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10.1016/j.rmed.2020.106085

http://scihub22266oqcxt.onion/10.1016/j.rmed.2020.106085
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suck abstract from ncbi


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pmid32917356
      Respir+Med 2020 ; 171 (ä): 106085
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  • Significant reduction in hospital admissions for acute exacerbation of chronic obstructive pulmonary disease in Hong Kong during coronavirus disease 2019 pandemic #MMPMID32917356
  • Chan KPF ; Ma TF ; Kwok WC ; Leung JKC ; Chiang KY ; Ho JCM ; Lam DCL ; Tam TCC ; Ip MSM ; Ho PL
  • Respir Med 2020[Sep]; 171 (ä): 106085 PMID32917356 show ga
  • BACKGROUND: Chronic respiratory diseases are risk factors for severe disease in coronavirus disease 2019 (COVID-19). Respiratory tract infection is one of the commonest causes of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). There has not been evidence suggesting the link between COVID-19 and AECOPD, especially in places with dramatic responses in infection control with universal masking and aggressive social distancing. METHODS: This is a retrospective study to assess the number of admissions of AECOPD in the first three months of 2020 in Queen Mary Hospital with reference to the admissions in past five years. Log-linear model was used for statistical inference of covariates, including percentage of masking, air quality health index and air temperature. RESULTS: The number of admissions for AECOPD significantly decreased by 44.0% (95% CI 36.4%-52.8%, p < 0.001) in the first three months of 2020 compared with the monthly average admission in 2015-2019. Compare to same period of previous years, AECOPD decreased by 1.0% with each percent of increased masking (p < 0.001) and decreased by 3.0% with increase in 1 °C in temperature (p = 0.045). The numbers of admissions for control diagnoses (heart failure, intestinal obstruction and iron deficiency anaemia) in the same period in 2020 were not reduced. CONCLUSIONS: The number of admissions for AECOPD decreased in first three months of 2020, compared with previous years. This was observed with increased masking percentage and social distancing in Hong Kong. We postulated universal masking and social distancing during COVID-19 pandemics both contributed in preventing respiratory tract infections hence AECOPD.
  • |*COVID-19/epidemiology/therapy [MESH]
  • |*Coronavirus Infections/epidemiology/therapy [MESH]
  • |*Pandemics [MESH]
  • |*Pneumonia, Viral/epidemiology/therapy [MESH]
  • |*Pulmonary Disease, Chronic Obstructive/epidemiology/therapy [MESH]
  • |*Respiratory Tract Infections/epidemiology/etiology/prevention & control [MESH]
  • |Air Pollution/analysis [MESH]
  • |Betacoronavirus/isolation & purification [MESH]
  • |Female [MESH]
  • |Hong Kong/epidemiology [MESH]
  • |Humans [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Patient Admission/*statistics & numerical data [MESH]
  • |Respiratory Protective Devices/statistics & numerical data [MESH]
  • |Retrospective Studies [MESH]
  • |Risk Factors [MESH]
  • |SARS-CoV-2 [MESH]


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