
| 10.1016/j.matlet.2020.128320
http://scihub22266oqcxt.onion/10.1016/j.matlet.2020.128320
 C7354272!7354272
!32834257
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Mater+Lett
2020 ; 277
(�): 128320
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gab.com Text
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English Wikipedia
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Modification of cellulose microfibers by polyglutamic acid and mesoporous silica
nanoparticles for Enterovirus 71 adsorption
#MMPMID32834257
Sun M
; Wang H
; Li X
Mater Lett
2020[Oct]; 277
(�): 128320
PMID32834257
show ga
In this study, we synthesized a novel kind of cellulose-based microfibers for
efficient adsorption of Enterovirus 71 (EV71), the leading causative agent of
life-threatening hand, foot and mouth disease. The initial cellulose microfibers
(CEL) were activated by (3-aminopropyl) triethoxysilane (APTES), and then
covalently modified by polyglutamic acid (PGA) and mesoporous silica
nanoparticles (MSN), obtaining the microfibers CEL-PGA-MSN. Owing to the
electrostatic interaction between the negatively charged components (i.e., PGA
and MSN) and positively charged amino acids of the epitope of EV71 capsid protein
VP2 (VP2-ep), the obtained microfibers strongly adsorbed the epitope, and
exhibited high EV71-adsorption capacity. This study sheds a novel light on
development of cellulose-based materials for application in virus-capturing
equipment.
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