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Avula A
; Gill A
; Nassar R
; Nalleballe K
; Siddamreddy S
; Chalhoub M
J Clin Neurosci
2020[Sep]; 79
(?): 80-83
PMID33070924
show ga
Coronavirus Disease 2019 (COVID-19) can be associated with various neurological
manifestations including acute strokes. Hyper acute diagnosis and treatment are
key factors which decrease mortality and morbidity in stroke patients. The
COVID-19 pandemic has introduced a great strain on the healthcare system, and as
a result clinicians are facing several barriers in diagnosing and treating
strokes. Delayed presentation of strokes is a problem as some in the general
population defer the decision to seek immediate medical attention fearing
contracting the virus. Also playing a role is the paucity of healthcare
professionals available during a pandemic. Recent literature demonstrates the
association of acute strokes in young patients with COVID-19. Lack of clear
pathophysiology of the neurological manifestations from COVID-19 intensifies the
problem. A thorough examination of the intensive care unit patient has always
been a challenge owing to several factors including use of sedatives, sepsis,
uremia, and encephalopathy secondary to medications. Locked-In Syndrome (LIS)
secondary to stroke is much more challenging to diagnose as patients are unable
to communicate or elicit any motor functions apart from certain ocular movements.
We present the case of a 25 year old patient with no known history of
coagulopathy, but had developed COVID-19 cytokine storm which culminated in LIS
secondary to pontine strokes.
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