeded. Delaying intubation was associated with increased mortality (hazard ratio 1.093, 95% CI 1.010?1.184). Conclusions: We described a large population of COVID-19 patients treated with CPAP outside ICU. Intubation delay represents a risk factor for mortality. Further investigation is needed for early identification of CPAP failures. äOutcomes of COVID-19 patients treated with continuous positive airway (epmc).pdf DeepDyve Pubget Overpricing