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10.1016/j.jemermed.2020.10.048 http://scihub22266oqcxt.onion/10.1016/j.jemermed.2020.10.048 C7598546!7598546!33353811     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Emerg+Med 2021 ; 60 (3): 359-64 Nephropedia Template TP {{tp|p=33353811|t=2021. Utility of Hypertonic Saline and Diazepam in COVID-19?Related Hydroxychloroquine Toxicity |pdf=|usr=}}{{33353811}} gab.com Text Utility of Hypertonic Saline and Diazepam in COVID-19 Related Hydroxychloroquine Toxicity JO: J Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=33353811 #FOAvip Background: Hydroxychloroquine (HCQ) poisoning is a life-threatening but treatable toxic ingestion. The scale of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19) and the controversial suggestion that HCQ is a treatment option have led to a significant increase in HCQ use. HCQ poisoning should be at the top-of-mind for emergency providers in cases of toxic ingestion. Treatment for HCQ poisoning includes sodium bicarbonate, epinephrine, and aggressive electrolyte repletion. We highlight the use of hypertonic saline and diazepam. Case Report: We describe the case of a 37-year-old man who presented to the emergency department after the ingestion of approximately 16 g of HCQ tablets (initial serum concentration 4270 ng/mL). He was treated with an epinephrine infusion, hypertonic sodium chloride, high-dose diazepam, sodium bicarbonate, and aggressive potassium repletion. Persistent altered mental status necessitated intubation, and he was managed in the medical intensive care unit until his QRS widening and QTc prolongation resolved. After his mental status improved and it was confirmed that his ingestion was not with the intent to self-harm, he was discharged home with outpatient follow-up. Why Should an Emergency Physician Be Aware of This?For patients presenting with HCQ overdose and an unknown initial serum potassium level, high-dose diazepam and hypertonic sodium chloride should be started immediately for the patient with widened QRS. The choice of hypertonic sodium chloride instead of sodium bicarbonate is to avoid exacerbating underlying hypokalemia which may in turn potentiate unstable dysrhythmia. In addition, early intubation should be a priority in vomiting patients because both HCQ toxicity and high-dose diazepam cause profound sedation. Twit Text FOAVip Utility of Hypertonic Saline and Diazepam in COVID-19 Related Hydroxychloroquine Toxicity ????J Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=33353811 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33353811 #FOAvip English Wikipedia <ref>{{Cite pmid|33353811}}</ref> Utility of Hypertonic Saline and Diazepam in COVID-19?Related Hydroxychloroquine Toxicity #MMPMID33353811 Mahan KM; Hayes BD; North CM; Becker JS; Fenves AZ; Hyppolite G; Khosrowjerdi S; Sinden D; Stearns DA J Emerg Med 2021[Mar]; 60 (3): 359-64 PMID33353811show ga Background: Hydroxychloroquine (HCQ) poisoning is a life-threatening but treatable toxic ingestion. The scale of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19) and the controversial suggestion that HCQ is a treatment option have led to a significant increase in HCQ use. HCQ poisoning should be at the top-of-mind for emergency providers in cases of toxic ingestion. Treatment for HCQ poisoning includes sodium bicarbonate, epinephrine, and aggressive electrolyte repletion. We highlight the use of hypertonic saline and diazepam. Case Report: We describe the case of a 37-year-old man who presented to the emergency department after the ingestion of approximately 16 g of HCQ tablets (initial serum concentration 4270 ng/mL). He was treated with an epinephrine infusion, hypertonic sodium chloride, high-dose diazepam, sodium bicarbonate, and aggressive potassium repletion. Persistent altered mental status necessitated intubation, and he was managed in the medical intensive care unit until his QRS widening and QTc prolongation resolved. After his mental status improved and it was confirmed that his ingestion was not with the intent to self-harm, he was discharged home with outpatient follow-up. Why Should an Emergency Physician Be Aware of This?For patients presenting with HCQ overdose and an unknown initial serum potassium level, high-dose diazepam and hypertonic sodium chloride should be started immediately for the patient with widened QRS. The choice of hypertonic sodium chloride instead of sodium bicarbonate is to avoid exacerbating underlying hypokalemia which may in turn potentiate unstable dysrhythmia. In addition, early intubation should be a priority in vomiting patients because both HCQ toxicity and high-dose diazepam cause profound sedation. äUtility of Hypertonic Saline and Diazepam in COVID-19?Related Hydroxyc(epmc).pdf DeepDyve Pubget Overpricing