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Vitamin C as prophylaxis and adjunctive medical treatment for COVID-19?
#MMPMID32911430
Feyaerts AF
; Luyten W
Nutrition
2020[Nov]; 79-80
(?): 110948
PMID32911430
show ga
Severe acute respiratory syndrome coronavirus 2 causes the potentially fatal
coronavirus disease 2019 (COVID-19). Already during the outbreak of the severe
acute respiratory syndrome coronavirus 1, the use of vitamin C was suggested.
Many patients with severe COVID-19 have elevated levels of the mediators
interleukin-6 and endothelin-1. These mediators may explain the age dependence of
COVID-19 pneumonia, the preponderance of male and obese or hypertensive patients,
as well as of persons of color and smokers. There is clear evidence that vitamin
C in high doses can reduce these mediators. Vitamin C is cheap and safe. Hence,
using a relatively low dose of vitamin C as prophylaxis, and in cases of severe
COVID-19, an (intravenous) high-dose regimen may be beneficial. Ongoing clinical
trials are expected to provide more definitive evidence.
|*COVID-19 Drug Treatment
[MESH]
|Animals
[MESH]
|Ascorbic Acid/pharmacology/*therapeutic use
[MESH]