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10.1016/j.jhin.2020.07.013 http://scihub22266oqcxt.onion/10.1016/j.jhin.2020.07.013 C7372282!7372282 !32702463     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32702463 &cmd=llinks): Failed to open stream: HTTP request failed! 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Nosocomial COVID-19 infection: examining the risk of mortality The COPE-Nosocomial Study (COVID in Older PEople) |pdf=|usr=}}{{32702463 }} gab.com Text Nosocomial COVID-19 infection: examining the risk of mortality The COPE-Nosocomial Study (COVID in Older PEople) JO: J Hosp Infect http://www.kidney.de/pget.php?&tw=1&pmid=32702463 #FOAvip BACKGROUND: Hospital admissions for non-coronavirus disease 2019 (COVID-19) pathology have decreased significantly. It is believed that this may be due to public anxiety about acquiring COVID-19 infection in hospital and the subsequent risk of mortality. AIM: To identify patients who acquire COVID-19 in hospital (nosocomial COVID-19 infection (NC)) and their risk of mortality compared to those with community-acquired COVID-19 (CAC) infection. METHODS: The COPE-Nosocomial Study was an observational cohort study. The primary outcome was the time to all-cause mortality (estimated with an adjusted hazard ratio (aHR)), and secondary outcomes were day 7 mortality and the time-to-discharge. A mixed-effects multivariable Cox's proportional hazards model was used, adjusted for demographics and comorbidities. FINDINGS: The study included 1564 patients from 10 hospital sites throughout the UK, and one in Italy, and collected outcomes on patients admitted up to April 28(th), 2020. In all, 12.5% of COVID-19 infections were acquired in hospital; 425 (27.2%) patients with COVID died. The median survival time in NC patients was 14 days compared with 10 days in CAC patients. In the primary analysis, NC infection was associated with lower mortality rate (aHR: 0.71; 95% confidence interval (CI): 0.51-0.98). Secondary outcomes found no difference in day 7 mortality (adjusted odds ratio: 0.79; 95% CI: 0.47-1.31), but NC patients required longer time in hospital during convalescence (aHR: 0.49, 95% CI: 0.37-0.66). CONCLUSION: The minority of COVID-19 cases were the result of NC transmission. No COVID-19 infection comes without risk, but patients with NC had a lower risk of mortality compared to CAC infection; however, caution should be taken when interpreting this finding. Twit Text FOAVip Nosocomial COVID-19 infection: examining the risk of mortality The COPE-Nosocomial Study (COVID in Older PEople) ????J Hosp Infect http://www.kidney.de/pget.php?&tw=1&pmid=32702463 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32702463 #FOAvip English Wikipedia <ref>{{Cite pmid|32702463 }}</ref> Nosocomial COVID-19 infection: examining the risk of mortality The COPE-Nosocomial Study (COVID in Older PEople) #MMPMID32702463 Carter B ; Collins JT ; Barlow-Pay F ; Rickard F ; Bruce E ; Verduri A ; Quinn TJ ; Mitchell E ; Price A ; Vilches-Moraga A ; Stechman MJ ; Short R ; Einarsson A ; Braude P ; Moug S ; Myint PK ; Hewitt J ; Pearce L ; McCarthy K J Hosp Infect 2020[Oct]; 106 (2 ): 376-384 PMID32702463 show ga BACKGROUND: Hospital admissions for non-coronavirus disease 2019 (COVID-19) pathology have decreased significantly. It is believed that this may be due to public anxiety about acquiring COVID-19 infection in hospital and the subsequent risk of mortality. AIM: To identify patients who acquire COVID-19 in hospital (nosocomial COVID-19 infection (NC)) and their risk of mortality compared to those with community-acquired COVID-19 (CAC) infection. METHODS: The COPE-Nosocomial Study was an observational cohort study. The primary outcome was the time to all-cause mortality (estimated with an adjusted hazard ratio (aHR)), and secondary outcomes were day 7 mortality and the time-to-discharge. A mixed-effects multivariable Cox's proportional hazards model was used, adjusted for demographics and comorbidities. FINDINGS: The study included 1564 patients from 10 hospital sites throughout the UK, and one in Italy, and collected outcomes on patients admitted up to April 28(th), 2020. In all, 12.5% of COVID-19 infections were acquired in hospital; 425 (27.2%) patients with COVID died. The median survival time in NC patients was 14 days compared with 10 days in CAC patients. In the primary analysis, NC infection was associated with lower mortality rate (aHR: 0.71; 95% confidence interval (CI): 0.51-0.98). Secondary outcomes found no difference in day 7 mortality (adjusted odds ratio: 0.79; 95% CI: 0.47-1.31), but NC patients required longer time in hospital during convalescence (aHR: 0.49, 95% CI: 0.37-0.66). CONCLUSION: The minority of COVID-19 cases were the result of NC transmission. No COVID-19 infection comes without risk, but patients with NC had a lower risk of mortality compared to CAC infection; however, caution should be taken when interpreting this finding. |*Hospital Mortality [MESH] |Adult [MESH] |Age Factors [MESH] |Aged [MESH] |Aged, 80 and over [MESH] |Betacoronavirus [MESH] |COVID-19 [MESH] |Cohort Studies [MESH] |Coronavirus Infections/epidemiology/*mortality/*transmission [MESH] |Cross Infection/epidemiology/*mortality/*transmission [MESH] |Female [MESH] |Frail Elderly/*statistics & numerical data [MESH] |Hospitalization/statistics & numerical data [MESH] |Humans [MESH] |Italy/epidemiology [MESH] |Male [MESH] |Middle Aged [MESH] |Pandemics/statistics & numerical data [MESH] |Pneumonia, Viral/epidemiology/*mortality/*transmission [MESH] |Proportional Hazards Models [MESH] |Risk Assessment/*statistics & numerical data [MESH] |Risk Factors [MESH] |SARS-CoV-2 [MESH]Nosocomial COVID-19 infection: examining the risk of mortality The (epmc).pdf DeepDyve Pubget Overpricing