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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 BMJ+Open+Gastroenterol
2020 ; 7
(1
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Correlation between gastrointestinal symptoms and disease severity in patients
with COVID-19: a systematic review and meta-analysis
#MMPMID32665397
Liu J
; Cui M
; Yang T
; Yao P
BMJ Open Gastroenterol
2020[Jul]; 7
(1
): ä PMID32665397
show ga
OBJECTIVE: To study the correlation between gastrointestinal (GI) symptoms and
disease severity in patients with COVID-19. DESIGN: We searched six databases
including three Chinese and three English databases for all the published
articles on COVID-19. Studies were screened according to inclusion and exclusion
criteria. The relevant data were extracted and all the statistical analyses were
performed using Revman5.3. RESULT: In a meta-analysis of 9 studies, comprising
3022 patients, 479 patients (13.7%, 95%?CI 0.125 to 0.149) had severe disease and
624 patients (14.7%, 95%?CI 0.136 to 0.159) had GI symptoms. Of 624 patients with
GI symptoms, 118 patients had severe disease (20.5%, 95%?CI 0.133 to 0.276) and
of 2397 cases without GI symptoms, 361 patients had severe disease (18.2%, 95%?CI
0.129 to 0.235). Comparing disease severity of patients with and without GI
symptoms, the results indicated: I²=62%, OR=1.21, 95%?CI 0.94 to 1.56, p=0.13;
there was no statistically significant difference between the two groups. The
funnel plot was symmetrical with no publication bias. CONCLUSION: Current results
are not sufficient to demonstrate a significant correlation between GI symptoms
and disease severity in patients with COVID-19.
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