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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Rev+Esp+Patol 2021 ; 54 (4): 275-80 Nephropedia Template TP
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Multi-organ pathological findings associated with COVID-19 in postmortem needle core biopsies in four patients and a review of the current literature #MMPMID34544557
González Pessolani T; Muñóz Fernández de Legaria M; Elices Apellániz M; Salinas Moreno S; Lorido Cortés Mdel M; García Sánchez S
Rev Esp Patol 2021[Oct]; 54 (4): 275-80 PMID34544557show ga
Coronavirus disease 2019 (COVID-19) has spread worldwide, resulting in significant morbidity and mortality. Histopathological findings are essential in understanding its pathogenesis and we present our findings from postmortem core needle biopsies in an attempt to share information that may shed some light on this severe pandemic.Different organ samples from four patients with PCR-confirmed COVID-19 at the Infanta Sofía Hospital (Madrid) were studied during the months of April and May, 2020 by six pathologists using routine stains, histochemistry and immunohistochemistry. Results were compared with other reported cases.All patients had a clinical diagnosis of pneumonia and biopsies revealed lung damage in the majority. Heart, liver, spleen and kidney were also studied and abnormalities were found in all cases and are extensively described.The histopathology of organs affected by COVID-19 is vital to the understanding of this disease and its sequelae.