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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Thromb+Thrombolysis
2020 ; 50
(3
): 596-603
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Impact of the COVID-19 pandemic on hyperacute stroke treatment: experience from a
comprehensive stroke centre in Singapore
#MMPMID32661758
Paliwal PR
; Tan BYQ
; Leow AST
; Sibi S
; Chor DWP
; Chin AXY
; Yau YW
; Cross GB
; Wong LYH
; Chia MLJ
; Quak Z
; Chua CYK
; Tang DKK
; Zune ET
; Hung J
; Goh Y
; Jing M
; Gopinathan A
; Yang C
; Ahmad A
; Khoo DXL
; Lee CM
; Seet RCS
; Sharma VK
; Teoh HL
; Yeo LLL
; Chan BPL
J Thromb Thrombolysis
2020[Oct]; 50
(3
): 596-603
PMID32661758
show ga
The Coronavirus disease 2019 (COVID-19) pandemic is rapidly evolving and
affecting healthcare systems across the world. Singapore has escalated its alert
level to Disease Outbreak Response System Condition (DORSCON) Orange, signifying
severe disease with community spread. We aimed to study the overall volume of AIS
cases and the delivery of hyperacute stroke services during DORSCON Orange. This
was a single-centre, observational cohort study performed at a comprehensive
stroke centre responsible for AIS cases in the western region of Singapore, as
well as providing care for COVID-19 patients. All AIS patients reviewed as an
acute stroke activation in the Emergency Department (ED) from November 2019 to
April 2020 were included. System processes timings, treatment and clinical
outcome variables were collected. We studied 350 AIS activation patients admitted
through the ED, 206 (58.9%) pre- and 144 during DORSCON Orange. Across the study
period, number of stroke activations showed significant decline (p?=?0.004, 95%
CI 6.513 to?-?2.287), as the number of COVID-19 cases increased exponentially,
whilst proportion of activations receiving acute recanalization therapy remained
stable (p?=?0.519, 95% CI?-?1.605 to 2.702). Amongst AIS patients that received
acute recanalization therapy, early neurological outcomes in terms of change in
median NIHSS at 24 h (-4 versus -4, p?=?0.685) were largely similar between the
pre- and during DORSCON orange periods. The number of stroke activations
decreased while the proportion receiving acute recanalization therapy remained
stable in the current COVID-19 pandemic in Singapore.
|Aged
[MESH]
|COVID-19
[MESH]
|Comprehensive Health Care/*organization & administration
[MESH]