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2020 ; 13
(10
): 1397-1404
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Molecular pathogenesis of secondary bacterial infection associated to viral
infections including SARS-CoV-2
#MMPMID32712106
Manna S
; Baindara P
; Mandal SM
J Infect Public Health
2020[Oct]; 13
(10
): 1397-1404
PMID32712106
show ga
Secondary bacterial infections are commonly associated with prior or concomitant
respiratory viral infections. Viral infections damage respiratory airways and
simultaneously defects both innate and acquired immune response that provides a
favorable environment for bacterial growth, adherence, and facilitates invasion
into healthy sites of the respiratory tract. Understanding the molecular
mechanism of viral-induced secondary bacterial infections will provide us a
chance to develop novel and effective therapeutic approaches for disease
prevention. The present study describes details about the secondary bacterial
infection during viral infections and their immunological changes.The outcome of
discussion avails an opportunity to understand possible secondary bacterial
infections associated with novel SARS-CoV-2, presently causing pandemic outbreak
COVID-19.