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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Thromb+Thrombolysis
2020 ; 50
(4
): 795-798
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How haemophilia A impacts severe acute respiratory syndrome coronavirus 2
(SARS-Cov-2) treatment: a case report
#MMPMID32676882
Zanon E
; Pasca S
; Campello E
; Spiezia L
; Vettor R
; Simioni P
J Thromb Thrombolysis
2020[Nov]; 50
(4
): 795-798
PMID32676882
show ga
The typical symptoms of COVID-19 mimic those of the common season flu. In
addition, several changes in the coagulation processes have been observed. To
date, it's not fully clear how COVID-19 may affect patients with hereditary
bleeding disorders. Anticoagulation in patients with haemophilia is still
debated, but in this case could be needed. We are reporting a case of an elderly
patient with mild haemophilia A hospitalized for Sars-Cov-2. On the 15th day of
hospitalization, we observed an increase of all coagulation parameters. An
antithrombotic prophylaxis at low dosage was immediately started, then increased
at prophylactic dosage. Even if much more data are needed to ascertain the real
thrombotic risk of haemophilia A in COVID-19 patients, it's clear that the FVIII
and vWF should be strictly monitored in order to promptly establish an adequate
treatment and avoid the onset of thromboembolic events, even fatal, causing many
deaths in COVID-19 patients.