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10.1016/j.matlet.2020.128320

http://scihub22266oqcxt.onion/10.1016/j.matlet.2020.128320
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suck abstract from ncbi


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pmid32834257
      Mater+Lett 2020 ; 277 (�): 128320
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  • Modification of cellulose microfibers by polyglutamic acid and mesoporous silica nanoparticles for Enterovirus 71 adsorption #MMPMID32834257
  • Sun M ; Wang H ; Li X
  • Mater Lett 2020[Oct]; 277 (�): 128320 PMID32834257 show ga
  • In this study, we synthesized a novel kind of cellulose-based microfibers for efficient adsorption of Enterovirus 71 (EV71), the leading causative agent of life-threatening hand, foot and mouth disease. The initial cellulose microfibers (CEL) were activated by (3-aminopropyl) triethoxysilane (APTES), and then covalently modified by polyglutamic acid (PGA) and mesoporous silica nanoparticles (MSN), obtaining the microfibers CEL-PGA-MSN. Owing to the electrostatic interaction between the negatively charged components (i.e., PGA and MSN) and positively charged amino acids of the epitope of EV71 capsid protein VP2 (VP2-ep), the obtained microfibers strongly adsorbed the epitope, and exhibited high EV71-adsorption capacity. This study sheds a novel light on development of cellulose-based materials for application in virus-capturing equipment.



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