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2020 ; 166
(ä): 108331
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Demographic and clinical features of critically ill patients with COVID-19 in
Greece: The burden of diabetes and obesity
#MMPMID32682810
Halvatsiotis P
; Kotanidou A
; Tzannis K
; Jahaj E
; Magira E
; Theodorakopoulou M
; Konstandopoulou G
; Gkeka E
; Pourzitaki C
; Kapravelos N
; Papoti S
; Sileli M
; Gogos C
; Velissaris D
; Markou N
; Stefanatou E
; Vlachogianni G
; Aimoniotou E
; Komnos A
; Zafeiridis T
; Koulouvaris P
; Armaganidis A
; Bamias A
; Dimopoulos G
Diabetes Res Clin Pract
2020[Aug]; 166
(ä): 108331
PMID32682810
show ga
AIMS: The aim of the study was to investigate the association between type-2
diabetes mellitus, other underlying diseases and obesity with the outcomes of
critically ill Covid-19 patients in Greece. METHODS: In this retrospective
observational multi-centre study, data and outcomes of 90 RNA 2109-nCoV confirmed
critically ill patients from 8 hospitals throughout Greece, were analysed. All
reported information stand through April 13th 2020. RESULTS: The median age of
the patients was 65.5 (IQR 56-73), majority were male (80%) and obesity was
present in 34.4% of patients most prevalent to younger than 55 years.
Hypertension was the prevailing comorbidity (50%), followed by cardiovascular
diseases (21.1%) and type-2 diabetes (18.9%). At admission, common symptoms
duration had a median of 8 (IQR 5-11) days. A 13.3% of the patients were
discharged, 53.4% were still in the ICUs and 28.9% deceased who were hospitalised
for fewer days than the survivors [6 (IQR 3-9) vs. 9 (IQR 7-14.5) respectively].
Aging was not a risk factor but diabetes deteriorates the outcomes. Obesity poses
a suggestive burden as it was more notable in deceased versus survivors.
CONCLUSIONS: Type 2 diabetes and obesity may have contributed to disease severity
and mortality in COVID-19 critically ill patients in Greece.